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Functional variants in the chromosome 4q21 locus contribute to allergic rhinitis risk by modulating the expression of N‐acylethanolamine acid amidase
Functional variants in the chromosome 4q21 locus contribute to allergic rhinitis risk by modulating the expression of N‐acylethanolamine acid amidase
Abstract Background Previous haplotype-based association studies identified chromosome 4q21 as an allergic rhinitis (AR) s...
Milk allergy over‐diagnosis
Milk allergy over‐diagnosis
A basic principle of allergy diagnosis is that reactions depend on exposure to the relevant antigen, and the pattern of re...
Hypotheses to explain the associations between asthma and the consequences of COVID‐19 infection
Hypotheses to explain the associations between asthma and the consequences of COVID‐19 infection
1 HYPOTHESES An allergic T-helper lymphocyte type-2 (Th-2) pattern of immune response plays a role in p...
In response to Frequency of guideline‐defined cow's milk allergy symptoms in infants: Secondary analysis of EAT trial data by Vincent et al
In response to Frequency of guideline‐defined cow's milk allergy symptoms in infants: Secondary analysis of EAT trial data by Vincent et al
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Microbiota Associations with Inflammatory Pathways in Asthma
Microbiota Associations with Inflammatory Pathways in Asthma
Abstract Background The airway microbiota plays an important role in asthma pathophysiology. However, the relationship bet...
Cat allergen exposure in a naturalistic exposure chamber: a prospective observational study in cat‐allergic subjects
Cat allergen exposure in a naturalistic exposure chamber: a prospective observational study in cat‐allergic subjects
Abstract Background To determine the proportion and reproducibility of cat-allergic mild asthmatics with early asthmatic r...
Suppression function against environmental dust exposure after Dermatophagoides pteronyssinus immunotherapy is associated with production of specific and cross‐reactive immunoglobulin G4
Suppression function against environmental dust exposure after Dermatophagoides pteronyssinus immunotherapy is associated with production of specific and cross‐reactive immunoglobulin G4
Abstract Background Whether Dermatophagoides pteronyssinus (Der-p) allergen immunotherapy (AIT) can induce Dermatophagoide...
Increased nasal epithelial cell responsiveness to IL‐17A in paediatric asthmatics with low blood neutrophil count, low traffic‐related air pollution exposure and good asthma control
Increased nasal epithelial cell responsiveness to IL‐17A in paediatric asthmatics with low blood neutrophil count, low traffic‐related air pollution exposure and good asthma control
Corresponding Author Ian P. Lewkowich Division of Immunobi...
Nitric oxide products and aldehydes in exhaled breath condensate in children with asthma
Nitric oxide products and aldehydes in exhaled breath condensate in children with asthma
Corresponding Author Sara Riscassi sara.riscassi@sabes.it ...
'Practical management of suspected hypersensitivity reactions to anti‐tuberculosis drugs.’
'Practical management of suspected hypersensitivity reactions to anti‐tuberculosis drugs.’
Abstract Tuberculosis (TB) is the commonest cause of death by a single infectious agent globally and ranks amongst the top...
Individual Participant Data Meta‐Analysis versus Aggregate Data Meta‐Analysis: a case study in eczema and food allergy prevention
Individual Participant Data Meta‐Analysis versus Aggregate Data Meta‐Analysis: a case study in eczema and food allergy prevention
Abstract Introduction Meta-analysis traditionally uses aggregate data from published reports. Individual Participant Data ...
Towards the best approach to PEG allergy
Towards the best approach to PEG allergy
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Influence of climate change on airborne pollen concentrations in Madrid, 1979‐2018
Influence of climate change on airborne pollen concentrations in Madrid, 1979‐2018
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Increased Nasal Epithelial Cell Responsiveness to IL‐17A in Pediatric Asthmatics with Low Blood Neutrophil Count, Low Traffic Related Air Pollution Exposure, and Good Asthma Control
Increased Nasal Epithelial Cell Responsiveness to IL‐17A in Pediatric Asthmatics with Low Blood Neutrophil Count, Low Traffic Related Air Pollution Exposure, and Good Asthma Control
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An independent in‐depth analysis proposing adjusted Global Initiative on Asthma (GINA) Step 1‐2 treatment suggestions
An independent in‐depth analysis proposing adjusted Global Initiative on Asthma (GINA) Step 1‐2 treatment suggestions
Abstract The Global initiative on asthma (GINA) strategy included major changes for the treatment of mild asthma in the 20...
Randomized controlled pilot trial with ion‐exchange water softeners to prevent eczema (SOFTER trial)
Randomized controlled pilot trial with ion‐exchange water softeners to prevent eczema (SOFTER trial)
Abstract Background Observational studies suggest an increased risk of eczema in children living in hard versus soft water...
Nitric oxide products and aldehydes in exhaled breath condensate of children with asthma
Nitric oxide products and aldehydes in exhaled breath condensate of children with asthma
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Effect of Acinetobacter lwoffii on the modulation of macrophage activation and asthmatic inflammation
Effect of Acinetobacter lwoffii on the modulation of macrophage activation and asthmatic inflammation
Abstract Background Although lung macrophages are directly exposed to external stimuli, their exact immunologic roles in a...
Frequency of guideline‐defined cow's milk allergy symptoms in infants: Secondary analysis of EAT trial data
Frequency of guideline‐defined cow's milk allergy symptoms in infants: Secondary analysis of EAT trial data
Abstract Background Non-IgE-mediated Cow's Milk Allergy (CMA) has a prevalence of less than 1% in children. Guidelines dev...
Test‐guided dietary exclusions for treating established Atopic Dermatitis in children: A Systematic Review
Test‐guided dietary exclusions for treating established Atopic Dermatitis in children: A Systematic Review
Abstract Atopic Dermatitis (AD), synonymous with Atopic Eczema, is a chronic inflammatory skin disease, characterised by a...
17q12‐q21 variants interact with early‐life exposures to modify asthma risk in Black children
17q12‐q21 variants interact with early‐life exposures to modify asthma risk in Black children
Abstract Genetic factors and early-life exposures1 are both important determinants of childhood asthma. Among the more tha...
Micronutritional supplementation with a holoBLG‐based FSMP (food for special medical purposes)‐lozenge alleviates allergic symptoms in BALB/c mice: Imitating the protective farm effect
Micronutritional supplementation with a holoBLG‐based FSMP (food for special medical purposes)‐lozenge alleviates allergic symptoms in BALB/c mice: Imitating the protective farm effect
Abstract Background Previously, the protective farm effect was imitated using the whey protein beta-lactoglobulin (BLG) th...
Absolute quantification of Bet v 1 in birch polymerized allergenic extracts via mass spectrometry targeted analysis
Absolute quantification of Bet v 1 in birch polymerized allergenic extracts via mass spectrometry targeted analysis
Abstract Background Quantifying major allergens is essential for evaluating the quality and efficacy of allergenic extract...
Specialist allergy advice allows vaccination in patients with reactions to COVID‐19 vaccines
Specialist allergy advice allows vaccination in patients with reactions to COVID‐19 vaccines
Abstract Vaccination remains the most effective means out of the COVID-19 pandemic. Data from randomised clinical trials d...
Revisiting Asian chronic rhinosinusitis in the era of type 2 biologics
Revisiting Asian chronic rhinosinusitis in the era of type 2 biologics
Abstract Chronic rhinosinusitis (CRS) is a highly heterogeneous disorder exhibiting considerable epidemiological, clinical...
Sex‐specific developmental trajectories of eczema from infancy to age 26 years: a birth cohort study
Sex‐specific developmental trajectories of eczema from infancy to age 26 years: a birth cohort study
ABSTRACT Background Eczema is a common inflammatory skin disease with varying developmental trajectories/patterns that are...
Randomised controlled pilot trial with ion‐exchange water softeners to prevent eczema (SOFTER trial)
Randomised controlled pilot trial with ion‐exchange water softeners to prevent eczema (SOFTER trial)
ABSTRACT Background Observational studies suggest an increased risk of eczema in children living in hard versus soft water...
Response to: Allergy societies and the formula industry
Response to: Allergy societies and the formula industry
Abstract In 2020, the BSACI’s policy on how it interacts with industry [1] was ratified at the annual general meeti...
Molecular and immunochemical characterization of Pop n 2: A new allergen of Populus nigra pollen
Molecular and immunochemical characterization of Pop n 2: A new allergen of Populus nigra pollen
Abstract Background Pollen is one of the most common allergens that cause respiratory allergies worldwide. Pollen grains f...
Role of autophagy in regulating interleukin‐10 and the responses to corticosteroids and statins in asthma
Role of autophagy in regulating interleukin‐10 and the responses to corticosteroids and statins in asthma
Abstract Background Interleukin (IL)-10 is a key anti-inflammatory cytokine that may be reduced in asthma but is enhanced ...
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