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Cover Image: Entry of the Varicellovirus Canid herpesvirus 1 into Madin–Darby canine kidney epithelial cells is pH‐independent and occurs via a macropinocytosis‐like mechanism but without increase in fluid uptake (Cellular Microbiology 12/2021)
Confocal micrograph showing Canid herpesvirus 1 (red) bound to MDCK cells, and DAPI-stained nuclei (blue). Primary amines ...
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The multiple functions of actin in apicomplexan parasites
Abstract The cytoskeletal protein actin is highly abundant and conserved in eukaryotic cells. It occurs in two different s...
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Vam6/Vps39/TRAP1‐domain proteins influence vacuolar morphology, iron acquisition and virulence in Cryptococcus neoformans
Abstract The pathogenic fungus Cryptococcus neoformans must overcome iron limitation to cause disease in mammalian hosts. ...
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Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane
Abstract Hepatitis B virus (HBV) infection is a major health threat causing 880,000 deaths each year. Available therapies ...
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Chlamydia and HPV induce centrosome amplification in the host cell through additive mechanisms
Abstract Based on epidemiology studies, Chlamydia trachomatis has been proposed as a co-factor for human papillomavirus (H...
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Entry of the varicellovirus Canid herpesvirus 1 into Madin‐Darby canine kidney epithelial cells is pH‐independent and occurs via a macropinocytosis‐like mechanism but without increase in fluid uptake
Abstract Canid herpesvirus 1 (CHV-1) is a Varicellovirus that causes self-limiting infections in adult dogs but morbidity ...
Cellular Microbiology
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Cover Image: The fungivorous amoeba Protostelium aurantium targets redox homeostasis and cell wall integrity during intracellular killing of Candida parapsilosis (Cellular Microbiology 11/2021)
The fungivorous amoeba Protostelium aurantium feeds on a wide range of fungal species. The image shows amoebae digesting G...
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Dengue virus replication enhances labile zinc pools by modulation of ZIP8
Abstract Zinc-dependent viral proteins rely on intracellular zinc homeostasis for successful completion of infectious life...
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Cover Image: Candidalysin delivery to the invasion pocket is critical for host epithelial damage induced by Candida albicans (Cellular Microbiology 10/2021)
Candida albicans hyphae secreting the peptide toxin candidalysin (green) during invasion of epithelial cells. The toxin ac...
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Egress of archaeal viruses
Abstract Viruses of Archaea, arguably the most mysterious part of the virosphere due to their unique morphotypes and genom...
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Blockade of endoplasmic reticulum stress‐induced cell death by Ureaplasma parvum vacuolating factor
Abstract Previously, we found that Ureaplasma parvum internalized into HeLa cells and cytosolic accumulation of galectin-3...
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BSC2 induces multidrug resistance via contributing to the formation of biofilm in Saccharomyces cerevisiae
Abstract Biofilm plays an imoprtant role in fungal multidrug resistance (MDR). Our previous studies showed that BSC2 is in...
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Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through the gingival epithelium via degradation of coxsackievirus and adenovirus receptor
Abstract Porphyromonas gingivalis is a major pathogen of human periodontitis and dysregulates innate immunity at the gingi...
Cellular Microbiology
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The fungivorous amoeba Protostelium aurantium targets redox homeostasis and cell wall integrity during intracellular killing of Candida parapsilosis
Abstract Predatory interactions among microbes are a major evolutionary driving force for biodiversity. The fungivorous am...
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Rickettsia conorii Survival in THP‐1 Macrophages Involves Host Lipid Droplet Alterations and Active Rickettsial Protein Production
Abstract Rickettsia conorii is a Gram-negative, cytosolic intracellular bacterium that has classically been investigated i...
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Zinc finger proteins of Plasmodium falciparum
Abstract Zinc-finger proteins (ZFPs) are a large diverse family of proteins with one or more zinc finger domains in which ...
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Cover Image: Disassembly of the apical junctional complex during the transmigration of Leptospira interrogans across polarized renal proximal tubule epithelial cells (Cellular Microbiology 09/2021)
Focused ion beam-scanning electron microscopy image of renal proximal tubule epithelial cells infected for 24 hrs with Lep...
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Host manipulation by bacterial type III and type IV secretion system effector proteases
Summary Proteases are powerful enzymes, which cleave peptide bonds, leading most of the time to irreversible fragmentation...
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Host cell membrane microdomains and fungal infection
Abstract Lipid microdomains or lipid rafts are dynamic and tightly ordered regions of the plasma membrane. In mammalian ce...
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Mucosal immune responses in the trachea after chronic infection with Mycoplasma gallisepticum in unvaccinated and vaccinated mature chickens
Abstract Tracheitis associated with the chronic respiratory disease in chickens caused by Mycoplasma gallisepticum is mark...
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