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Emergence and genetic heterogeneity of STEC O113:H4: insights from whole-genome sequences of isolates across human and non-human sources
Volume 321, December 2025, 151688Author links open overlay panel, , , , , , , , , , , , AbstractThe increased detection of...
A pan-azole and pan-echinocandin resistant Wickerhamomyces anomalus isolate causing bloodstream infection: ERG11Y140F, K151R with copy number variation and FKS1 F665S mutation
Fungal infections pose a growing global threat, particularly due to the emergence of multidrug-resistant pathogens. This s...
Multiple isolation of ST398/t011 MRSA from patients in the first half of 2025 in Imam Reza Hospital, Bojnurd, North Eastern Iran
IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) remains a global health threat, with livestock-associated (...
Stability of Clostridioides difficile toxins in stool samples
Clostridioides difficile infection (CDI) is mediated by the cytotoxins TcdA and/or TcdB. The reliable detection of these t...
Metabolite-responsive regulator RpiRB modulates Staphylococcus aureus pathogenicity via regulation of agr expression
Staphylococcus aureus is a well-known pathogenic bacterium that can produce a variety of virulence factors that cause dise...
Epidemiology of gonococcal arthritis in Brittany - France (EpGAr study)
BackgroundGonococcal infections are sexually-transmitted infections (STIs), which in 0.5–3 % of cases, can progress to dis...
Lactobacillus gasseri suppresses the Helicobacter pylori-induced expression of the proliferation-associated factors HBEGF and TGF-α in gastric host cells
To date, various probiotic lactobacilli have been tested against Helicobacter pylori. However, a detailed molecular analys...
Dehydroeffusol from Juncus effusus L. exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus in vitro and in vivo
BackgroundDehydroeffusol (DHE) is a natural phenanthrene compound derived from Juncus effusus L., traditionally used for i...
The substrate-binding protein DppA modulates the virulence of hypervirulent Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae (hvKp), one of the most significant pathogens in nosocomial infections, regulates the ...
Comparative genomic analysis of cyclomodulin-producing Escherichia coli strains of animal origin
Cytolethal distending toxin (CDT), a cyclomodulin and genotoxin produced by many Gram-negative bacteria including pathogen...
Epidemiology of multidrug resistant E. coli isolates from a German university hospital illustrates dominance of E. coli ST131
Our study characterized 301 extended-spectrum beta-lactamases (ESBL) Escherichia coli isolates collected a tertiary hospit...
Sequence variability of Hungarian RSV G and F proteins between 2017 and 2023: single-center study
Our study determined the prevalence, types of RSV, and sequence variability of the G and F genes in Hungary between 2017 a...
Clinical utility of bronchoalveolar lavage fluid metagenomic next-generation sequencing in the etiological diagnosis of community-acquired pneumonia in children
CAP is a major cause of pediatric hospitalization on a global scale, particularly in developing countries where the morbid...
Genomic comparison of Leptospira interrogans isolated from humans, dogs, and wild and feral animals in Japan
Leptospirosis, caused by pathogenic Leptospira spp., is one of the most prevalent zoonotic diseases worldwide. While whole...
Travel associated human coccidioidomycosis in Germany 2011–2023
This study reviews proven coccidioidomycosis cases in Germany associated with travel between 2011 and 2023 to endemic regi...
Targeting fimbriae adhesin of porcine enterotoxigenic Escherichia coli by isoliquiritigenin
Enterotoxigenic Escherichia coli (ETEC), a predominant pathogen responsible for neonatal animal diarrhea, poses a signific...
Resistome, virulome and mobilome of clinical carbapenemase-producing Acinetobacter baumannii strains isolated in Togo
Genomics have become crucial in addressing the public health challenges posed by antimicrobial resistance (AMR). In this s...
Characterization and antibiofilm efficacy of the Pseudomonas aeruginosa phage HKPH_J3
In recent years, due to the spread of antibiotic resistance, Pseudomonas aeruginosa has emerged as an ESKAPE super-resista...
Transcriptomic and functional evidence reveals dual-module immune response of human-nasal staphylococcus aureus in Koi Carp (Cyprinus carpio)
Staphylococcus aureus is a significant pathogen that poses a threat to both human and animal health. Its pathogenicity in ...
mNGS-guided precision management of M. pneumoniae pneumonia: Pathogen load assessment and fungal co-detection patterns directing antibiotic optimization
BackgroundGlobal Mycoplasma pneumoniae pneumonia (MPP) outbreaks show increasing refractory cases. Conventional diagnostic...
Carbon source utilization in hybrid Shiga toxin-producing and uropathogenic Escherichia coli indicates uropathogenic origin
Volume 319, June 2025, 151653Author links open overlay panel, , , AbstractTo investigate the adaptation of hybrid Escheric...
DDX17 promotes DENV-2 replication via interaction with viral dsRNA and G3BP1
Dengue virus (DENV) is one of the major arboviruses that pose a serious threat to global human health. However, there is c...
Characterization of outer membrane vesicles of Aggregatibacter actinomycetemcomitans serotypes a, b and c and their interactions with human neutrophils
Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative oral pathogen associated with periodontitis and systemic dis...
Assessing potential misidentification of Staphylococcus argenteus as Staphylococcus aureus in clinical routine samples: A retrospective study
Staphylococcus argenteus is a recently described member of the Staphylococcus aureus complex. Thus far, its frequency in c...
Occurrence of vanA/vanM-positive vancomycin-resistant Enterococcus faecium in hospital wastewater associated with clinical infections in Guangzhou, China: A genomic epidemiological study
BackgroundThe emerging ST80 vancomycin-resistant Enterococcus faecium (VREfm) lineage, linked to the increases of clinical...
From crisis to routine – Standardization of SARS-CoV-2 genome detection by enhanced EQA schemes in a scientific pandemic network
Volume 319, June 2025, 151656Author links open overlay panel, , , , , , , , , , , , , , , , , , , …AbstractIn the beginnin...
Enteropathogenic Escherichia coli revisited – New insights into old EPEC isolates using whole genome sequencing
Volume 320, September 2025, 151659Author links open overlay panel, , , , , , AbstractEnteropathogenic E. coli (EPEC) cause...
Helicobacter pylori CagT4SS proteins CagN and CagM bind DNA and CagN is involved in heptose-independent pro-inflammatory substrate translocation by the T4SS
The Cag type 4 secretion system (CagT4SS) of Helicobacter pylori is encoded on the cag pathogenicity island (cagPAI) that ...
Association between hospital onset of infection and outcomes in sepsis patients – a propensity score matched cohort study based on health claims data in Germany
Association between hospital onset of infection and outcomes in sepsis patients – a propensity score matched cohort study based on health claims data in Germany
Available online 1 December 2023, 151593Author links open overlay panel, , , , , , , , , , , AbstractBackgroundHospital-ac...
Past and present seroprevalence and disease burden estimates of Toxoplasma gondii infections in Germany: an appreciation of the role of serodiagnostics
Past and present seroprevalence and disease burden estimates of Toxoplasma gondii infections in Germany: an appreciation of the role of serodiagnostics
Available online 1 December 2023, 151592Author links open overlay panelAbstractToxoplasmosis is one of the major foodborne...
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