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Transthyretin Kinetic Stabilizers for ATTR Amyloidosis: A Narrative Review of Mechanisms and Therapeutic Benefits
Transthyretin Kinetic Stabilizers for ATTR Amyloidosis: A Narrative Review of Mechanisms and Therapeutic Benefits
Transthyretin amyloidosis (ATTR amyloidosis) is a systemic disease affecting multiple organ systems, particularly the hear...
Incomplete Right Bundle Branch Block: A Narrative Review of Clinical Relevance, Diagnostic Pitfalls, and Prognostic Implications
Incomplete Right Bundle Branch Block: A Narrative Review of Clinical Relevance, Diagnostic Pitfalls, and Prognostic Implications
Incomplete right bundle branch block (iRBBB) is a frequent electrocardiographic (ECG) finding, often considered benign. Ho...
Real-World Safety and Effectiveness of Evolocumab in Korean Patients with Atherosclerotic Cardiovascular Disease or Familial Hypercholesterolemia: A Post-Marketing Surveillance Study
Real-World Safety and Effectiveness of Evolocumab in Korean Patients with Atherosclerotic Cardiovascular Disease or Familial Hypercholesterolemia: A Post-Marketing Surveillance Study
The efficacy and safety of evolocumab have been established in clinical trials. This post-marketing surveillance (PMS) stu...
Hitting the Sweet Spot: A Review of SGLT2i in Cardiovascular Medicine
Hitting the Sweet Spot: A Review of SGLT2i in Cardiovascular Medicine
Sodium–glucose cotransporter 2 inhibitors (SGLT2i) are a class of medications initially developed for glyce...
Resistant Blood Pressure: New Frontiers in Interventional Hypertension Therapy
Resistant Blood Pressure: New Frontiers in Interventional Hypertension Therapy
Hypertension remains a leading global health challenge, affecting over 1.3 billion individuals worldwide and contributing ...
Treatment Patterns and Healthcare Resource Utilization Among Patients with Obstructive Hypertrophic Cardiomyopathy in Japan: A Claims Database Study
Treatment Patterns and Healthcare Resource Utilization Among Patients with Obstructive Hypertrophic Cardiomyopathy in Japan: A Claims Database Study
Obstructive hypertrophic cardiomyopathy (HCM) increases the risk of developing cardiac complications and can impact long-t...
Impact of Office and Ambulatory Blood Pressure on Mortality in Patients with Coronary Heart Disease
Impact of Office and Ambulatory Blood Pressure on Mortality in Patients with Coronary Heart Disease
There is scarce evidence on the prognostic impact of ambulatory blood pressure monitoring (ABPM) in patients with coronary...
Reverse Takotsubo Cardiomyopathy After an Adverse Reaction to Alteplase Treated with Intravenous Epinephrine
Reverse Takotsubo Cardiomyopathy After an Adverse Reaction to Alteplase Treated with Intravenous Epinephrine
Takotsubo (stress) cardiomyopathy (TTC) is an uncommon acute heart failure syndrome characterized by transient hypocontrac...
Real-World Adherence and Effectiveness of Inclisiran in Lowering LDL-C: Results from 1 Year of Follow-Up
Real-World Adherence and Effectiveness of Inclisiran in Lowering LDL-C: Results from 1 Year of Follow-Up
Atherosclerotic cardiovascular disease (ASCVD) is a global health concern. Reducing low-density lipoprotein cholesterol (L...
Impella vs. IABP in Non-emergent High-Risk PCI: Outcomes and LVEF Recovery from a Large US EHR Study
Impella vs. IABP in Non-emergent High-Risk PCI: Outcomes and LVEF Recovery from a Large US EHR Study
High-risk percutaneous coronary intervention (HR-PCI) involves patients with complex coronary disease, adverse hemodynamic...
Colchicine Among Patients with Acute Coronary Syndrome: A Meta-Analysis of Randomized Trials
Colchicine Among Patients with Acute Coronary Syndrome: A Meta-Analysis of Randomized Trials
Prior trials evaluating the benefit of colchicine in patients with acute coronary syndrome (ACS) have yielded mixed result...
Functionally Limiting Symptoms and Inability to Independently Complete Daily Activities Increase the Burden Felt by Caregivers to Patients with ATTR-CM
Functionally Limiting Symptoms and Inability to Independently Complete Daily Activities Increase the Burden Felt by Caregivers to Patients with ATTR-CM
The Burden of Disease survey characterized the humanistic burden of transthyretin amyloid cardiomyopathy (ATTR-CM) in 208 ...
Real-World Outcomes Among Patients in the United States Receiving Tafamidis for Transthyretin Amyloid Cardiomyopathy
Real-World Outcomes Among Patients in the United States Receiving Tafamidis for Transthyretin Amyloid Cardiomyopathy
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, often fatal disease. Tafamidis demonstrated efficacy in A...
Study Design and Baseline Characteristics of the VERINA Study: Phase IV Evidence of Vericiguat for Worsening Heart Failure Management
Study Design and Baseline Characteristics of the VERINA Study: Phase IV Evidence of Vericiguat for Worsening Heart Failure Management
Patients with heart failure with reduced ejection fraction (HFrEF) experience higher rates of in-hospital and all-cause mo...
Prognostic Role of the PRECISE-DAPT Score in Acute Coronary Syndrome and Different Antithrombotic Treatment Strategies
Prognostic Role of the PRECISE-DAPT Score in Acute Coronary Syndrome and Different Antithrombotic Treatment Strategies
The PRECISE-DAPT score is a useful tool for predicting the risk of bleeding after percutaneous coronary intervention (PCI)...
In-Hospital and 1-Year Outcomes of Octogenarian and Nonagenarian Patients with Severely Calcified Coronary Lesions Treated with Rotational Atherectomy
In-Hospital and 1-Year Outcomes of Octogenarian and Nonagenarian Patients with Severely Calcified Coronary Lesions Treated with Rotational Atherectomy
Severely calcified coronary lesions are a common challenge in older percutaneous coronary intervention (PCI) populations. ...
Effectiveness and Tolerability of Trimetazidine 80 mg Once Daily in Patients with Chronic Coronary Syndrome in Brazil: The V-GOOD Observational Study
Effectiveness and Tolerability of Trimetazidine 80 mg Once Daily in Patients with Chronic Coronary Syndrome in Brazil: The V-GOOD Observational Study
The V-GOOD study evaluated the effectiveness of trimetazidine modified-release (MR) 80 mg once daily (OD) in pati...
Arterial Hypertension and Associated Risk Factors in Kazakhstan: An Analysis of Blood Pressure Screening Results from May Measurement Month 2021–2023
Arterial Hypertension and Associated Risk Factors in Kazakhstan: An Analysis of Blood Pressure Screening Results from May Measurement Month 2021–2023
May Measurement Month (MMM) is a global campaign with the aim to improve awareness of arterial hypertension (AH). Kazakhst...
Effect of Mavacamten on Echocardiographic Features in Chinese Patients with Obstructive Hypertrophic Cardiomyopathy: Results from the EXPLORER-CN Study
Effect of Mavacamten on Echocardiographic Features in Chinese Patients with Obstructive Hypertrophic Cardiomyopathy: Results from the EXPLORER-CN Study
Mavacamten, a cardiac myosin inhibitor, has demonstrated positive outcomes in left ventricular outflow tract (LVOT) gradie...
Efficacy and Safety of the Fixed-Dose Combination of Atorvastatin/Fenofibrate Versus Atorvastatin on the Lipid Profile of Patients with Type 2 Diabetes and Dyslipidemia
Efficacy and Safety of the Fixed-Dose Combination of Atorvastatin/Fenofibrate Versus Atorvastatin on the Lipid Profile of Patients with Type 2 Diabetes and Dyslipidemia
In dyslipidemia associated with type 2 diabetes (T2DM), elevated triglycerides (TG), increased low-density lipoprotein cho...
Left Ventricular Mechanical Circulatory Support Devices for Cardiogenic Shock After Myocardial Infarction
Left Ventricular Mechanical Circulatory Support Devices for Cardiogenic Shock After Myocardial Infarction
Cardiogenic shock is the most common cause of mortality in patients with acute myocardial infarction (AMI). Historically, ...
Patient Experience of Heart Disease with Elevated Lipoprotein(a): Views from a Patient, His Physician, and a Patient Association
Patient Experience of Heart Disease with Elevated Lipoprotein(a): Views from a Patient, His Physician, and a Patient Association
This article presents three points of view on lipoprotein(a) [Lp(a)]: that of a patient, his endocrinologist, and a patien...
An External Control Arm for the Oral Factor XIa Inhibitor Asundexian Phase 2 Trial in Atrial Fibrillation (PACIFIC-AF) Using Electronic Health Records
An External Control Arm for the Oral Factor XIa Inhibitor Asundexian Phase 2 Trial in Atrial Fibrillation (PACIFIC-AF) Using Electronic Health Records
The aim of this study was to assess the applicability of an external control arm (ECA) approach in the clinical developmen...
Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Polyvascular Disease
Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Polyvascular Disease
There is a paucity of data regarding the trends and comparative outcomes of transcatheter aortic valve replacement (TAVR) ...
Safety and Efficacy of Tafamidis in Chinese Patients with Transthyretin Amyloid Cardiomyopathy
Safety and Efficacy of Tafamidis in Chinese Patients with Transthyretin Amyloid Cardiomyopathy
Tafamidis is approved in many countries for the treatment of patients with transthyretin amyloid cardiomyopathy (ATTR-CM)....
Correction: Rationale and Design of ANTHOLOGY: An ATTR Amyloidosis Real-World Evidence Program Aiming to Address Gaps in Amyloidosis Care
Correction: Rationale and Design of ANTHOLOGY: An ATTR Amyloidosis Real-World Evidence Program Aiming to Address Gaps in Amyloidosis Care
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International ...
Association Between Insulin Resistance and Incomplete Endothelization of LAAC Devices in Patients with Atrial Fibrillation: A Retrospective Study
Association Between Insulin Resistance and Incomplete Endothelization of LAAC Devices in Patients with Atrial Fibrillation: A Retrospective Study
Incomplete endothelialization (IDE) of left atrial appendage closure (LAAC) devices increases the risk of device-related t...
Cracking the Zip Code: Uncovering the Link Between Socioeconomic Status and Transcatheter Aortic Valve Replacement Outcomes
Cracking the Zip Code: Uncovering the Link Between Socioeconomic Status and Transcatheter Aortic Valve Replacement Outcomes
There is a well-known correlation between lower socioeconomic status and health outcomes. Patient zip codes and the Center...
Safety and Effectiveness of Apixaban in Very Elderly Patients with Atrial Fibrillation: A Retrospective Analysis of Japanese Administrative Claims Data
Safety and Effectiveness of Apixaban in Very Elderly Patients with Atrial Fibrillation: A Retrospective Analysis of Japanese Administrative Claims Data
Anticoagulation is a well-established treatment for patients with atrial fibrillation (AF) for the prevention of stroke/sy...
Survival in a Contemporary, Real-World Cohort of Patients with Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy Treated with Tafamidis: An Analysis from THAOS
Survival in a Contemporary, Real-World Cohort of Patients with Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy Treated with Tafamidis: An Analysis from THAOS
Tafamidis is approved to treat transthyretin amyloid cardiomyopathy (ATTR-CM). Many patients with ATTR-CM present with a m...
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