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Neuroprotective therapies for neonatal hypoxic-ischemic brain injury – a contemporary update
Neonatal encephalopathy of hypoxic-ischemic origin remains a leading cause of global neonatal mortality. Over the past dec...
Leveraging neonatal neuroimaging for neuroprognostication in presumed hypoxic-ischemic encephalopathy: A framework for clinicians
Brain magnetic resonance imaging (MRI) in neonates with presumed hypoxic-ischemic encephalopathy (HIE) offers a unique win...
Neonatal neuroimaging: from research to bedside practice
Neonatal neuroimaging is essential in research and clinical practice, offering important insights into brain development a...
The role of sleep in neonatal neurocritical care and the influence on long-term outcome
Prematurity, birth complications, and congenital brain abnormalities can lead to neurological conditions that require inte...
Remote neonatal neurocritical care: from the bedside to the cloud
Neonatal neurocritical care (NNCC) has emerged as a specialized discipline to address the unique neurological needs of cri...
Integrating climate vulnerability as a social determinant of health: Screening, counseling, and promoting resilience for pregnant people, neonates and families
Global warming is a predominantly human-caused phenomenon that is altering the planetary and atmospheric environment. Thes...
Who you gonna call? Understanding the shortages of the pediatric subspecialty workforce
Concerns regarding provision of specialized care of children have received increased attention due to recent and sustained...
Technical considerations and applications of point-of-care ultrasound in the NICU
Available online 5 December 2025, 152190Author links open overlay panel, , , , , , AbstractPoint-of-care ultrasound (POCUS...
Medical legal partnerships in the neonatal intensive care unit
Medical-legal partnerships (MLPs) are healthcare delivery models that involve a multi-disciplinary team including clinicia...
Prediction of preterm birth: past, present, and future approaches to an ongoing challenge
Preterm birth (PTB), defined as delivery between 20 0/7 weeks and 36 6/7 weeks of gestation, remains a major public health...
Landmark clinical trials on preterm birth prevention that have changed clinical practice
Spontaneous preterm birth remains a leading global cause of neonatal morbidity and mortality, with lasting health socioeco...
Delivering health insurance coverage for babies: A primer on Medicaid for perinatal care providers
Perinatal health outcomes directly relate to insurance coverage. The Medicaid program is the single largest health insurer...
Improving perinatal outcomes: A review of landmark trials that have changed obstetric practice
Over the past few decades, multiple landmark studies investigating interventions for perinatal benefit have determined bes...
Clinical trials in fetal surgery - changing care for complex pregnancies
Over the past few decades the field of fetal therapy has experienced several paradigm shifts. While initially targeted at ...
Mitigating threats, maximizing opportunities: Harnessing post-pandemic heath services to strengthen the safety net for perinatal patients
Available online 17 December 2025, 152198Author links open overlay panelHeather L. Brumberg, Shetal ShahShow moreAccess th...
The impact of preferred language on perinatal health
Preferring a language other than English (LOE) is associated with numerous disparities across healthcare. Despite the fede...
Trials that have changed maternal care
Landmark trials impact how we care for patients. These studies often have convincing data that lead to new or updated prac...
Perinatal mental health: Screening and impact on health outcomes
Mental illness affects up to 20 % of women of reproductive age. Maternal mental illness pre-pregnancy and/or during pregna...
Preeclampsia trials that changed practice
Eniola R. Ibirogba: Writing – original draft, Data curation, Conceptualization. Jennifer Grasch: Writing – review & ed...
Advancing evidence for maternal and fetal health: Clinical trials that changed practice
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Decision science in perinatal decision making
Volume 49, Issue 3, April 2025, 152064Author links open overlay panelAbstractPerinatologists and the families they support...
Non-invasive ventilation of preterm infants in the delivery room
The approach to respiratory support in preterm infants at birth has shifted from invasive to non-invasive techniques. The ...
Non-invasive respiratory support paired with minimally invasive surfactant therapy in preterm infants
Non-invasive ventilation (NIV) commenced soon after birth is highly effective in providing mechanical respiratory support ...
The ethical imperative to pursue neonatal health equity and justice
Racial and ethnic inequity are a well-recognized phenomenon in neonatal and infant care. Since the pioneering 1997 study b...
Ethics, maternal-fetal interventions, and the technological imperative
In medicine, the technological imperative presupposes the inevitable and essential adoption of technologies for the benefi...
The evolution of teratology: Historical perspectives and lessons learned
Teratology, the study of congenital anomalies caused by environmental, chemical, and biological factors, derives from the ...
When pregnancy termination fails: A tale of two teratogens: methotrexate and misoprostol – A narrative mini-review
Methotrexate, an anti-folate, and misoprostol, a prostaglandin E1-analog, are both used for disease treatment and preventi...
Teratogenic risks of treated and untreated maternal obesity
Overweight (BMI 25–29.9 kg/m2) and obesity (BMI ≥ 30 kg/m2) are estimated to affect 59% of adults worldwide1 and 73% of ad...
Thyroid disease as a teratogen
Thyroid disorders are common in pregnant patients and effective management is critical for maternal, fetal, and neonatal h...
Review of pharmacology of medications during pregnancy
Medication use during pregnancy is common with 9 in 10 women taking medication during pregnancy.1 In some cases, certain c...
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