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An exploratory study of new predictive biomarkers of castration resistance
Data published in the British Journal of Cancer describe the identification and analysis of four biomarkers that could be ...
Bringing bi-paternal offspring a step closer
Bi-paternal mice that survived to adulthood have been successfully created, according to new research published in Cell St...
Addressing diversity barriers in prostate cancer clinical trials for equitable healthcare outcomes
Prostate cancer is the most common cancer in men, yet disparities persist in screening, diagnosis and treatment among popu...
Treatment strategies in human papillomavirus-related advanced penile cancer
Treatment strategies in human papillomavirus-related advanced penile cancer
Penile cancer is a rare neoplasm with heterogeneous prevalence influenced by risk factors such as smoking, poor hygiene an...
Bladder instillations of gentamicin to treat refractory recurrent urinary tract infection
Bladder instillation of gentamicin is safe and effective in treating recurrent urinary tract infection that has failed to ...
Navigating burnout in healthcare: the price of care in an uncaring system
Burnout in healthcare is not merely a by-product of overwork, but a systemic issue driven by a culture of relentless produ...
Advancing perioperative care in MIBC: insights from NIAGARA
The results of the NIAGARA trial have considerably advanced treatment for patients with muscle-invasive bladder cancer, es...
Assessing the effects of prostate cancer therapies on cardiovascular health
Assessing the effects of prostate cancer therapies on cardiovascular health
Contemporary advances in prostate cancer treatments have markedly improved patient outcomes, yet concerns persist regardin...
Human-relevant urothelial model provides insight into infection strategies and host response
Use of a 3D urine-tolerant human urothelial model (3D-UHU), which recapitulates the crucial features of human urothelium, ...
Management and cost of stent encrustation in pregnancy
Ureteral stents are useful devices for urological management in pregnancy. However, stent encrustation occurs in up to 13%...
Clinical application of bladder MRI and the Vesical Imaging-Reporting And Data System
Diagnostic work-up and risk stratification in patients with bladder cancer before and after treatment must be refined to o...
Genetic and biological drivers of prostate cancer disparities in Black men
Genetic and biological drivers of prostate cancer disparities in Black men
Black men with prostate cancer have historically had worse outcomes than white men with prostate cancer. The causes of thi...
Generative AI in scientific publishing: disruptive or destructive?
Artificial intelligence (AI) has the potential to revolutionize scientific publishing. The influence of AI could be disrup...
Idea sprint: generating research priorities for urinary stone disease
The escalating global prevalence of urinary stone disease and its impact on public health reflects the need to synthesize ...
Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer
Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer
The stromal component of the tumour microenvironment in primary and metastatic prostate cancer can influence and promote d...
Bladder-sparing neoadjuvant therapy for MIBC
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Resolving the puzzle of same-sex sexual interactions
Sexual interactions between members of the same sex are common but the reasons for these behaviours are not always clear. ...
Hallmark discoveries in the biology of Wilms tumour
Hallmark discoveries in the biology of Wilms tumour
The modern study of Wilms tumour was prompted nearly 50 years ago, when Alfred Knudson proposed the ‘two-hit’ ...
Frequency, morbidity and equity — the case for increased research on male fertility
Frequency, morbidity and equity — the case for increased research on male fertility
Currently, most men with infertility cannot be given an aetiology, which reflects a lack of knowledge around gamete produc...
Family dynamics: fathers’ smoking affects children’s epigenetics
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Kidney xenotransplantation
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Unlocking the mystery of the human Y chromosome
Much of the Y chromosome has remained obscure owing to the challenge of sequencing repetitive genomic regions. Recently, t...
Diagnostic liquid biopsy biomarkers in renal cell cancer
Diagnostic liquid biopsy biomarkers in renal cell cancer
The clinical presentation of renal cell cancer (RCC) is shifting towards incidental and early detection, creating new chal...
Improved phenotypic classification of male infertility to promote discovery of genetic causes
Improved phenotypic classification of male infertility to promote discovery of genetic causes
An increasing number of genes are being described in the context of non-syndromic male infertility. Linking the underlying...
Feasibility and potential of an MRI-based prostate cancer screening
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Accessing information in the AI age
Online sources are increasingly being used by patients to obtain medical information. The newest of these resources, artif...
Proteomic-based analysis of testicular interstitial fluid
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A fully transperineal approach for prostate biospy
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A clinical guide to rare male sexual disorders
A clinical guide to rare male sexual disorders
Conditions referred to as ‘male sexual dysfunctions’ usually include erectile dysfunction, ejaculatory disorde...
PSMA-targeted fluorescence guidance for robotic-assisted prostatectomy
PSMA-targeted fluorescence guidance for robotic-assisted prostatectomy
Positive surgical margins are an independent risk factor for biochemical recurrence after radical prostatectomy. However, ...