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Cumulus cell-mediated sperm selection enhances blastocyst quality using sibling oocytes
Cumulus cell-mediated sperm selection enhances blastocyst quality using sibling oocytes
Can sperm selection through cumulus cells improve embryo quality compared to conventional methods, and is its effectivenes...
Disruption of meiotic double-strand break dynamics provokes germline human infertility in both sexes
Disruption of meiotic double-strand break dynamics provokes germline human infertility in both sexes
To explore genetic basis leading to meiotic disruption in human gametogenesis via exome sequencing. This study in...
Effectiveness of preimplantation genetic testing in sickle cell disease: insights from a single-center experience
Effectiveness of preimplantation genetic testing in sickle cell disease: insights from a single-center experience
Sickle-cell disease (SCD) is a severe autosomal recessive disorder. At-risk couples may prevent transmission either throug...
Efficacy of dual triggering in poor ovarian responders defined according to Bologna and POSEIDON criteria: a systematic review with meta-analysis
Efficacy of dual triggering in poor ovarian responders defined according to Bologna and POSEIDON criteria: a systematic review with meta-analysis
To compare dual triggering versus hCG-only triggering in poor responders undergoing controlled ovarian stimulation with a ...
Cathepsin B expression during in vitro maturation of buffalo COCs: apoptosis and developmental competence
Cathepsin B expression during in vitro maturation of buffalo COCs: apoptosis and developmental competence
The current study aimed to investigate whether cathepsin B (cath B) inhibition in cumulus cells of morphologically graded ...
Factors influencing decisions regarding the fate of frozen embryos in reproductive treatments
Factors influencing decisions regarding the fate of frozen embryos in reproductive treatments
Advances in assisted reproductive technologies (ART) have led to an increasing number of surplus embryos being cryopreserv...
Wharton’s jelly–derived mesenchymal stem cells promote the survival and early development of pre-antral follicles
Wharton’s jelly–derived mesenchymal stem cells promote the survival and early development of pre-antral follicles
To evaluate the effects of indirect co-culture of fresh or vitrified ovarian fragments (OFs) with Wharton’s jelly...
Validation and clinical study of single-step vitrification combined with single-step warming of human blastocysts
Validation and clinical study of single-step vitrification combined with single-step warming of human blastocysts
This study assesses the feasibility of single-step vitrification and warming (SSV/SSW) for human blastocysts. Previous ani...
Metabolic imprinting in trophoblast barrier dysfunction: the role of glucolipotoxicity, endoplasmic reticulum stress, and amino acid transport imbalance
Metabolic imprinting in trophoblast barrier dysfunction: the role of glucolipotoxicity, endoplasmic reticulum stress, and amino acid transport imbalance
The syncytiotrophoblast is central to maternal–fetal exchange and endocrine regulation, with its barrier integrity e...
Dynamic associations between ambient air pollution and transitions of biochemical pregnancy, clinical pregnancy, and live birth among women treated with IVF/ICSI
Dynamic associations between ambient air pollution and transitions of biochemical pregnancy, clinical pregnancy, and live birth among women treated with IVF/ICSI
To examine whether exposure to air pollution around the fresh embryo transfer affects the dynamic progression from inferti...
Sperm plasma membrane potential as a marker for fertilization success for non-normozoospermic patients undergoing assisted reproduction technologies
Sperm plasma membrane potential as a marker for fertilization success for non-normozoospermic patients undergoing assisted reproduction technologies
Semen analysis is a standard tool for assessing male fertility, but it frequently fails to accurately predict fertilizatio...
Influencing factors and clinical significance of mosaic embryos in preimplantation genetic testing
Influencing factors and clinical significance of mosaic embryos in preimplantation genetic testing
To investigate the incidence of mosaic embryos and identify factors influencing their occurrence. In this retrospective co...
A common cause of non-obstructive azoospermia: biallelic variants and implications for infertility diagnostics
A common cause of non-obstructive azoospermia: biallelic variants and implications for infertility diagnostics
Infertility affects about 15% of couples globally, with genetic factors contributing significantly. Advances in genomic te...
A homozygous frameshift variant triggers azoospermia and reveals a strong selective constraint on germline genome integrity
A homozygous frameshift variant triggers azoospermia and reveals a strong selective constraint on germline genome integrity
PIWI proteins and their associated piRNAs constitute a highly conserved pathway that is essential for maintaining germline...
The molecular puzzle of recurrent implantation failure: integrating genetic, epigenetic, and immune mechanisms for precision reproductive medicine
The molecular puzzle of recurrent implantation failure: integrating genetic, epigenetic, and immune mechanisms for precision reproductive medicine
Recurrent implantation failure (RIF) is a frustrating condition for the majority of infertile couples, occurring when preg...
AI-based imputation of anti-Müllerian hormone enables robust prediction of oocyte retrieval during controlled ovarian stimulation
AI-based imputation of anti-Müllerian hormone enables robust prediction of oocyte retrieval during controlled ovarian stimulation
This study addressed the practical challenge of missing data in assisted reproductive technology by evaluating the reliabi...
Successful pre-implantation genetic testing for autosomal recessive cutis laxa: clinical utility of a multidisciplinary team approach
Successful pre-implantation genetic testing for autosomal recessive cutis laxa: clinical utility of a multidisciplinary team approach
Pre-implantation genetic testing for monogenic disorders (PGT-M) enables couples at risk of transmitting serious genetic d...
Autophagy-related biomarkers in non-obstructive azoospermia: insights from transcriptomics and single-cell sequencing
Autophagy-related biomarkers in non-obstructive azoospermia: insights from transcriptomics and single-cell sequencing
Autophagy, by modulating cellular degradation and recycling processes, affects sperm cell survival and differentiation and...
Exposure to nanoscale graphene oxide deteriorates the quality of porcine oocytes via induction of oxidative stress and the apoptosis
Exposure to nanoscale graphene oxide deteriorates the quality of porcine oocytes via induction of oxidative stress and the apoptosis
Nano graphene oxide (nGO), as a type of engineered carbon nanomaterial, has witnessed significant growth in biomedical app...
A novel targeted long-read sequencing-based preimplantation genetic testing method for α-thalassemia (tlrPGT-α-thal)
A novel targeted long-read sequencing-based preimplantation genetic testing method for α-thalassemia (tlrPGT-α-thal)
The purpose is to develop a preimplantation genetic testing (PGT) method for α-thalassemia in one reaction, without r...
Successful assisted reproduction treatment and its psychological outcomes for parents and children: a systematic review and meta-analysis
Successful assisted reproduction treatment and its psychological outcomes for parents and children: a systematic review and meta-analysis
Overcoming infertility through assisted reproductive technology (ART) is stressful and requires a high level of investment...
Virtual reality-based intervention to improve pre-operative anxiety in patients undergoing planned oocyte cryopreservation: a randomized clinical trial
Virtual reality-based intervention to improve pre-operative anxiety in patients undergoing planned oocyte cryopreservation: a randomized clinical trial
To investigate the impact of virtual reality (VR) exposure on anxiety levels in patients undergoing planned oocyte cryopre...
Live birth and other reproductive outcomes of mosaic and euploid embryos: a systematic review and meta-analysis
Live birth and other reproductive outcomes of mosaic and euploid embryos: a systematic review and meta-analysis
Advances in preimplantation genetic testing for aneuploidy (PGT-A) have improved embryo selection in assisted reproductive...
Changes in sequencing technology used for preimplantation genetic testing for aneuploidy
Changes in sequencing technology used for preimplantation genetic testing for aneuploidy
The continued development of assisted reproductive technologies has aimed to improve pregnancy outcomes through screening ...
Time-series clustering of the migration speed of nucleolus-precursor bodies in human zygotes and live birth following assisted reproductive technology
Time-series clustering of the migration speed of nucleolus-precursor bodies in human zygotes and live birth following assisted reproductive technology
Nucleolus-precursor body (NPB) migration speed in human zygotes predicts live birth after assisted reproduction. However, ...
The dynamics of DNA methylation, histone methylation and acetylation during oocyte aging in mammalian species and possible interventions to regulate them
The dynamics of DNA methylation, histone methylation and acetylation during oocyte aging in mammalian species and possible interventions to regulate them
Oocyt e development from non-growing to metaphase II (MII) stages is largely dependent on timely and correctly controlling...
Placental miRNA profiling in assisted reproductive technology (ART) pregnancies
Placental miRNA profiling in assisted reproductive technology (ART) pregnancies
Assisted reproductive technology (ART) procedures are associated with placental dysfunction involving dysregulation of sev...
Evaluating non-invasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A) from spent culture medium: prolonged embryo culture to day 6 increases informativity without negatively impacting quality and live birth rates
Evaluating non-invasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A) from spent culture medium: prolonged embryo culture to day 6 increases informativity without negatively impacting quality and live birth rates
Embryos release cell-free DNA into spent culture medium (SCM), mostly from day 5 to day 6, making extended culture to day ...
Expression of marker genes to assess the spermatogenic capacity in patients with idiopathic non-obstructive azoospermia
Expression of marker genes to assess the spermatogenic capacity in patients with idiopathic non-obstructive azoospermia
To develop a robust quantitative method for assessing testicular spermatogenic capacity in patients with idiopathic non-ob...
Treatment with isotretinoin can improve de novo sperm production in nonobstructive azoospermia or cryptozoospermia
Treatment with isotretinoin can improve de novo sperm production in nonobstructive azoospermia or cryptozoospermia
Retinoic acid (RA), a metabolite of vitamin A, is required for mammalian spermatogenesis. Clinically, intratesticular RA c...
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