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SCI Abstract
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Analysis of the Economic and Public Health Impact of New Immunization Strategies in Infants Against Respiratory Syncytial Virus (RSV) in Colombia
Respiratory syncytial virus (RSV) infections are a leading cause of lower respiratory tract infections (LRTI), particularl...
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Effectiveness of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People with HIV on Any Antiretroviral Therapy Regimen: The Retrospective ESSENTIAL Study
Real-world evidence on the effectiveness and durability of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) a...
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Comparison of the Hospital Burden Associated with Respiratory Syncytial Virus and Human Metapneumovirus Across All Age Groups in Scotland: A Retrospective Analysis
Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are commonly associated with respiratory tract infectio...
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Hospitalisation Burden of Human Metapneumovirus and Respiratory Syncytial Virus in Adults by Age and Comorbidity Status in Scotland: A Retrospective Analysis
Respiratory syncytial virus (RSV) is well recognised as an important contributor to respiratory tract infections (RTIs) in...
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Global Viral Lower Respiratory Disease Episodes, Hospitalisations, and Clinical Outcomes by Aetiology, 2010–2021
Viral lower respiratory tract disease (LRTD) is a major cause of global morbidity and mortality, but pathogen-specific est...
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Impact of Switching from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide or Entecavir in Older Patients with Chronic Hepatitis B
Tenofovir disoproxil fumarate (TDF) is highly effective for chronic hepatitis B (CHB) but may induce progressive ...
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Cost-Effectiveness of Bivalent Respiratory Syncytial Virus Prefusion F Vaccine for Older Adults in the Netherlands
Lower respiratory tract disease caused by respiratory syncytial virus (RSV-LRTD) is associated with substantial clinical a...
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The Impact of Influenza on Health-Related Quality of Life, Work Productivity, and Activity Impairment Among Symptomatic US Patients with Influenza
Evidence on the impact of influenza on health-related quality of life (HRQoL) and work productivity and activity impairmen...
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Immunogenicity, Tolerability, and Safety of BA.1-Adapted BNT162b2 Vaccine in 18- to 55-Year-Olds Previously Vaccinated with BNT162b2 or Who Were COVID-19 Vaccine-Naive
Variant-adapted COVID-19 vaccines can induce more robust immune responses against closely matched circulating variants tha...
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Early Warning and Behavioural Intervention on the Cardiovascular Disease Risk in People Living with HIV: A Multicentre Non-Randomized Controlled Trial
Human Immunodeficiency Virus (HIV) infection has currently become a manageable chronic disease with the prevalence of anti...
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Real-World Effectiveness of Ceftazidime–Avibactam for Multidrug-Resistant Gram-Negative Pneumonia, Time-Stratified Risk Factors for Short- and Long-Term Mortality, and Inpatient Costs: A Multicenter Retrospective Cohort Study
Multidrug-resistant (MDR) Gram-negative pneumonia is associated with high mortality and substantial healthcare resource ut...
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A Phase IIa, Proof-of-Concept, Placebo-Controlled, Randomised Trial to Investigate the Efficacy and Safety of Oxfendazole as a Macrofilaricidal Drug in Adults Harbouring Lymphatic Filarial Worms
Lymphatic filariasis (LF) remains a significant public health concern, with India contributing nearly 55% of the global di...
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Elevated Plasma GDF-15 Levels are Associated with the Immune Non-Responder Phenotype in People with HIV
Most people with HIV (PWH) achieve immune recovery with antiretroviral therapy (ART); however, a clinically relevant subse...
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Can We Compare Adverse Event’s Attributable Risk Using a Self-Controlled Case Series Design for Vaccine Safety? A Guillain-Barré Syndrome Use Case
Estimating attributable risk (AR) through self-controlled case series (SCCS) analyses alone may limit generalizability bec...
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Clinical Research on Microecological Landscape for Infection Risk Stratification in Newly Diagnosed Patients with Hematological Conditions
Infection is a common and potentially fatal complication during the treatment of hematological diseases, particularly in t...
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Cost-Effectiveness Analysis of Aztreonam–Avibactam Compared with Colistin Plus Meropenem in Treating Metallo-Beta-Lactamase-Producing Enterobacterales Infections in Spain
Aztreonam–avibactam (ATM-AVI) is the first β-lactam/β-lactamase inhibitor antibiotic for treating serious ...
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How to Better Screen for Blood-Borne Viruses, Specifically HIV, in Hospital Emergency Departments: French and European Perspectives
Hospital emergency departments (EDs) represent an acceptable and economically viable source of data on screening for blood...
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Acute and Long-Term Healthcare Utilization and Expenditures for Serious Bacterial Infections among Newborns in US Hospitals
Serious bacterial infections among newborns are associated with significant morbidity, mortality, and economic costs. Whil...
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Understanding the Epidemiology and Contributing Factors of Post-COVID-19 Pertussis Outbreaks: A Narrative Review
Pertussis or whooping cough, caused by the bacteria Bordetella pertussis, is a highly contagious respiratory dise...
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The Structure, Properties, and Clinical Utility of Contezolid for Antituberculosis: A Narrative Review
Tuberculosis (TB) continues to represent a significant global public health concern, with China being a country that bears...
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Impact of Risk Stacking on COVID-19–Related Healthcare Utilization: A Real-World Retrospective Cohort Study
This study evaluated the impact of “risk stacking” on COVID-19–related hospitalizations, emergency depar...
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Chest Computed Tomography Patterns Associated with Severity in Adults with Respiratory Syncytial Virus Infection: A Retrospective Cohort Study
There are limited data available on the relationship between chest computed tomography (CT) patterns and clinical severity...
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A Review of Doxycycline Post-Exposure Prophylaxis and Its Implications for Antimicrobial Resistance and the Human Microbiome
Sexually transmitted infections (STIs) remain a major global health burden, with rising incidence of Neisseria gonorrhoeae...
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Estimating the Health and Economic Burden of Pneumococcal Diseases Attributable to PCV21 Versus PCV20 or PPSV23 Serotypes Among Adults in Norway
Routine childhood immunization programs using pneumococcal conjugate vaccines (PCVs) significantly reduce the burden of pn...
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Seven versus Fourteen Days of Antibiotics for Gram-Negative Bacteremia from a Urinary Tract Source: a Systematic Review and Meta-analysis
The optimal duration of antibiotic therapy for Gram-negative bacteremia sourced from urinary tract infections (UTI) remain...
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Molecular Epidemiology of Methicillin-Resistant Causing Healthcare-Associated Bloodstream Infections in Brazil: Results from A Prospective Countrywide Multicenter Study
The molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) impact transmission, clinical presenta...
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Long-Term Antibody Persistence After Hepatitis A Vaccination in Healthy Toddlers: Insights from Modeling
Argentina was the first South American country to adopt a single-dose hepatitis A vaccine for 1-year-old children, replaci...
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Hepatitis A to E in People with HIV: A Virus-Specific Review of Prevention and Treatment
People with HIV (PWH) are disproportionately affected by viral hepatitis as a result of overlapping transmission routes, r...
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The Cefazolin Inoculum Effect: An Underappreciated Factor in MSSA Treatment Strategies
Methicillin-susceptible Staphylococcus aureus (MSSA) remains a major cause of morbidity and mortality worldwide, particula...
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Meningococcal Disease in Older Adults: Challenges in Diagnosis and Management
Invasive meningococcal disease (IMD) in older adults frequently presents with atypical clinical manifestations, including ...
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