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Update on the Pathophysiology and Management of Tics
Update on the Pathophysiology and Management of Tics
This review aims to collate takeaways from the most recent and relevant literature related to tics, from genetic studies t...
Cognition and Long COVID: a Review
Cognition and Long COVID: a Review
Provide an overview of current knowledge regarding cognitive issues in patients with long COVID, also termed brain fog or ...
Recent Advances in Targeted Therapies for Adult Gliomas
Recent Advances in Targeted Therapies for Adult Gliomas
Incorporation of molecular diagnostics has transformed the classification and risk stratification of adult gliomas, reveal...
Amyloid and Tau Co-pathology in Parkinson Disease and Atypical Parkinsonism
Amyloid and Tau Co-pathology in Parkinson Disease and Atypical Parkinsonism
We performed a narrative review of the literature of amyloid and tau co-pathology in Parkinson Disease and atypical parkin...
Preclinical Models of Traumatic Brain Injury: Advances in Models
Preclinical Models of Traumatic Brain Injury: Advances in Models
In vitro traumatic brain injury (TBI) models are invaluable tools for elucidating cellular injury mechanisms and enabling ...
The Effects of Adenosine A1/A3 Receptors Agonist on Improving the Outcomes of TBI and Stroke: Focus on AST-004
The Effects of Adenosine A1/A3 Receptors Agonist on Improving the Outcomes of TBI and Stroke: Focus on AST-004
This review explores the therapeutic potential of dual adenosine A1 and A3 receptor (A1R/A3R) agonism as a neuroprotective...
Redefining Stroke Care with Artificial Intelligence: Recent Advances
Redefining Stroke Care with Artificial Intelligence: Recent Advances
This review aims to provide an overview of how artificial intelligence (AI) is being integrated into stroke care across th...
When is the Radiologically Isolated Syndrome already Multiple Sclerosis According to the 2024 McDonald Criteria?
When is the Radiologically Isolated Syndrome already Multiple Sclerosis According to the 2024 McDonald Criteria?
The McDonald criteria assist neurologists in making accurate and timely diagnoses of multiple sclerosis (MS). The 2024 rev...
Functional and Structural Brain Imaging Correlates of Treatment Response in Functional Movement Disorder
Functional and Structural Brain Imaging Correlates of Treatment Response in Functional Movement Disorder
Functional movement disorder (FMD) is a biopsychosocially-complex condition with diverse neurologic, physical, and psychia...
Astrocytopathy in Wernicke Encephalopathy and Neuromyelitis Optica Spectrum Disorder. Pathogenic Differences With Occasional Clinical and Neuroimaging Overlap. A Review
Astrocytopathy in Wernicke Encephalopathy and Neuromyelitis Optica Spectrum Disorder. Pathogenic Differences With Occasional Clinical and Neuroimaging Overlap. A Review
There is an increasing number of single case reports describing patients with findings compatible with thiamine deficiency...
Mapping the Silent Onset of Parkinson’s Disease: Monoamine Imaging in the Era of the Race for Preclinical Intervention
Mapping the Silent Onset of Parkinson’s Disease: Monoamine Imaging in the Era of the Race for Preclinical Intervention
The main unmet need of Parkinson’s disease (PD) is the lack of a therapy able to slow progression. The field is shif...
The Noradrenergic Brain in Parkinson’s Disease
The Noradrenergic Brain in Parkinson’s Disease
Cerebral noradrenergic activity modulates physiological functions of behaviour, cognition, movement, arousal and sleep. Th...
Drug Treatments for Neurodevelopmental Disorders: Targeting Signaling Pathways and Homeostasis
Drug Treatments for Neurodevelopmental Disorders: Targeting Signaling Pathways and Homeostasis
Preclinical and clinical evidence support the notion that neurodevelopmental disorders (NDDs) are synaptic disorders, char...
Managing Intracranial Pressure Crisis
Managing Intracranial Pressure Crisis
The objective of this review is to provide a comprehensive management protocol for the treatment of intracranial pressure ...
Update on Strategies to Reduce Early Brain Injury after Subarachnoid Hemorrhage
Update on Strategies to Reduce Early Brain Injury after Subarachnoid Hemorrhage
Early brain injury (EBI) after aneurysmal subarachnoid hemorrhage (SAH) is the most influential clinical determinant of ou...
Mobilization in Neurocritical Care: Challenges and Opportunities
Mobilization in Neurocritical Care: Challenges and Opportunities
Mobilization in the Neurological Intensive Care Unit (NICU) significantly improves outcomes and functional recovery while ...
Neuroplasticity in Diffuse Low-grade Gliomas: Backward Modelling of Brain-tumor Interactions Prior to Diagnosis is Needed to Better Predict Recovery after Treatment
Neuroplasticity in Diffuse Low-grade Gliomas: Backward Modelling of Brain-tumor Interactions Prior to Diagnosis is Needed to Better Predict Recovery after Treatment
In low-grade glioma (LGG), besides the patient’s neurological status and tumor characteristics on neuroimaging, curr...
Recent Advances in the Genetics of Ataxias: An Update on Novel Autosomal Dominant Repeat Expansions
Recent Advances in the Genetics of Ataxias: An Update on Novel Autosomal Dominant Repeat Expansions
Autosomal dominant cerebellar ataxias, also known as spinocerebellar ataxias (SCAs), are genetically and clinically divers...
Supporting Long-Term Meaningful Outcomes in Stroke Rehabilitation
Supporting Long-Term Meaningful Outcomes in Stroke Rehabilitation
Rehabilitation is the mainstay of recovery after stroke, but key recommendations focused on delivering ‘as much ther...
The Bidirectional Relationship Between Epilepsy and Alzheimer’s Disease
The Bidirectional Relationship Between Epilepsy and Alzheimer’s Disease
Epilepsy has long been considered a late-stage consequence of Alzheimer’s Disease (AD), but recent studies highlight...
Machine Learning Approaches to Prognostication in Traumatic Brain Injury
Machine Learning Approaches to Prognostication in Traumatic Brain Injury
This review investigates the use of machine learning (ML) in prognosticating outcomes for traumatic brain injury (TBI). It...
Acute Stroke Units Nested within Broader Neurology: Care Bundles for Nursing to Enhance Competence and Interdisciplinary Coordination
Acute Stroke Units Nested within Broader Neurology: Care Bundles for Nursing to Enhance Competence and Interdisciplinary Coordination
The benefits of acute stroke unit care, with nurses as central figures, are well-documented. As care bundles gain traction...
Traumatic Brain Injury and Gut Microbiome: The Role of the Gut-Brain Axis in Neurodegenerative Processes
Traumatic Brain Injury and Gut Microbiome: The Role of the Gut-Brain Axis in Neurodegenerative Processes
A deeper understanding of the communication network between the gut microbiome and the central nervous system, termed the ...
Insights on the Shared Genetic Landscape of Neurodevelopmental and Movement Disorders
Insights on the Shared Genetic Landscape of Neurodevelopmental and Movement Disorders
Large-scale studies using hypothesis-free exome sequencing have revealed the strong heritability of neurodevelopmental dis...
Leptomeningeal Disease: Current Approaches and Future Directions
Leptomeningeal Disease: Current Approaches and Future Directions
Leptomeningeal disease (LMD), or spread of cancer cells into the pia and arachnoid membranes encasing the brain and spinal...
Chronic Neurological Complications of Brain Tumors and Brain Tumor Treatments
Chronic Neurological Complications of Brain Tumors and Brain Tumor Treatments
Chronic complications of brain tumors and brain tumor treatments can lead to impairment of health-related quality of life ...
Neuromodulation for Post-Stroke Motor Recovery: a Narrative Review of Invasive and Non‑Invasive Tools
Neuromodulation for Post-Stroke Motor Recovery: a Narrative Review of Invasive and Non‑Invasive Tools
Stroke remains a leading disabling condition, and many survivors have permanent disability despite acute stroke treatment ...
Neural Control of REM Sleep and Motor Atonia: Current Perspectives
Neural Control of REM Sleep and Motor Atonia: Current Perspectives
Since the formal discovery of rapid eye movement (REM) sleep in 1953, we have gained a vast amount of knowledge regarding ...
Machine Learning and Artificial Intelligence Applications to Epilepsy: a Review for the Practicing Epileptologist
Machine Learning and Artificial Intelligence Applications to Epilepsy: a Review for the Practicing Epileptologist
Machine Learning (ML) and Artificial Intelligence (AI) are data-driven techniques to translate raw data into applicable an...
Exploring the Role of Locus Coeruleus in Alzheimer’s Disease: a Comprehensive Update on MRI Studies and Implications
Exploring the Role of Locus Coeruleus in Alzheimer’s Disease: a Comprehensive Update on MRI Studies and Implications
Performing a thorough review of magnetic resonance imaging (MRI) studies assessing locus coeruleus (LC) integrity in agein...
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