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– Where are we at?
– Where are we at?
This review outlines trends and impact of antimicrobial resistance (AMR) on management strategies for Mycoplasma genitaliu...
CRISPR Applications in HIV Management – Prevention, Diagnosis, Monitoring and Treatment
CRISPR Applications in HIV Management – Prevention, Diagnosis, Monitoring and Treatment
Despite global efforts to combat the human immunodeficiency virus (HIV) epidemic, acquired immunodeficiency syndrome (AIDS...
Geospatial Approaches to HIV Care: a Scoping Review of Asset Mapping
Geospatial Approaches to HIV Care: a Scoping Review of Asset Mapping
Asset mapping aims to engage members of a community to explore and map assets that are solutions to social issues such as ...
Herpes Simplex Virus Type 2 Screening in Persons with and Without HIV: Evidence, Challenges, and Future Directions
Herpes Simplex Virus Type 2 Screening in Persons with and Without HIV: Evidence, Challenges, and Future Directions
Herpes simplex virus type 2 (HSV-2) infection is one of the most prevalent sexually transmitted infections worldwide, with...
Cytotoxic CD4 T Cells: Dual Agents in HIV-1 Pathogenesis and Persistence
Cytotoxic CD4 T Cells: Dual Agents in HIV-1 Pathogenesis and Persistence
Cytotoxic CD4 T cells (CD4 CTL) have long been recognized for their potentially protective role in people with HIV, but on...
Cytomegalovirus in HIV: A Modifiable Driver of Inflammation, Frailty, and Aging
Cytomegalovirus in HIV: A Modifiable Driver of Inflammation, Frailty, and Aging
Cytomegalovirus (CMV) infection is nearly universal among people with HIV (PWH) and contributes to chronic inflammation, i...
Effect of Timing and Duration of ART on the Composition of HIV Reservoirs: Implications for HIV Cure Strategies
Effect of Timing and Duration of ART on the Composition of HIV Reservoirs: Implications for HIV Cure Strategies
Antiretroviral therapy (ART) has transformed HIV from a fatal disease into a manageable condition by effectively suppressi...
T-Cell Profiles in HBV Functional Cure and People Living With HIV: Known Knowns, Known Unknowns, and Unknown Unknowns
T-Cell Profiles in HBV Functional Cure and People Living With HIV: Known Knowns, Known Unknowns, and Unknown Unknowns
HIV further complicates the already complex clinical course of chronic HBV infection. Here we present a personal view of t...
The Implications of HIV-1 Subtypes on Pathogenesis, Reservoirs and Cure Strategies
The Implications of HIV-1 Subtypes on Pathogenesis, Reservoirs and Cure Strategies
The HIV-1 pandemic is characterized by extensive viral genetic diversity, with strains that can be classified into distinc...
Epigenetic aging is a hallmark of HIV pathogenesis and phenotypic outcomes
Epigenetic aging is a hallmark of HIV pathogenesis and phenotypic outcomes
To provide a summary of epigenetic studies of HIV with a focus on DNA methylation-based biomarkers of aging. We examine fi...
Central Nervous System HIV Persistence and Clinical Consequences During Suppressive ART
Central Nervous System HIV Persistence and Clinical Consequences During Suppressive ART
This review discusses recent advances in understanding the mechanisms of CNS HIV invasion and persistence and examines how...
HIV-1 Tat-driven Glutamate Dysregulation: Implications for Cognitive Impairment in HAND
HIV-1 Tat-driven Glutamate Dysregulation: Implications for Cognitive Impairment in HAND
HIV-1-associated neurocognitive disorders (HAND) manifest in 15% to 50% of people with HIV, impairing learning and memory ...
HIV Reservoirs in Brain parenchyma and Cerebrospinal Fluid During Suppressive ART: Same-Same or Very Different?
HIV Reservoirs in Brain parenchyma and Cerebrospinal Fluid During Suppressive ART: Same-Same or Very Different?
The central nervous system (CNS) remains a relatively understudied reservoir of HIV that may have significant implications...
Improving Communication: A Narrative Synthesis of Interventions for HIV Disclosure to Pediatric Populations
Improving Communication: A Narrative Synthesis of Interventions for HIV Disclosure to Pediatric Populations
HIV remains a significant global public health concern, affecting millions worldwide, including children. Disclosure of HI...
Enhancing HIV Prevention Efforts in the Criminal Legal System: A Comprehensive Review and Recommendations
Enhancing HIV Prevention Efforts in the Criminal Legal System: A Comprehensive Review and Recommendations
Despite encouraging declines in the overall rate of new transmission globally, HIV prevention efforts targeting individual...
The Role of Liver Biopsy and Fine Needle Aspiration in Novel HBV Therapeutics in HIV and HBV Coinfection
The Role of Liver Biopsy and Fine Needle Aspiration in Novel HBV Therapeutics in HIV and HBV Coinfection
Liver biopsy and FNA in persons with HIV-HBV coinfection can aid in the assessment of intrahepatic milieu, direct function...
Current and Investigational Biomarkers of Liver Disease in HIV-HBV Co-infection
Current and Investigational Biomarkers of Liver Disease in HIV-HBV Co-infection
Coinfection with HIV-HBV results in increased rate of liver disease progression through immune and metabolic dysfunction. ...
Current Tools to Diagnose and Predict Hepatocellular Carcinoma: Relevance to HIV and Hepatitis B Virus Coinfection
Current Tools to Diagnose and Predict Hepatocellular Carcinoma: Relevance to HIV and Hepatitis B Virus Coinfection
People with HIV and HBV coinfection have increased risk of developing liver fibrosis and hepatocellular carcinoma (HCC) co...
The Role of Integrated HBV DNA in the Quest for a Cure in HIV/HBV co-infection
The Role of Integrated HBV DNA in the Quest for a Cure in HIV/HBV co-infection
This review highlights the importance of Hepatitis B virus (HBV) integrated into the host genome (iDNA) to functional cure...
Digital Interventions for Stimulant Use Among People Living with HIV: A Narrative Review
Digital Interventions for Stimulant Use Among People Living with HIV: A Narrative Review
Stimulant use, which includes use of cocaine and methamphetamine, is known to worsen care outcomes among people living wit...
Innate Immune Cell Functions Contribute to Spontaneous HIV Control
Innate Immune Cell Functions Contribute to Spontaneous HIV Control
To review the role of innate immune cells in shaping the viral reservoir and maintenance of long-term viral control of spo...
Understanding the Drivers of CAB PrEP Uptake and Use among Women in sub-Saharan Africa to Build Demand for New PrEP Methods
Understanding the Drivers of CAB PrEP Uptake and Use among Women in sub-Saharan Africa to Build Demand for New PrEP Methods
As injectable cabotegravir for pre-exposure prophylaxis (CAB PrEP) is introduced in sub-Saharan Africa, it is important to...
Intestinal Microbiota and Aging in People with HIV—What We Know and What We Don’t
Intestinal Microbiota and Aging in People with HIV—What We Know and What We Don’t
People with HIV (PWH) experience premature aging and an elevated risk of age-related comorbidities, even with viral suppre...
Disruptions to HIV Prevention During Armed Conflict in Ukraine and Other Settings
Disruptions to HIV Prevention During Armed Conflict in Ukraine and Other Settings
This review evaluates recent literature to understand the ways in which war disrupts HIV prevention and creates conditions...
Update on Vaccination Recommendations for Adults with HIV
Update on Vaccination Recommendations for Adults with HIV
Vaccination recommendations for people with HIV (PWH) differ from the general population given potential for diminished im...
Cannabis Use in HIV: Impact on Inflammation, Immunity and the Microbiome
Cannabis Use in HIV: Impact on Inflammation, Immunity and the Microbiome
This review explores how cannabis impacts the gut microbiome, immune system, and ART outcomes in people with HIV (PWH). Gi...
Implementation Strategies for Digital HIV Prevention and Care Interventions for Youth: A Scoping Review
Implementation Strategies for Digital HIV Prevention and Care Interventions for Youth: A Scoping Review
Despite the proliferation of evidence-based digital HIV prevention and care interventions for youth globally, their implem...