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Heart Failure with Preserved Ejection Fraction as a Risk Factor for Atrial Fibrillation Recurrence after Ablation
Heart Failure with Preserved Ejection Fraction as a Risk Factor for Atrial Fibrillation Recurrence after Ablation
Atrial fibrillation (AF) recurrence after radiofrequency ablation is closely associated with patient prognosis, while the ...
Mitochondria at the Heart of Ischemia-Reperfusion (I/R) Injury: the HOXB5-Sirt5 Axis
Mitochondria at the Heart of Ischemia-Reperfusion (I/R) Injury: the HOXB5-Sirt5 Axis
Ischemic cardiomyopathy (ICM) arises from restricted myocardial blood flow, leading to ischemia/reperfusion (I/R) injury, ...
Protective Effects of Jiawei Baihu Tang in Kawasaki Disease: Omics Analysis and Mechanistic Exploration
Protective Effects of Jiawei Baihu Tang in Kawasaki Disease: Omics Analysis and Mechanistic Exploration
Kawasaki disease (KD) is classified as a “WenBing” syndrome in traditional Chinese medicine (TCM), characteriz...
Targeting SIRT3 in Diabetic Cardiomyopathy: Mechanism-Based Therapeutic Strategies
Targeting SIRT3 in Diabetic Cardiomyopathy: Mechanism-Based Therapeutic Strategies
Diabetic cardiomyopathy (DCM) represents a prevalent and clinically significant complication associated with diabetes mell...
Lipoprotein (a) and Coronary Atherosclerosis in Intracoronary Imaging - YELLOW II – Lp(a) Study
Lipoprotein (a) and Coronary Atherosclerosis in Intracoronary Imaging - YELLOW II – Lp(a) Study
We aimed to evaluate associations between lipoprotein (a) [Lp(a)] levels and intravascular imaged coronary lesions morphol...
Hyperuricemia and Hypoxic Pulmonary Hypertension: Pathogenic Links, Clinical Evidence, and Emerging Therapeutic Insights
Hyperuricemia and Hypoxic Pulmonary Hypertension: Pathogenic Links, Clinical Evidence, and Emerging Therapeutic Insights
This review aims to explore the role of hyperuricemia in the pathogenesis of hypoxic pulmonary hypertension (HPH), focusin...
Molecular Interplay of Gene Network Dynamics, Epigenetic Regulation, and Therapeutic Mapping in Cardiovascular Disease
Molecular Interplay of Gene Network Dynamics, Epigenetic Regulation, and Therapeutic Mapping in Cardiovascular Disease
Cardiovascular diseases (CVDs) continue to be the leading cause of death globally, driven by a complex interplay of geneti...
Direct Oral Anticoagulants in Valvular Diseases and Prosthetic Valves: Why Not?
Direct Oral Anticoagulants in Valvular Diseases and Prosthetic Valves: Why Not?
Valvular heart disease (VHD) and atrial fibrillation (AF) often coexist and lead to a prothrombotic state that necessitate...
The Emerging Role of Lactate and Lactylation Modifications in the Pathophysiology of Atherosclerotic Cardiovascular Diseases
The Emerging Role of Lactate and Lactylation Modifications in the Pathophysiology of Atherosclerotic Cardiovascular Diseases
Atherosclerosis is a chronic disease that is characterized by lipid accumulation and inflammation in the arterial wall. At...
Resuscitative Mean Arterial Pressure Targets in Cardiovascular Disease: A Narrative Review of Clinical Outcomes
Resuscitative Mean Arterial Pressure Targets in Cardiovascular Disease: A Narrative Review of Clinical Outcomes
Mean arterial pressure (MAP) is a commonly used hemodynamic proxy for tissue perfusion. Continuous MAP monitoring and main...
GLP1-RA and SGLT2-i: Implementation and Insulin Deescalation Strategies
GLP1-RA and SGLT2-i: Implementation and Insulin Deescalation Strategies
This review will summarize the most contemporary trials for glucagon-like peptide 1 receptor agonists (GLP1-RA) and sodium...
Real-World Efficacy of Inclisiran in Veneto Region (Italy): The INCLIVEN Multicenter Registry
Real-World Efficacy of Inclisiran in Veneto Region (Italy): The INCLIVEN Multicenter Registry
Inclisiran is a long-acting small interfering RNA (siRNA) which prevents the synthesis of PCSK9 in hepatocytes, reducing L...
AGE-RAGE Axis and Cardiovascular Diseases: Pathophysiologic Mechanisms and Prospects for Clinical Applications
AGE-RAGE Axis and Cardiovascular Diseases: Pathophysiologic Mechanisms and Prospects for Clinical Applications
Advanced glycation end products (AGE), a diverse array of molecules generated through non-enzymatic glycosylation, in conj...
Epicardial Adipocytes in Cardiac Pathology and Healing
Epicardial Adipocytes in Cardiac Pathology and Healing
Implications of epicardial adipose tissue (EAT) on the development of coronary artery disease (CAD) have garnered recent a...
Associations of SGLT2i with Cardiorenal Outcomes Among Diabetics with Prostate Cancer on Hormone Therapy
Associations of SGLT2i with Cardiorenal Outcomes Among Diabetics with Prostate Cancer on Hormone Therapy
Studies have reported associations between prostate cancer, type II diabetes mellitus (T2DM), and cardiovascular disease i...
Ticagrelor versus Clopidogrel: Two Controversial Drugs in Patients with Acute Coronary Syndrome
Ticagrelor versus Clopidogrel: Two Controversial Drugs in Patients with Acute Coronary Syndrome
Yan Y, Xu H, Zhao Y, Lin S, Zheng Y. Ticagrelor versus clopidogrel in patients with left main coronary artery stenting. Ca...