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Complement inhibitor therapy should be available to patients with paroxysmal nocturnal hemoglobinuria throughout the world
Complement inhibitor therapy should be available to patients with paroxysmal nocturnal hemoglobinuria throughout the world
The development of several complement-inhibiting medicines has been a major advance in the management of paroxysmal noctur...
Real-world effectiveness of fostamatinib in patients with immune thrombocytopenia: a single-center retrospective study
Real-world effectiveness of fostamatinib in patients with immune thrombocytopenia: a single-center retrospective study
Immune thrombocytopenia (ITP) is an acquired autoimmune disease characterized by increased platelet destruction and thromb...
Beyond nuclear export: chromatin-bound XPO1/CRM1 as a transcriptional scaffold
Beyond nuclear export: chromatin-bound XPO1/CRM1 as a transcriptional scaffold
XPO1/CRM1 (also known as Exportin-1) is best known as a RanGTP-dependent nuclear export receptor and has been explored as ...
Metabolic mimic of inherited bone marrow failure: LMBRD1 (cblF) deficiency in an infant
Metabolic mimic of inherited bone marrow failure: LMBRD1 (cblF) deficiency in an infant
Disorders of intracellular cobalamin metabolism are rare but treatable conditions that mimic bone marrow failure syndromes...
Dimensionality reduction enables MRD visualization in single-sample flow cytometric analysis in acute leukemia
Dimensionality reduction enables MRD visualization in single-sample flow cytometric analysis in acute leukemia
Minimal/measurable residual disease (MRD) analysis using multiparametric flow cytometry (MFC-MRD) is essential for therapy...
Timing of autologous stem cell transplantation and induction response in central nervous system lymphoma
Timing of autologous stem cell transplantation and induction response in central nervous system lymphoma
Primary and secondary central nervous system lymphomas (PCNSL and SCNSL, respectively) are aggressive non-Hodgkin lymphoma...
99mTc-HSA scintigraphy identifies protein-losing enteropathy in atypical GI-GVHD with modest diarrhea after allo-HSCT
99mTc-HSA scintigraphy identifies protein-losing enteropathy in atypical GI-GVHD with modest diarrhea after allo-HSCT
Protein-losing enteropathy (PLE) is an uncommon but clinically important manifestation of gastrointestinal graft-versus-ho...
Baseline plasma EBV-DNA load as an adjunctive biomarker for refractory or recurrent disease in pediatric EBV-HLH
Baseline plasma EBV-DNA load as an adjunctive biomarker for refractory or recurrent disease in pediatric EBV-HLH
Quantitative Epstein–Barr virus (EBV)-DNA measurement is used in EBV-associated hemophagocytic lymphohistiocytosis (...
Umbilical cord blood-derived CAR-NK cells: an emerging off-the-shelf platform for cancer immunotherapy
Umbilical cord blood-derived CAR-NK cells: an emerging off-the-shelf platform for cancer immunotherapy
Autologous CAR-T therapy has achieved notable success in B-cell malignancies, yet its broader application is constrained b...
Belumosudil for acute GVHD after allogeneic hematopoietic stem cell transplantation: a retrospective case series
Belumosudil for acute GVHD after allogeneic hematopoietic stem cell transplantation: a retrospective case series
Current therapies for acute graft-versus-host disease (aGVHD) are limited by suboptimal efficacy or excessive immunosuppre...
Association of carotid intima media thickness with cardiovascular disease risk in immune thrombocytopenia
Association of carotid intima media thickness with cardiovascular disease risk in immune thrombocytopenia
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by reduced platelet count, associated with both an i...
Road to treatment-free remission in chronic myeloid leukemia
Road to treatment-free remission in chronic myeloid leukemia
The development of BCR::ABL1 tyrosine kinase inhibitors (TKIs) has transformed chronic myeloid leukemia into a chronic dis...
Venetoclax-based combination regimens for therapy-related myeloid neoplasms
Venetoclax-based combination regimens for therapy-related myeloid neoplasms
Therapy-related myeloid neoplasms (t-MN) are an aggressive and heterogeneous group of myeloid disorders with no establishe...
Safety and effectiveness of lisocabtagene maraleucel following PD-1 blockade in relapsed or refractory PMBCL
Safety and effectiveness of lisocabtagene maraleucel following PD-1 blockade in relapsed or refractory PMBCL
Primary mediastinal B-cell lymphoma (PMBCL) is a distinct subtype of large B-cell lymphoma characterized by 9p24.1 copy-nu...
A phase I/II study of tagraxofusp in Japanese patients with blastic plasmacytoid dendritic cell neoplasm
A phase I/II study of tagraxofusp in Japanese patients with blastic plasmacytoid dendritic cell neoplasm
Tagraxofusp (TAG), a first-in-class CD123-targeted therapy, is a recombinant fusion protein of human interleukin-3 conjuga...
Prognostic factors influencing outcomes of allogeneic HCT for AML with monosomal karyotype
Prognostic factors influencing outcomes of allogeneic HCT for AML with monosomal karyotype
Monosomal karyotype (MK) comprises chromosomal abnormalities defined as either one single autosomal monosomy with structur...
Cutaneous T-cell lymphoma in Kuwait: a retrospective analysis of treatment modalities and prognostic factors
Cutaneous T-cell lymphoma in Kuwait: a retrospective analysis of treatment modalities and prognostic factors
Cutaneous T-cell lymphoma (CTCL) is a rare malignancy with limited data available from the Middle East. This study evaluat...
Viral-driven oncogenesis in T/NK-cell lymphomas: parallels and divergences between HTLV-1 and EBV
Viral-driven oncogenesis in T/NK-cell lymphomas: parallels and divergences between HTLV-1 and EBV
Viruses induce approximately 12% of human cancers, including lymphomas. In the case of T/NK cell neoplasms, human T-cell l...
Three-year follow-up of epcoritamab therapy in Japanese patients with relapsed/refractory follicular lymphoma in EPCORE NHL-3
Three-year follow-up of epcoritamab therapy in Japanese patients with relapsed/refractory follicular lymphoma in EPCORE NHL-3
The CD3xCD20 bispecific antibody epcoritamab demonstrated deep, durable responses with manageable safety in relapsed/refra...