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When Hormones Attack: A Literature Review of Progesterone-Induced Anaphylaxis
When Hormones Attack: A Literature Review of Progesterone-Induced Anaphylaxis
Progesterone hypersensitivity is a rare and underdiagnosed condition whose incidence is expected to rise due to the increa...
Severe Asthma Patients’ Characteristics in Mexico Versus International Severe Asthma Registry (ISAR) Global
Severe Asthma Patients’ Characteristics in Mexico Versus International Severe Asthma Registry (ISAR) Global
The International Severe Asthma (SA) Registry (ISAR) started in 2017. Mexico joint in 2019. ISAR global patients have been...
Psychophysical Olfactory Outcomes After Biologic Therapy for Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review and Meta-Analysis
Psychophysical Olfactory Outcomes After Biologic Therapy for Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review and Meta-Analysis
Smell loss is among the most debilitating symptoms of chronic rhinosinusitis with nasal polyps (CRSwNP). We aimed to synth...
Understanding Biologics in CRSwNP: Related Events and Insights
Understanding Biologics in CRSwNP: Related Events and Insights
This review examines the immunologic and clinical considerations surrounding biologic therapy for chronic rhinosinusitis w...
A Parade of Persistent and Emerging Contact Allergens – A Clinical Update
A Parade of Persistent and Emerging Contact Allergens – A Clinical Update
Clinical management of allergic contact dermatitis (ACD) is increasingly challenging due to the growing number of allergen...
Current Status of Per- and Poly-Fluoroalkyl Substances (PFAS) Exposure on Lung Cell Biology and Pulmonary Outcomes along Human Health Risk Assessment Steps
Current Status of Per- and Poly-Fluoroalkyl Substances (PFAS) Exposure on Lung Cell Biology and Pulmonary Outcomes along Human Health Risk Assessment Steps
This review aims to summarize the effects of per- and poly-fluoroalkyl substances (PFAS) exposures on the lung, emphasizin...
Epithelial Barrier Dysfunction in Atopic Dermatitis, Allergic Contact Dermatitis, and Chronic Spontaneous Urticaria and its Therapeutic Implications
Epithelial Barrier Dysfunction in Atopic Dermatitis, Allergic Contact Dermatitis, and Chronic Spontaneous Urticaria and its Therapeutic Implications
Allergic skin diseases arise from complex interactions between epithelial barrier dysfunction and immune dysregulation. Th...
Interception of Regulatory RNAs on TGF-β Signaling in the Pathogenesis of Idiopathic Pulmonary Fibrosis: A Systematic Review
Interception of Regulatory RNAs on TGF-β Signaling in the Pathogenesis of Idiopathic Pulmonary Fibrosis: A Systematic Review
Idiopathic Pulmonary Fibrosis is a type of interstitial lung disease characterized by lung scarring due to excessive extra...
The Emerging Role of Ly6G⁺Nur77⁺ Lung Macrophages in Type-2 Allergic Inflammation: A Comprehensive Review on Asthma Pathogenesis
The Emerging Role of Ly6G⁺Nur77⁺ Lung Macrophages in Type-2 Allergic Inflammation: A Comprehensive Review on Asthma Pathogenesis
Asthma remains a major health challenge affecting over 300 million people worldwide, with severe, steroid-resista...
MicroRNAs as current diagnostic biomarkers and potential therapeutic targets in allergic and non-allergic rhinitis – A functional characterization
MicroRNAs as current diagnostic biomarkers and potential therapeutic targets in allergic and non-allergic rhinitis – A functional characterization
Allergic rhinitis affects up to one-quarter of the population in industrialized countries. This chronic inflammatory disea...
Pharmacotherapeutic Medication Adherence in Patients With Allergic Rhinitis: A Systematic Review and Meta-Analysis
Pharmacotherapeutic Medication Adherence in Patients With Allergic Rhinitis: A Systematic Review and Meta-Analysis
Medication adherence is essential for effective management of allergic rhinitis (AR), yet real-world adherence to guidelin...
Impact of IL-4/IL-13 Blockade with Dupilumab on the Microbiome in Type 2 Inflammatory Diseases: A Systematic Review
Impact of IL-4/IL-13 Blockade with Dupilumab on the Microbiome in Type 2 Inflammatory Diseases: A Systematic Review
To systematically review current evidence on microbiota changes associated with dupilumab treatment across different anato...
Correction: Understanding Biologics in CRSwNP: Related Events and Insights
Correction: Understanding Biologics in CRSwNP: Related Events and Insights
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
Understanding Infantile Atopic Dermatitis: A Review of Environmental, Familial, Genetic and Microbial Influences
Understanding Infantile Atopic Dermatitis: A Review of Environmental, Familial, Genetic and Microbial Influences
This review aims to clarify the early-life risk and protective factors associated with Infantile Atopic Dermatitis (IAD)&#...
The Role of the Indoor Exposome in Food Allergy Development
The Role of the Indoor Exposome in Food Allergy Development
Due to the rapid rise in the prevalence of food allergy, environmental exposures, in addition to genetic susceptibility, a...
Targeting Type 2 and Non-type 2 Asthma: Emerging Biologics and Personalized Strategies
Targeting Type 2 and Non-type 2 Asthma: Emerging Biologics and Personalized Strategies
Asthma continues to pose a serious global health issue affecting billions of people and causing significant morbidity. It ...
The Modern Environment and Childhood Asthma: The Role of Air Pollution and Heavy Metal Exposure
The Modern Environment and Childhood Asthma: The Role of Air Pollution and Heavy Metal Exposure
Childhood asthma is the most common chronic non-communicable disease in children and a major global public health challeng...
Incorporating New Guidelines into School-Based Asthma Management
Incorporating New Guidelines into School-Based Asthma Management
The aim of this review is to identify barriers and provide solutions to the implementation of inhaled corticosteroid-formo...
CD8 T Cells You Should Know about in Autoimmunity: Current Paradigms of T Cell Pathogenesis in Autoimmune Disease
CD8 T Cells You Should Know about in Autoimmunity: Current Paradigms of T Cell Pathogenesis in Autoimmune Disease
CD8 T cells comprise a large portion of cells in inflamed tissues in many autoimmune diseases, yet their roles in autoimmu...
Strategies for Tapering the Dosage of Biologics Targeting Type 2 Inflammation: A Systematic Review
Strategies for Tapering the Dosage of Biologics Targeting Type 2 Inflammation: A Systematic Review
This review evaluates current evidence on tapering strategies for anti–type 2 biologics in chronic inflammatory dise...
Traditional Chinese Medicine for Pediatric Allergic Diseases
Traditional Chinese Medicine for Pediatric Allergic Diseases
There is a clinically important and unmet need for long-term safe and effective preventative and therapeutic options for p...
Autoallergy and what the Allergist Needs to know
Autoallergy and what the Allergist Needs to know
This review aims to educate allergists about the concept of autoallergy by addressing five questions: 1) What is autoaller...
Targeting Arginine Metabolism in Immune Cells for the Treatment of Pulmonary Inflammatory Diseases
Targeting Arginine Metabolism in Immune Cells for the Treatment of Pulmonary Inflammatory Diseases
This review aims to provide a comprehensive overview of the role of arginine and its metabolic pathways in regulating immu...
Investigation into the Classification of Cough Sounds for Early Asthma Screening
Investigation into the Classification of Cough Sounds for Early Asthma Screening
This review aims to explore an effective and scalable approach for early asthma detection using cough sounds. The main obj...
The Roles of Acetylcholine and Muscarinic Receptors in Allergic Rhinitis: Mechanisms, Clinical Insights and Future Directions
The Roles of Acetylcholine and Muscarinic Receptors in Allergic Rhinitis: Mechanisms, Clinical Insights and Future Directions
Allergic rhinitis (AR) is a very common and troubling disorder that severely affects patients’ quality of life. Ther...
Lymphoproliferative Disorders Mimicking Rheumatologic Disease: A Clinical Reasoning Perspective
Lymphoproliferative Disorders Mimicking Rheumatologic Disease: A Clinical Reasoning Perspective
Lymphoproliferative disorders encompass a variety of hematologic diseases that are increasingly recognized. Patients with ...
The Effect of Exercise on Asthma in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
The Effect of Exercise on Asthma in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Asthma is a heterogeneous respiratory condition and a common childhood disease. The effects of exercise on childhood asthm...
4-Week Maintenance ICS-Formoterol versus ICS in Adults Newly Diagnosed Mild Asthma: Effects on Symptoms, Lung Function, and Inflammation
4-Week Maintenance ICS-Formoterol versus ICS in Adults Newly Diagnosed Mild Asthma: Effects on Symptoms, Lung Function, and Inflammation
This study aimed to determine whether patients with newly diagnosed mild asthma benefit more from initiating treatment wit...
Detection of Anaphylaxis Through the Cutaneous Barrier
Detection of Anaphylaxis Through the Cutaneous Barrier
The capacity to rapidly and objectively detect impending anaphylaxis is a crucial unmet need in food allergy, as clinical ...
Sarcoidosis in the Genomic Era: From Genetic Drivers to Tailored Therapies
Sarcoidosis in the Genomic Era: From Genetic Drivers to Tailored Therapies
This review aims to synthesize existing literature on the genetics of sarcoidosis, including the genetic architectures ass...
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