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Antimicrobial use on Campylobacter revealed by next-generation sequencing in patients with common variable immunodeficiency
Because few studies have focused on recurrent Campylobacter bacteremia, we investigated two clinical cases of patients wit...
The enhancing therapeutic effect of neonatal jaundice by bifidobacterium through regulating inflammation and gut microbiota in combination with phototherapy—a randomized controlled trial
BackgroundHyperbilirubinemia is among the most common conditions in neonates, and phototherapy is currently the most widel...
Qifuyin improves physiological frailty by regulating the intestinal flora in 3xTg-AD mice
ObjectiveAlzheimer’s disease (AD) is often accompanied by motor dysfunction, impaired limb strength, and gut microbiota di...
Rhizospheric soil microbial community structure and metabolic characteristics of wild Cymbidium mastersii at different altitudes
IntroductionCymbidium mastersii, a perennial orchid of high ornamental value, faces severe survival challenges due to extr...
Elephant-derived Bacillus licheniformis modulates immune cells shedding light on cancer resistance
IntroductionColorectal cancer (CRC) is currently a leading cause of cancer-related morbidity and mortality globally, under...
Integrative transcriptomic meta-analysis reveals conserved transcriptional signatures and predictive biomarkers for active tuberculosis: a pathway-based machine learning approach
BackgroundTuberculosis (TB) caused 1.23 million deaths in 2024, with accurate diagnosis hampered by population heterogenei...
Humoral immunity and infection status of PLWH following vaccination after the BA.5/BF.7 wave
ObjectivesTo ensure adequate preparedness of immunocompromised populations for future pandemic waves, it is crucial to ass...
Correction: Microbiome-inspired solutions to save human and planetary health
In the acknowledgements, [The TU Graz Open Access Publishing Fund that supported the Open Acess Publication Fund was not i...
Bacillus megaterium supplementation improves growth performance, immunity, antioxidant capacity, and gut microbiota in cold-stressed neonatal calves
IntroductionNeonatal calves exhibit immature digestive and immune systems, rendering them susceptible to environmental str...
Genomics, transcriptomics, and laboratory experiments link bioconvection to nitrogen fixation
IntroductionLake Cadagno is a meromictic lake characterized by a stable euxinic chemocline that hosts a diverse community ...
Red root rot alters root-zone microbial communities and enzyme activities in Hevea brasiliensis
IntroductionThe rubber tree (Hevea brasiliensis) is an important industrial raw material and strategic resource in China. ...
H-phosphinic analogs of natural amino acids: a novel and efficient treatment for preventing biodeterioration of treasured painted artworks
IntroductionMicroorganisms can destroy various materials that make up objects of cultural heritage. In particular, ancient...
Chromosome-scale genome assembly of Naematelia sinensis (Jin Er mushroom) offers new insights into the distinct mating-type genomes feature and genome evolution
Naematelia sinensis (Jin Er mushroom) is a gelatinous fungus of significant economic and medicinal value indigenous to Chi...
Description and complete genome sequence of Mycobacterium venezuelense sp. nov., a rapidly growing species recovered from a soft tissue infection
We describe a rapidly growing mycobacterial (RGM) species closely related to Mycobacterium wolinskyi. The bacterium was is...
Unveiling pathogens and contaminants: refining metagenomics for clinical diagnostics
IntroductionShotgun metagenomic sequencing (mNGS), an untargeted approach that sequences all nucleic acids in a sample, ha...
Combination antibiotic therapy is required to eliminate Bartonella henselae in multiple microenvironments
Bartonella are gram-negative, facultative intracellular bacteria. Infection by Bartonella manifests as different clinical ...
Detection and genetic characterization of atypical porcine pestivirus in wild boars in European Russia
Atypical porcine pestivirus (APPeV), currently known as Pestivirus scrofae, is common in domestic pigs of many countries i...
Limits of rapid diagnostics: genomic and structural insights into OXA-48–like mediated carbapenem resistance in Escherichia coli
Carbapenem-resistant Escherichia coli (CREC) represent a major clinical threat because of limited treatment options and fr...
Exploring the potential of oxymatrine in preventing CHIKV-induced acute kidney injury based on multi-dimensional computational analysis and in vitro experiments
Chikungunya virus (CHIKV) infection can induce acute kidney injury (AKI) and may be fatal in severe cases, yet effective t...
Genomic characterization of ceftazidime/avibactam-resistant Klebsiella pneumoniae: a retrospective analysis on clinical isolates from an Italian transplant unit
IntroductionKlebsiella pneumoniae infections are a significant healthcare concern due to advancing antimicrobial resistanc...
A human monoclonal antibody isolated from Japanese encephalitis virus vaccine-vaccinated volunteer neutralizing various flaviviruses
Introduction Flaviviruses are positive-sense, single-stranded RNA viruses that include dengue virus (DV, classified into...
WhiA transcription factor provides feedback loop between translation and energy production in a genome-reduced bacterium
1 Introduction The regulation of housekeeping gene expression in simple organisms is of particular interest in synthetic...
Microbial optimization for improved charring of agricultural solid waste: a cutting-edge technology across the life cycle
The resource utilization of agricultural solid waste plays a crucial role in environmental pollution prevention and agricu...
Evolution of community-associated MRSA: a 20-year genomic and epidemiological study in Region Örebro County, Sweden
Introduction The opportunistic gram-positive bacterium Staphylococcus aureus is one of the most common infectious agents ...
Can there be calm during a cytokine storm? Immune checkpoint pathways affecting the severity of COVID-19 disease
Introduction The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2...
Deciphering dengue: novel RNA barcoding segments for enhanced serotype-specific identification and global surveillance of dengue viruses
Highlights • We standardized the framework for RNA barcoding technology and optimized the existing barcode segment valida...
Physiological and intestinal microbiota responses of sea cucumber Apostichopus japonicus to various stress and signatures of intestinal microbiota dysbiosis
1 Introduction As the global population continues to rise and the demand for sustainable aquaculture increases, the indu...
An experimental chimeric hepatitis E virus vaccine elicits both local and systemic immune responses
1 Introduction The hepatitis E virus (HEV) is a causative agent of hepatitis, responsible for 20 million infections and ...
Antibiotic legacies shape the temperature response of soil microbial communities
1 Introduction Soil ecosystems are impacted by multiple anthropogenic stressors: agricultural management and intensifica...
Meta-analysis of gut microbiota alterations in patients with irritable bowel syndrome
1 Introduction Irritable bowel syndrome (IBS) is a prototypical psychosomatic condition of the digestive system, closely...
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