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Proceedings of the 2026 North American Society of Head and Neck Pathology Companion Meeting, San Antonio, TX, March 22, 2026: It’s a Trap!: Diagnostic Pitfalls in Sinonasal Pathology
Proceedings of the 2026 North American Society of Head and Neck Pathology Companion Meeting, San Antonio, TX, March 22, 2026: It’s a Trap!: Diagnostic Pitfalls in Sinonasal Pathology
Sinonasal pathology presents unique diagnostic challenges due to the anatomic complexity of the region, the wide histologi...
p63-Positive Diffuse Large B-cell Lymphoma of Oropharynx: A Treacherous Mimic of HPV-Related Squamous Cell Carcinoma—A Report of Three Cases
p63-Positive Diffuse Large B-cell Lymphoma of Oropharynx: A Treacherous Mimic of HPV-Related Squamous Cell Carcinoma—A Report of Three Cases
Human papillomavirus-associated squamous cell carcinoma is the most common malignant neoplasm of the oropharynx, often exp...
Intraductal Salivary Gland Neoplasms of the Oral Cavity: A Retrospective Case Series with Emphasis on Newly Described Entities
Intraductal Salivary Gland Neoplasms of the Oral Cavity: A Retrospective Case Series with Emphasis on Newly Described Entities
Intraductal salivary gland tumors represent a distinct and intriguing subset of salivary gland neoplasms, characterized by...
Novel Case of a Molecularly Confirmed Low-Grade Fibromyxoid Sarcoma of the Floor of the Mouth and Literature Review
Novel Case of a Molecularly Confirmed Low-Grade Fibromyxoid Sarcoma of the Floor of the Mouth and Literature Review
Low-grade fibromyxoid sarcoma (LGFMS) is a deceptively bland spindle cell neoplasm with malignant potential, most commonly...
Circulating Tumor HPV DNA Kinetics for Squamous Cell Carcinoma of the Lacrimal Sac Treated with Chemoradiotherapy
Circulating Tumor HPV DNA Kinetics for Squamous Cell Carcinoma of the Lacrimal Sac Treated with Chemoradiotherapy
Lacrimal sac squamous cell carcinoma (LSSCC) is the most common tumor of the rare disease subsite of the nasolacrimal syst...
Intraosseous Atypical Verrucopapillary Epithelial Proliferation with Verrucous Carcinoma Features Evolving from a Keratinizing Odontogenic Cyst: Report of an Uncommon Variant and Review of the Literature
Intraosseous Atypical Verrucopapillary Epithelial Proliferation with Verrucous Carcinoma Features Evolving from a Keratinizing Odontogenic Cyst: Report of an Uncommon Variant and Review of the Literature
Developmental odontogenic cysts (DOCs) of the jawbones with overt luminal keratinization, i.e., odontogenic keratocyst (OK...
Mechanistic Insights into Calcium Oxalate Crystals in Aspergillosis of the Maxillary Sinus
Mechanistic Insights into Calcium Oxalate Crystals in Aspergillosis of the Maxillary Sinus
Aspergillus species can induce calcium oxalate crystal deposition, serving as an important diagnostic marker when typical ...
Mucoacinar Carcinoma of the Parotid Gland
Mucoacinar Carcinoma of the Parotid Gland
Mucoacinar carcinoma is an exceedingly rare subtype of mucoepidermoid carcinoma with serous acinar differentiation. We pre...
Artificial Intelligence Basics for Head and Neck Pathologists: A Simple Guide
Artificial Intelligence Basics for Head and Neck Pathologists: A Simple Guide
Artificial intelligence (AI) is reshaping pathology practice by assisting pathologists in analyzing and interpreting compl...
Oral Glycogenic Acanthosis: A Clinicopathological Analysis of 13 Cases and Narrative Literature Review
Oral Glycogenic Acanthosis: A Clinicopathological Analysis of 13 Cases and Narrative Literature Review
Glycogenic acanthosis (GA) is a benign epithelial lesion characterized by intracellular glycogen accumulation, most seen i...
Impact of Transfer Learning on Convolutional Neural Networks for Odontogenic Tumor Diagnosis
Impact of Transfer Learning on Convolutional Neural Networks for Odontogenic Tumor Diagnosis
This study aimed to evaluate the coherence between data heterogeneity and model complexity by comparing seven convolutiona...
Epidemiology and Clinicopathologic Features with Prognostic Implications of Conventional Ameloblastoma: A 22-Year Retrospective Study
Epidemiology and Clinicopathologic Features with Prognostic Implications of Conventional Ameloblastoma: A 22-Year Retrospective Study
Ameloblastoma is the most common odontogenic neoplasm of the jaws, characterized by locally aggressive behavior and high r...
Spatial transcriptomics and artificial intelligence: a scoping review of emerging applications in head and neck pathology
Spatial transcriptomics and artificial intelligence: a scoping review of emerging applications in head and neck pathology
Single cell spatially resolved transcriptomics (ST) has revolutionized molecular profiling by providing the visualization ...
Laryngeal ALK Positive Histiocytosis: Potential Mimic of Inflammatory Myofibroblastic Tumor—Case Report and Literature Review
Laryngeal ALK Positive Histiocytosis: Potential Mimic of Inflammatory Myofibroblastic Tumor—Case Report and Literature Review
ALK positive histiocytosis (APH) is a rare histiocytic neoplasm defined by an ALK fusion and generally characterized by a ...
Sinonasal Nonkeratinizing Squamous Cell Carcinoma with Synchronous Presence of HPV-High Risk and Fusion
Sinonasal Nonkeratinizing Squamous Cell Carcinoma with Synchronous Presence of HPV-High Risk and Fusion
An increased understanding of molecular alterations over the last decade has also impacted the landscape of sinonasal squa...
Xenogeneic Collagen-Based Dural Substitute, A Stranger in Sinonasal Pathology
Xenogeneic Collagen-Based Dural Substitute, A Stranger in Sinonasal Pathology
Sinonasal mesenchymal neoplasms are challenging to classify due to their rarity. Xenogeneic collagen-based dural substitut...
Molecularly Variant Synovial Sarcoma of the Lower Lip: :: Fusion as a Diagnostic Pitfall in the Head and Neck
Molecularly Variant Synovial Sarcoma of the Lower Lip: :: Fusion as a Diagnostic Pitfall in the Head and Neck
Synovial sarcoma is a malignant mesenchymal neoplasm typically characterized by SS18::SSX gene fusions. Although most comm...
Proceedings of the 2026 North American Society of Head and Neck Pathology Companion Meeting, San Antonio, TX, March 22, 2026: It’s a Trap! Pitfalls in Thyroid Pathology: Mets or Not Mets?
Proceedings of the 2026 North American Society of Head and Neck Pathology Companion Meeting, San Antonio, TX, March 22, 2026: It’s a Trap! Pitfalls in Thyroid Pathology: Mets or Not Mets?
Similar to other head and neck organs, thyroid pathology encompasses a broad spectrum of diagnostic entities. The signific...
Integrated Clinical, Histopathological, and Inflammatory Parameters for Predicting Malignant Transformation in High-Risk Oral Potentially Malignant Disorders: A Prospective Study
Integrated Clinical, Histopathological, and Inflammatory Parameters for Predicting Malignant Transformation in High-Risk Oral Potentially Malignant Disorders: A Prospective Study
Oral epithelial dysplasia (OED) is a recognised precursor of oral squamous cell carcinoma (OSCC). Previous studies have id...
International Consensus Guidelines for Diagnostic Criteria and Checklist for Future Studies for Minimally Invasive Carcinoma ex Pleomorphic Adenoma: An HN CLEAR Initiative
International Consensus Guidelines for Diagnostic Criteria and Checklist for Future Studies for Minimally Invasive Carcinoma ex Pleomorphic Adenoma: An HN CLEAR Initiative
A variety of factors, including the extent of invasion, determine the clinical outcome in patients with carcinoma ex pleom...
Lipomatous Metaplasia in a Warthin Tumor: A Rare Histopathological Finding
Lipomatous Metaplasia in a Warthin Tumor: A Rare Histopathological Finding
We present a case of Warthin tumor (WT) exhibiting lipomatous metaplasia. This rare histopathological feature can mimic li...
Revision of an Early History of Calcifying Epithelial Odontogenic Tumor: Herkert’s Original Description (1914)
Revision of an Early History of Calcifying Epithelial Odontogenic Tumor: Herkert’s Original Description (1914)
Polti LF, Gorrino-Baquero RB, Villegas KM, Amaya-Londoňo N, Paparella ML (2025) Calcifying epithelial odontogenic tumour (...
Human Dirofilariasis– An Underrecognized Zoonosis
Human Dirofilariasis– An Underrecognized Zoonosis
Dirofilariasis is a rare zoonotic disease caused by the filarial nematode of the genus Dirofilaria. It is an uncommon zoon...
Metastatic SMARCA4-Deficient Undifferentiated Carcinoma of the Oral Cavity: A Case Report and Review of Literature
Metastatic SMARCA4-Deficient Undifferentiated Carcinoma of the Oral Cavity: A Case Report and Review of Literature
SMARCA4-deficient high-grade malignancies are increasingly recognized across various anatomic sites, namely the genitourin...
Metastatic Intraparotid Balloon Cell Melanoma: A Diagnostic Challenge
Metastatic Intraparotid Balloon Cell Melanoma: A Diagnostic Challenge
BCM is an uncommon cytomorphologic variant with the potential to mimic unrelated neoplastic conditions, especially in the ...
Reticular and Myxoid Variant of EBV-positive Nasopharyngeal Carcinoma Mimicking Salivary Gland Tumors: A Case Series
Reticular and Myxoid Variant of EBV-positive Nasopharyngeal Carcinoma Mimicking Salivary Gland Tumors: A Case Series
This study aims to characterize the rare morphological variant of nasopharyngeal carcinoma known as reticular and myxoid n...
Unusual Locations of Extra-Glossal Ectomesenchymal Chondromyxoid Tumors with Gene Fusions: A Report of Two Cases
Unusual Locations of Extra-Glossal Ectomesenchymal Chondromyxoid Tumors with Gene Fusions: A Report of Two Cases
Ectomesenchymal chondromyxoid tumor (EMCMT) is a rare benign tumor of the oral cavity that nearly always occurs in the ant...
Palisading Adenocarcinoma: Several New Inherited Cases in Six Patients of a Familial Cohort
Palisading Adenocarcinoma: Several New Inherited Cases in Six Patients of a Familial Cohort
The past two decades have seen the introduction of several new variants of established salivary gland tumors, along with o...
A Novel Odontogenic Carcinoma with CDK4/MDM2 Co-Amplification: Expanding the Phenotypic Spectrum of Malignant Odontogenic Entities
A Novel Odontogenic Carcinoma with CDK4/MDM2 Co-Amplification: Expanding the Phenotypic Spectrum of Malignant Odontogenic Entities
CDK4/MDM2 co-amplification, a molecular aberration predominantly observed in sarcomas, has not been previously reported in...
Refinement of Hyams Grading Criteria for Olfactory Neuroblastoma in an Endoscopic Sinus Surgery Predominant Cohort with Extended Follow-up: Worth the Effort?
Refinement of Hyams Grading Criteria for Olfactory Neuroblastoma in an Endoscopic Sinus Surgery Predominant Cohort with Extended Follow-up: Worth the Effort?
Hyams grading is considered prognostic in olfactory neuroblastoma (ONB), but grading criteria are subjective and predate m...
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