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Synergistic Interactions Between the Quinolone-Derived Compound HT61 and Tobramycin Against a Range of Clinical Isolates of In Vitro
Synergistic Interactions Between the Quinolone-Derived Compound HT61 and Tobramycin Against a Range of Clinical Isolates of In Vitro
Antimicrobial-resistant pathogens such as Pseudomonas aeruginosa (P. aeruginosa) represent a significant challeng...
COPD Patients on Inhaled Corticosteroids Managed in Primary Care: Proportion of Patients Potentially Eligible for Biologic Therapy
COPD Patients on Inhaled Corticosteroids Managed in Primary Care: Proportion of Patients Potentially Eligible for Biologic Therapy
Christenson SA, Smith BM, Bafadhel M, Putcha N (2022) Chronic obstructive pulmonary disease. Lancet 399(10342):2227–2242. ...
Prevalence of Laryngeal Abnormal Sensation in a Hospital Worker Population and its Association with Cough Hypersensitivity
Prevalence of Laryngeal Abnormal Sensation in a Hospital Worker Population and its Association with Cough Hypersensitivity
Cough hypersensitivity is characterized by exaggerated cough responses to mild stimuli, which is frequently associated wit...
State of the Art Review: Glucagon-Like Peptide-1 in Obesity-Related Asthma
State of the Art Review: Glucagon-Like Peptide-1 in Obesity-Related Asthma
Asthma is a heterogeneous condition characterized by chronic airway inflammation, airway hyperresponsiveness, and mucin hy...
Acute Right Ventricular Failure in the Medical ICU
Acute Right Ventricular Failure in the Medical ICU
Right ventricular failure (RVF) is a complex clinical syndrome resulting from anatomical and physiological dysfunction of ...
A Prospective Study of Safety and the Incremental Diagnostic Value of Transbronchial Cryobiopsy Incorporated into Robotic-Assisted Bronchoscopy in a Cancer Population
A Prospective Study of Safety and the Incremental Diagnostic Value of Transbronchial Cryobiopsy Incorporated into Robotic-Assisted Bronchoscopy in a Cancer Population
Shape-sensing robotic-assisted bronchoscopy (ssRAB) combined with intraoperative imaging optimizes tool-lesion relationshi...
Four Methods to Determine Expiratory Time Constants from Spirometry and Their Sensitivity to Detect Airway Obstruction
Four Methods to Determine Expiratory Time Constants from Spirometry and Their Sensitivity to Detect Airway Obstruction
The expiratory time constant (TC), reflecting the rate of lung emptying, has emerged as a marker of early small airway dis...
Sputum Eosinophils Predict Annual Remission of the Frequent Exacerbator Phenotype in COPD: A Prospective Cohort Study
Sputum Eosinophils Predict Annual Remission of the Frequent Exacerbator Phenotype in COPD: A Prospective Cohort Study
The frequent-exacerbator (FE) phenotype guides COPD management, yet its year-to-year stability and the role of airway eosi...
Stratified Comparison of Risk Factors for Mild Versus Moderate-to-Severe Bronchopulmonary Dysplasia in Very Preterm Infants (< 32 Weeks Gestational Age)
Stratified Comparison of Risk Factors for Mild Versus Moderate-to-Severe Bronchopulmonary Dysplasia in Very Preterm Infants (< 32 Weeks Gestational Age)
Bronchopulmonary dysplasia (BPD) remains a significant complication in very preterm infants (&lt; 32 weeks gesta...
Oxygen Saturation Sample Entropy, a Novel Diagnostic Tool in Sleep Disordered Breathing
Oxygen Saturation Sample Entropy, a Novel Diagnostic Tool in Sleep Disordered Breathing
To assess whether a Network Physiology approach using Sample Entropy and Transfer Entropy can be applied to simple physiol...
Sputum from Individuals with Primary Ciliary Dyskinesia Drives M2-like Macrophage Polarization
Sputum from Individuals with Primary Ciliary Dyskinesia Drives M2-like Macrophage Polarization
Primary ciliary dyskinesia (PCD) is a rare, congenital condition in which impaired ciliary function leads to bronchiectasi...
HU308, A Selective Cannabinoid Type-2 Receptor Agonist, Mitigates SARS-CoV-2 Spike Protein–Induced Acute Lung Injury in Mice
HU308, A Selective Cannabinoid Type-2 Receptor Agonist, Mitigates SARS-CoV-2 Spike Protein–Induced Acute Lung Injury in Mice
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ...
Repetitive Exposure to Nicotine-Free Vaping Impairs Airway Defences and Delays Recovery
Repetitive Exposure to Nicotine-Free Vaping Impairs Airway Defences and Delays Recovery
E-cigarette use, or vaping, is increasing in prevalence, especially among adolescents. There is a paucity of information o...
Clinical History, Spirometry, and CT Features Can Predict Dyspnea in Smokers with and without Spirometry-Defined COPD
Clinical History, Spirometry, and CT Features Can Predict Dyspnea in Smokers with and without Spirometry-Defined COPD
Dyspnea is common in smokers with or without chronic obstructive pulmonary disease. Its multifactorial nature makes it cha...
Longitudinal Multimodal Assessment of Pulmonary Nodules in Fibrosing Interstitial Lung Diseases: A Retrospective Study
Longitudinal Multimodal Assessment of Pulmonary Nodules in Fibrosing Interstitial Lung Diseases: A Retrospective Study
Pulmonary nodules are increasingly detected during high-resolution computed tomography (HRCT) surveillance in patients wit...
Mechanisms of Anti-Oxidants, N-Acetylcysteine and Elamipretide (SS-31), on Ozone-Induced Airway Hyperresponsiveness and Mucus Hypersecretion
Mechanisms of Anti-Oxidants, N-Acetylcysteine and Elamipretide (SS-31), on Ozone-Induced Airway Hyperresponsiveness and Mucus Hypersecretion
Ozone (O₃) exposure induces acute airway injury characterized by airway hyperresponsiveness (AHR) and airway mucus h...
Impact of Asthma and Obstructive Sleep Apnea on Central Airways Resistance During Pregnancy
Impact of Asthma and Obstructive Sleep Apnea on Central Airways Resistance During Pregnancy
Pregnancy is a risk factor for the development of obstructive sleep apnea (OSA) and for worsening of asthma; the interacti...
Roles of Pyruvate Kinase M2 in Pulmonary Diseases: What Do We Know So Far?
Roles of Pyruvate Kinase M2 in Pulmonary Diseases: What Do We Know So Far?
Pyruvate kinase M2 (PKM2) is a critical enzyme regulating cell metabolism and growth under different physiological conditi...
Overexpression of BPIFB4 Alleviates COPD Inflammatory Damage by Inhibiting M1 Macrophage Activation via the PI3K/AKT Pathway
Overexpression of BPIFB4 Alleviates COPD Inflammatory Damage by Inhibiting M1 Macrophage Activation via the PI3K/AKT Pathway
Macrophage polarization is essential for inflammatory regulation in COPD. The precise role of BPI Fold-Containing Family B...
Genetic Factors Explain Half of the Individual Susceptibility to Chronic Bronchitis, Airflow Obstruction and COPD Regardless of the Spirometric Definition: A Nationwide Twin Study
Genetic Factors Explain Half of the Individual Susceptibility to Chronic Bronchitis, Airflow Obstruction and COPD Regardless of the Spirometric Definition: A Nationwide Twin Study
Smoking is a major risk factor for lung function decline and chronic obstructive pulmonary disease (COPD), but the individ...
Right Ventricular-Pulmonary Arterial Uncoupling Thresholds in Acute Pulmonary Embolism
Right Ventricular-Pulmonary Arterial Uncoupling Thresholds in Acute Pulmonary Embolism
Right ventricle (RV) dysfunction in the setting of acute pulmonary embolism (PE) is associated with worse outcomes. The ra...
The Advantages of FEV Percent Predicted Change During Bronchial Challenge Testing
The Advantages of FEV Percent Predicted Change During Bronchial Challenge Testing
The methacholine challenge requires a 20% fall in forced expiratory volume in one second (FEV1). The fall is measured as l...
Prophylactic Inhaled Antibiotics for Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis of Incidence and Mortality Outcomes
Prophylactic Inhaled Antibiotics for Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis of Incidence and Mortality Outcomes
Ventilator-associated pneumonia (VAP) is a common ICU complication linked to high morbidity and mortality. Inhaled antibio...
Cmpk2 Protects Against Acute Lung Injury in Mice
Cmpk2 Protects Against Acute Lung Injury in Mice
Acute respiratory distress syndrome (ARDS)/Acute lung injury (ALI), characterized by severe hypoxemia and pulmonary edema,...
Electronic-Nose Technology for Lung Cancer Detection: A Non-Invasive Diagnostic Revolution
Electronic-Nose Technology for Lung Cancer Detection: A Non-Invasive Diagnostic Revolution
Lung cancer (LC) remains a leading cause of cancer-related mortality worldwide, primarily due to late-stage diagnosis and ...
Effectiveness of Nintedanib in Progressive Pulmonary Fibrosis Assessed by Progression Criteria: An Italian, Observational, Multicenter Study
Effectiveness of Nintedanib in Progressive Pulmonary Fibrosis Assessed by Progression Criteria: An Italian, Observational, Multicenter Study
Pulmonary fibrosis is defined as progressive based on the combination of radiological, clinical, and functional criteria. ...
Use of Telomere Length as a Biomarker in Idiopathic Pulmonary Fibrosis
Use of Telomere Length as a Biomarker in Idiopathic Pulmonary Fibrosis
Telomere shortening, a hallmark of cellular aging, is associated with poor outcomes in idiopathic pulmonary fibrosis (IPF)...
Soluble Transferrin Receptor-1 in Pulmonary Hypertension Associated with COPD
Soluble Transferrin Receptor-1 in Pulmonary Hypertension Associated with COPD
The pulmonary vascular involvement of COPD ranges from severe airway obstruction without pulmonary hypertension (PH) to mi...
From Glucotoxicity to Lung Injury: Emerging Perspectives on Diabetes-Associated Respiratory Complications
From Glucotoxicity to Lung Injury: Emerging Perspectives on Diabetes-Associated Respiratory Complications
Emerging evidence highlights glucose toxicity as a pivotal driver of diabetic respiratory complications, characterized by ...
ICD-10 Diagnostic Coding Patterns and Clinical Correlates in Refractory Chronic Cough: Analysis from the Korean Chronic Cough Registry
ICD-10 Diagnostic Coding Patterns and Clinical Correlates in Refractory Chronic Cough: Analysis from the Korean Chronic Cough Registry
The International Classification of Diseases (ICD) system plays a key role in health data classification but currently lac...
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