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The orphan receptor GPRC5B promotes macrophage infiltration and an inflammatory plaque phenotype in atherosclerosis
Atherosclerosis is a major pathophysiological feature of cardiovascular disease and remains a leading cause of morbidity a...
Variable regional histomorphology of the ascending aorta: Implications for disease classification
Surgical pathologists frequently examine ascending aortic specimens in the context of aneurysm or dissection. In such case...
Thoracic aortic diseases: Identification of diagnostic biomarkers using proteomic analysis
Introduction: Thoracic aortic aneurysms frequently go undetected until serious complications like acute dissections or rup...
Quantified calcification in rat aortic valves isolated with the sinus of Valsalva coordinates with calciprotein particles formation
Cardiovascular calcification is a serious complication in patients with chronic kidney disease (CKD) [1]. In patients with...
Aortic wall lamellar structure in phylogeny and in humans: insights from bicuspid and tricuspid aortic valve morphology
Volume 80, January–February 2026, 107789Author links open overlay panel, , , , , , , Highlights•The number of elastic lame...
Circ_0005372 targets the miR-153-3p/ITGB3 axis to stimulate the PI3K/AKT signaling pathway to facilitate the occurrence and development of congenital heart disease and pulmonary arterial hypertension in children
Congenital heart disease (CHD) arises due to malformations in the cardiovascular system that resulted from abnormal develo...
Pathological capillary analysis of ischemia with non-obstructive coronary arteries in a Fabry disease patient receiving enzyme replacement therapy
Fabry disease is a lysosomal disorder caused by a deficiency or lack of α-galactosidase A (GLA). This leads to the histopa...
Characterization of the clinical, histopathologic, and immunohistochemical features of large papillary fibroelastomas and their S100-expressing spindle cell component and its potential relationship to cardiac valvular interstitial cells
Papillary fibroelastomas (PFEs) are benign endocardial tumors that now represent the most commonly diagnosed primary cardi...
Comparative investigation of Cx3cr1-Expressing Cardiac Macrophages in Atrioventricular Nodes of Wild-Type and Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model
Congenital forms of arrhythmia could arise from mutations in genes encoding ion channels and proteins involved in their re...
Regional and temporal changes in early structural remodeling following myocardial infarction via semi-automatic image analysis
Each year over 800,000 people in the United States have a heart attack or myocardial infarction (MI) which involves occlus...
Spatial transcriptomics in the human left atrial appendage and pulmonary vein sleeve
Volume 81, March–April 2026, 107802Author links open overlay panel, , , , , , , , , Highlights•Spatial transcriptomics ill...
Mapping cardiac innervation in the long QT syndrome type 1 transgenic mouse model using whole heart imaging
Arrhythmia is a prevalent form of cardiovascular disease that could lead to mortality [1]. Long QT syndrome (LQTS) is an i...
Meta-analysis of differential gene expression in idiopathic pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) encompasses a group of syndromes involving elevations in pulmonary artery pressures ...
Genetic mutations, pathology, and single-nucleus transcriptomic landscape in LVHT patients reveal differential progression to heart transplantation
Left ventricular hypertrabeculation/non-compaction (LVHT/LVNC) is a genetic cardiomyopathy characterized by an abnormal my...
Usefulness of electron microscopy in the diagnosis of heterozygous Fabry disease with left ventricular outflow tract obstruction masquerading as hypertrophic cardiomyopathy
Fabry disease, characterized by α-galactosidase A (GLA) deficiency, causes left ventricular hypertrophy (LVH) often mimick...
Transforming growth factor-beta (TGF-β) in the pathogenesis of hereditary thoracic aneurysm disorders
The transforming growth factor-beta (TGF-β) signaling pathway regulates biological processes critical to embryonic develop...
Descriptive study of the clinical and myocardial status of a population with anatomopathological aortic valve amyloidosis
Volume 81, March–April 2026, 107807Author links open overlay panel, , , , , , Section snippetsCRediT authorship contributi...
Corrigendum to “The mitochondrial uncoupler 2,4-dinitrophenol modulates inflammatory and oxidative responses in Trypanosoma cruzi -induced acute myocarditis in mice” [Cardiovascular Pathology 72 (2024) 107653]
Volume 81, March–April 2026, 107806Author links open overlay panelJosé Edson Caetano-da-Silva a, Elda Gonçalves-Santos b, ...
Patent foramen ovale: A variant of normal or a true congenital heart disease?
Volume 76, May–June 2025, 107722Author links open overlay panel, , , , Highlights•Patent foramen ovale is a concealed cong...
Insights from autopsy-initiated pathological studies of the pathogenesis and clinical manifestations of atherosclerosis and ischemic heart disease: Part II. Ischemic heart disease
In the twentieth century, advances in clinical medicine and public health measures have led to a marked reduction in the d...
Insights from autopsy-initiated pathological studies of the pathogenesis and clinical manifestations of atherosclerosis and ischemic heart disease: Part I. Atherosclerosis
In the twentieth century, ischemic heart disease (IHD) due to coronary atherosclerosis, also known as coronary heart disea...
Seasonal variation of unexpected sudden cardiac death in northern Finland
Volume 76, May–June 2025, 107725Author links open overlay panel, , , , , , , , , Highlights•Consecutive unexpected sudden ...
Mitral Isthmus anatomy: Detailed examination and classification proposal
The mitral isthmus (MI) or also known as the left atrial isthmus is a part of the posteroinferior site of the lateral left...
Intimal sarcoma of the lower pulmonary vein diagnosed by Endobronchial Ultrasound-Guided Fine-Needle Aspiration (EBUS-FNA): A case report and comprehensive literature review
Volume 76, May–June 2025, 107717Author links open overlay panel, , , Highlights•A rare case of intimal sarcoma of the lowe...
The anti-atherosclerosis effect and molecular mechanism of AMPKα1 by polarizing monocytes to an M2 phenotype via cell-intrinsic lysosomal lipolysis
Atherosclerosis (AS) is an inflammatory disease characterized by the infiltration of immune cells into the arterial wall a...
Molecular Features and Cell Composition of Left-Dominant Arrhythmogenic Cardiomyopathy Reveals Key Pathways and Therapeutic Targets
Available online 16 May 2025, 107743Author links open overlay panel, , , , , , , , Highlights•Comprehensive single-nucleus...
Defining “Vulnerable” in coronary artery disease: predisposing factors and preventive measures
The presence of specific high-risk atherosclerotic plaque characteristics, namely high PB, low MLA, TCFA, high lipid core ...
The impact of moderate and high intensity endurance exercise on acute murine coxsackievirus B3 myocarditis
Background and aimsMyocarditis is a group of inflammatory diseases of the myocardium, with viral infections being the lead...
The frequency of CD3+ lymphocytes in non-myocarditis endomyocardial biopsies
In 1984, the Dallas Criteria were created, which established the first international framework for diagnosing lymphocytic ...
Temporal and demographic disparities in mortality trends for heart failure and COPD-associated heart failure in U.S. Adults: A 1999–2020 analysis of CDC WONDER data
BackgroundHeart failure (HF) carries varying mortality based on demographic distribution. Moreover, the interaction of HF ...
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