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Wearable transcutaneous electrical nerve stimulation (actiTENS®) is effective and safe for the treatment of knee osteoarthritis pain: a randomized controlled trial versus weak opioids
Wearable transcutaneous electrical nerve stimulation (actiTENS®) is effective and safe for the treatment of knee osteoarthritis pain: a randomized controlled trial versus weak opioids
Introduction:Despite their poor tolerance, especially in the elderly, weak opioids (WO) remain commonly prescribed for pat...
Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)
Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)
Background:Involvement of the axial skeleton (sacroiliac joints and spine) is a relatively frequent manifestation associat...
Consensus evidence-based recommendations for treat-to-target management of immunoglobulin A vasculitis
Consensus evidence-based recommendations for treat-to-target management of immunoglobulin A vasculitis
IgA vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, is the most common cause of systemic vasculitis in chil...
Role of antifibrotics in the management of idiopathic inflammatory myopathy associated interstitial lung disease
Role of antifibrotics in the management of idiopathic inflammatory myopathy associated interstitial lung disease
The antifibrotic therapies nintedanib and pirfenidone were first approved by the United States for the treatment of idiopa...
Psychological profiles in adults with knee OA-related pain: a replication study
Psychological profiles in adults with knee OA-related pain: a replication study
Introduction:Psychological factors have been associated with knee osteoarthritis pain severity and treatment outcomes, yet...
Bronchoalveolar lavage and lung biopsy in connective tissue diseases, to do or not to do?
Bronchoalveolar lavage and lung biopsy in connective tissue diseases, to do or not to do?
Bronchoalveolar lavage and lung biopsy (LBx) are helpful in patients with connective tissue diseases (CTD) and interstitia...
Radiosynovectomy in routine care: an old tool with modern applications
Radiosynovectomy in routine care: an old tool with modern applications
Objectives:Radiosynovectomy can be an effective treatment for difficult-to-treat monoarthritis resistant to systemic and l...
Update on the therapy of adult-onset Still’s disease with a focus on IL-1-inhibition: a systematic review
Update on the therapy of adult-onset Still’s disease with a focus on IL-1-inhibition: a systematic review
Introduction:The past decade has seen increasingly rapid advances in understanding the pathogenic nature of adult-onset St...
Comparison of long-term efficacy between biological agents following tumor necrosis factor inhibitor failure in patients with rheumatoid arthritis: a prospective cohort study
Comparison of long-term efficacy between biological agents following tumor necrosis factor inhibitor failure in patients with rheumatoid arthritis: a prospective cohort study
Background:Currently, there is contradictory evidence regarding the best strategy to follow after discontinuation of a fir...
Epidemiology and risk of invasive fungal infections in systemic lupus erythematosus: a nationwide population-based cohort study
Epidemiology and risk of invasive fungal infections in systemic lupus erythematosus: a nationwide population-based cohort study
Introduction:Infections are a leading cause of mortality in patients with systemic lupus erythematosus (SLE). Among variou...
Prevalence and risk factors of moderate to severe hepatic steatosis in patients with rheumatoid arthritis: an ultrasonography cross-sectional case–control study
Prevalence and risk factors of moderate to severe hepatic steatosis in patients with rheumatoid arthritis: an ultrasonography cross-sectional case–control study
Background:The independent association between hepatic steatosis and rheumatoid arthritis is poorly defined.Methods:The pr...
Response to Alvarez et al.
Response to Alvarez et al.
1. Alvarez, G, Zegarra-Parodi, R, Esteves, JE. Person-centered versus body-centered approaches in osteopathic care for chr...
Rapid improvement in spinal pain in patients with axial spondyloarthritis treated with secukinumab: primary results from a randomized controlled phase-IIIb trial
Rapid improvement in spinal pain in patients with axial spondyloarthritis treated with secukinumab: primary results from a randomized controlled phase-IIIb trial
Background:This study aimed to evaluate the efficacy and safety of secukinumab 150 mg compared with placebo in the managem...
Characterization of disease course and remission in early seropositive rheumatoid arthritis: results from the TACERA longitudinal cohort study
Characterization of disease course and remission in early seropositive rheumatoid arthritis: results from the TACERA longitudinal cohort study
Background:To characterise disease course and remission in a longitudinal observational study of newly diagnosed, initiall...
The role of upadacitinib in the treatment of moderate-to-severe active rheumatoid arthritis
The role of upadacitinib in the treatment of moderate-to-severe active rheumatoid arthritis
Despite recent promising developments in the treatment of rheumatoid arthritis (RA), a substantial proportion of patients ...
Diagnosis and management of lung involvement in systemic lupus erythematosus and Sjögren’s syndrome: a literature review
Diagnosis and management of lung involvement in systemic lupus erythematosus and Sjögren’s syndrome: a literature review
Lung involvement in systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) has extensively been outlined ...
Soluble biological markers in osteoarthritis
Soluble biological markers in osteoarthritis
In recent years, markers research has focused on the structural components of cartilage matrix. Specifically, a second gen...
Repurposing haloperidol for the treatment of rheumatoid arthritis: an integrative approach using data mining techniques
Repurposing haloperidol for the treatment of rheumatoid arthritis: an integrative approach using data mining techniques
Introduction:Treatment of rheumatoid arthritis (RA) has advanced with the introduction of biological disease-modifying ant...
Distribution of comorbidities in spondyloarthritis with regard to the phenotype and psoriasis: data from the ASAS-COMOSPA study
Distribution of comorbidities in spondyloarthritis with regard to the phenotype and psoriasis: data from the ASAS-COMOSPA study
Introduction:The aim of the study was to compare the prevalence of comorbidities between patients with axial and periphera...
Anakinra and canakinumab for patients with R92Q-associated autoinflammatory syndrome: a multicenter observational study from the AIDA Network
Anakinra and canakinumab for patients with R92Q-associated autoinflammatory syndrome: a multicenter observational study from the AIDA Network
Background:This study aims at describing the therapeutic outcome of patients carrying the R92Q variant in the TNFRSF1A gen...
Comparative effectiveness of treatment options for subacromial shoulder conditions: a systematic review and network meta-analysis
Comparative effectiveness of treatment options for subacromial shoulder conditions: a systematic review and network meta-analysis
Background:There are currently many treatment options for patients with subacromial shoulder conditions (SSCs). Clinical d...
Natural history and screening of interstitial lung disease in systemic autoimmune rheumatic disorders
Natural history and screening of interstitial lung disease in systemic autoimmune rheumatic disorders
Interstitial lung disease (ILD) is a relatively frequent manifestation of systemic autoimmune rheumatic disorders (SARDs),...
Secukinumab in axial spondyloarthritis: a narrative review of clinical evidence
Secukinumab in axial spondyloarthritis: a narrative review of clinical evidence
Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic disease characterized by inflammation and new bone for...
Corticosteroid injection treatment for dactylitis in psoriatic arthritis
Corticosteroid injection treatment for dactylitis in psoriatic arthritis
Dactylitis – a hallmark clinical feature of psoriatic arthritis (PsA) – that occurs in 30–50% of PsA patients, is a marker...
Factors associated with risk of major adverse cardiovascular events in patients with rheumatoid arthritis: a nationwide, population-based, case-control study
Factors associated with risk of major adverse cardiovascular events in patients with rheumatoid arthritis: a nationwide, population-based, case-control study
Objectives:To investigate factors associated with major adverse cardiovascular events (MACEs) in patients with rheumatoid ...
Autologous stem-cell transplantation in systemic sclerosis-associated interstitial lung disease: early action in selected patients rather than escalation therapy for all
Autologous stem-cell transplantation in systemic sclerosis-associated interstitial lung disease: early action in selected patients rather than escalation therapy for all
Systemic sclerosis (SSc) is a rare rheumatic disease characterised by inflammation, vasculopathy and fibrosis of skin and ...
Association of anti-thyroid antibodies with radiographic knee osteoarthritis and chondrocalcinosis: a NHANES III study
Association of anti-thyroid antibodies with radiographic knee osteoarthritis and chondrocalcinosis: a NHANES III study
Objectives:To examine the relationships between radiographic knee osteoarthritis (RKOA), symptomatic radiographic knee ost...
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