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SCI Abstract
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Live microbials to boost Anti-SARS-CoV-2 immunity clinical trial (Live BASIC trial): a triple-blind randomized controlled trial
With waning immunity and vaccine hesitancy, the COVID-19 pandemic continues to pose risks. A live microbial consortium (OL...
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Cerebrospinal fluid findings and their temporal pattern in patients with different clinical presentations of tick-borne encephalitis; a cohort study
There is a lack of systematic data on cerebrospinal fluid (CSF) findings in the different clinical manifestations of tick-...
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Pathogen identification and outcome in adult patients with community-acquired pneumonia in Switzerland: findings from the Swiss CAPNETZ cohort study
Community-acquired pneumonia (CAP) causes significant morbidity and mortality, but Swiss data are limited. We analyzed the...
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Melioidosis imported to Northern Germany: a case report series
Melioidosis is a serious infection caused by Burkholderia pseudomallei, a bacterium found in soil, water, and plants in tr...
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Chronic carriers and multidrug resistance in typhoid fever: pathogenesis, challenges, and integrated control strategies
Typhoid fever, a systemic disease caused by Salmonella enterica serovar Typhi (S. Typhi), remains a major global health pr...
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Think sepsis, write sepsis, code sepsis – patient characteristics associated with sepsis (under-)coding in administrative health data
Sepsis is a leading cause of morbidity and mortality, yet its documentation and coding in administrative health data remai...
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Epidemiological profile of causative agents in nosocomial pneumonia: a four-year multicenter surveillance study from Georgia (2020–2023)
Nosocomial pneumonia (NP), including hospital-acquired (HAP) and ventilator-associated pneumonia (VAP), remains a leading ...
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Definitional ambiguity and the dual threat of Hypervirulent infections: a systematic review and meta-analysis
Hypervirulent Klebsiella pneumoniae (HvKp) causes severe invasive infections, but the lack of a standardized definition co...
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Effectiveness of antibiotic prophylaxis for ventilator-associated pneumonia in acute brain injury: a systematic review and meta-analysis
Ventilator-associated pneumonia (VAP) affects 30–50% of mechanically ventilated patients with acute brain injury (AB...
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Universal opt-in HIV, HBV and HCV testing in an emergency department: implementation and outcomes of a comprehensive screening program
To evaluate a Blood Born Virus (BBV) infection screening program in an emergency department (ED) located in an urban setti...
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HIV-1 virologic failure in the RESINA cohort: lessons from two decades of real-world data
To quantify virologic failure (VF), identify predictors, characterize resistance patterns at failure, and evaluate time to...
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Unmasking the mimic: vertebral alveolar echinococcosis diagnosed by metagenomic next-generation sequencing
A Siberian woman in her forties presented to a public hospital in northeastern Germany with chronic back pain and a parave...
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Efficacy, immunogenicity, and safety of typhoid conjugate vaccines in children and adolescents: a systematic review and meta-analysis
Typhoid is a serious infectious disease that is highly prevalent in low and middle income countries (LMICs) and causes sev...
Infection
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Evaluating the health economic impact of cefepime/enmetazobactam in complicated urinary tract infections in the German setting: a cost analysis from payer perspective
Complicated urinary tract infections (cUTIs) are ubiquitous, associated with healthcare resources, and demand effective an...
Infection
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Oral antibiotics demonstrate similar rates of success and complications compared to parenteral antibiotics for bone and joint infections: a systematic review and meta-analysis
Bone and joint infections (BJIs) cause significant morbidity, and current guidelines suggest treatment with parenteral ant...
Infection
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Vibrio fluvialis cholangitis with bacteremia and refractory septic shock: a case report and review of the literature
Vibrio fluvialis is an emerging pathogen primarily associated with gastroenteritis, though an increasing number of extrain...
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Cervical infection in a patient with lymphadenitis and previously unknown anti-IFN-γ IgG autoantibodies
Infections with atypical mycobacteria are rare and sometimes difficult to correctly diagnose. In many cases underlying dis...
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Unusual case of non-sexual Mpox transmission in a heterosexual woman
Monkeypox (MPOX) is becoming an important differential diagnosis in non-endemic regions, particularly in patients with aty...
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Impact of sarcopenia and obesity on mortality in older adults with SARS-CoV-2 infection: automated deep learning body composition analysis in the NAPKON-SUEP cohort
Severe respiratory infections pose a major challenge in clinical practice, especially in older adults. Body composition an...
Infection
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A very rare case of osseous involvement of the dens axis in a 52-year-old HIV positive patient as part of secondary syphilis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Infection
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Cellulosimicrobium cellulans endocarditis: a challenge for detection and treatment in interdisciplinary teams
We present a case of subacute endocarditis with the detection of Cellulosimicrobium cellulans after tricuspid valve replac...
Infection
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infection: a rare case of resistance to amphotericin b following traumatic intracranial injury in an 18-month-old boy
Nucci M, Anaissie E. Fusarium infections in immunocompromised patients. Clin Microbiol Rev. 2020;33(3):e00112–20. ...
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Diagnosis, management and prevention of loiasis: guideline of the German Society for Tropical Medicine, Travel Medicine, and Global Health (DTG)
Loiasis is a complex filarial infection endemic in Central Africa and parts of West Africa. Loa loa is transmitted by the ...
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A large outbreak of multiple serovars linked to alfalfa sprouts in Norway, October to December 2024
This study investigates a nationwide Salmonella outbreak in Norway during October–December 2024 involving four diffe...
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Suspected Buruli ulcer cases in Tonkolili District, Sierra Leone– a prospective cohort study
There is a high burden of chronic ulcers in Sierra Leone. However, (early) diagnosis and treatment are challenging. Data o...
Infection
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Meropenem plasma concentrations in critically ill patients treated with the novel multi organ replacement therapy ADVOS
Optimal dosing of antibiotics in critically ill patients treated with the novel multi organ replacement therapy ADVOS (ADV...
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Predictors of mortality of enterococcal bacteraemia and the role of source control interventions; a retrospective cohort study
To identify predictors of mortality among patients with enterococcal bacteraemia. This retrospective study was conducted a...
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Antigen-specific chemokine CCL3 as a biomarker for distinguishing between recent and remote tuberculosis infection
Identifying recent tuberculosis (TB) infection individuals and administering TB preventive therapy (TPT) are critical stra...
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Micro- and nanoplastics reduce the phagocytosis and intracellular killing of by THP1-Blue™ NFκB monocytes
Micro- and nanoplastic particles occur ubiquitously in the environment and have been detected in various organs in animals...
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Bridging oral and systemic health: exploring pathogenesis, biomarkers, and diagnostic innovations in periodontal disease
This narrative review explores the multifaceted links between periodontal diseases (gingivitis and periodontitis) and syst...
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