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Resolvin D1 attenuates Ang II-induced hypertension in mice by inhibiting the proliferation, migration and phenotypic transformation of vascular smooth muscle cells by blocking the RhoA/mitogen-activated protein kinase pathway
Resolvin D1 attenuates Ang II-induced hypertension in mice by inhibiting the proliferation, migration and phenotypic transformation of vascular smooth muscle cells by blocking the RhoA/mitogen-activated protein kinase pathway
The proliferation, migration and phenotypic transformation of vascular smooth muscle cells contribut
Decreased toll-like receptor 4 and CD11b/CD18 expression on peripheral monocytes of hypertensive patients correlates with a lesser extent of endothelial damage: a preliminary study
Decreased toll-like receptor 4 and CD11b/CD18 expression on peripheral monocytes of hypertensive patients correlates with a lesser extent of endothelial damage: a preliminary study
Background: Low-grade chronic inflammation is recognized to contribute to the physiopathology of
Use trends of chlorthalidone and hydrochlorothiazide among United States adults with hypertension: National Health and Nutrition Examination Survey 2009–2018
Use trends of chlorthalidone and hydrochlorothiazide among United States adults with hypertension: National Health and Nutrition Examination Survey 2009–2018
Objectives: To estimate the national prevalence of chlorthalidone and hydrochlorothiazide use amo
Lactobacillus induced by irbesartan on spontaneously hypertensive rat contribute to its antihypertensive effect
Lactobacillus induced by irbesartan on spontaneously hypertensive rat contribute to its antihypertensive effect
Objective: Hypertension is linked to gut dysbiosis. Here, the impact of the angiotensin receptor
FOXO3 longevity genotype attenuates the impact of hypertension on cerebral microinfarct risk
FOXO3 longevity genotype attenuates the impact of hypertension on cerebral microinfarct risk
Objective: The G-allele of FOXO3 SNP rs2802292, which is associated with human resilience and lon
Hypoxia-inducible factor-prolyl hydroxylase inhibitor Roxadustat (FG-4592) reduces renal fibrosis in Dahl salt-sensitive rats
Hypoxia-inducible factor-prolyl hydroxylase inhibitor Roxadustat (FG-4592) reduces renal fibrosis in Dahl salt-sensitive rats
Objective: Although hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitors have been dev
Accumulation of advanced glycation end products in skin and increased vascular ageing in the general population: the Malmö Offspring Study
Accumulation of advanced glycation end products in skin and increased vascular ageing in the general population: the Malmö Offspring Study
Objectives: Advanced glycation end product (AGE) is an established risk marker for diabetic vascu
The association of time-updated ambulatory blood pressure and renal progression in hypertensive patients with chronic kidney disease: post hoc analysis of ACCURATE study
The association of time-updated ambulatory blood pressure and renal progression in hypertensive patients with chronic kidney disease: post hoc analysis of ACCURATE study
Objectives : This study aimed to evaluate the effect of time-updated ambulatory blood pressure on
Hypertension in the first blood pressure reading and the risk of cardiovascular disease mortality in the general population: findings from the prospective KORA study
Hypertension in the first blood pressure reading and the risk of cardiovascular disease mortality in the general population: findings from the prospective KORA study
Background: The risk of cardiovascular disease (CVD) mortality in individuals with an alerting re
Reversal of arterial stiffness in medically and surgically treated unilateral primary aldosteronism
Reversal of arterial stiffness in medically and surgically treated unilateral primary aldosteronism
Objective: Hyperaldosteronism has adverse effects on cardiovascular structure and function. Lapar
Rapid Gastric emptying in spontaneously hypertensive rats
Rapid Gastric emptying in spontaneously hypertensive rats
Objective: To assess the rate of gastric emptying in spontaneously hypertensive rats (SHR) and to
Early vascular damage in retinal microcirculation in arterial hypertension: the Czech post-MONICA study
Early vascular damage in retinal microcirculation in arterial hypertension: the Czech post-MONICA study
Retinal microcirculation reflects retinal perfusion abnormalities and retinal arterial structural ch
Application of deep neural survival networks to the development of risk prediction models for diabetes mellitus, hypertension, and dyslipidemia
Application of deep neural survival networks to the development of risk prediction models for diabetes mellitus, hypertension, and dyslipidemia
Objectives : Although numerous risk prediction models have been proposed, few such models have be
Mineralocorticoid receptor antagonist treatment in patients with renal insufficiency and the associated risk of hyperkalemia and death
Mineralocorticoid receptor antagonist treatment in patients with renal insufficiency and the associated risk of hyperkalemia and death
Objectives: Mineralocorticoid receptor antagonist (MRA) treatment is kidney protective but not re
Circ_0001861 facilitates trophoblast cell proliferation, migration, invasion and epithelial-mesenchymal transition via the miR-296-5p/forkhead box protein 1 pathway in preeclampsia
Circ_0001861 facilitates trophoblast cell proliferation, migration, invasion and epithelial-mesenchymal transition via the miR-296-5p/forkhead box protein 1 pathway in preeclampsia
Background: Preeclampsia (PE) is one of the leading causes of maternal mortality and placental tr
Prognostic value of home versus ambulatory blood pressure monitoring: a systematic review and meta-analysis of outcome studies
Prognostic value of home versus ambulatory blood pressure monitoring: a systematic review and meta-analysis of outcome studies
Objectives: Ambulatory (ABP) and self-home blood pressure (HBP) measurements are known to be supe
Reply on: Analyzing the effects of sex hormone-binding globulin levels and development of hypertension in middle-aged men and women
Reply on: Analyzing the effects of sex hormone-binding globulin levels and development of hypertension in middle-aged men and women
We are grateful for the opportunity to answer to the comment by Patel et al. on our article titled ‘Sex hormone-binding gl...
Mineralocorticoid receptor antagonist for chronic kidney disease, risk or benefit?
Mineralocorticoid receptor antagonist for chronic kidney disease, risk or benefit?
The renin-angiotensin-aldosterone system (RAAS) is an important regulator of cardiac, vascular, and renal physiology via t...
Resolvin D1 as a novel target in the management of hypertension
Resolvin D1 as a novel target in the management of hypertension
Hypertension afflicts more than 1.4 billion people worldwide and remains a leading global public health concern, especiall...
Analyzing the effects of sex hormone-binding globulin levels and development of hypertension in middle-aged men and women
Analyzing the effects of sex hormone-binding globulin levels and development of hypertension in middle-aged men and women
aDepartment of Medicine, Rowan University School of Osteopathic Medicine, Stratford, New Jersey bDepartment o...
Association of blood pressure and heart rate with carotid markers of vascular remodeling in the young: a case for early prevention
Association of blood pressure and heart rate with carotid markers of vascular remodeling in the young: a case for early prevention
Objective: The association of childhood blood pressure (BP) and heart rate (HR) with intermediate
Prevalence and correlates of frailty in older hypertensive outpatients according to different tools: the HYPER-FRAIL pilot study
Prevalence and correlates of frailty in older hypertensive outpatients according to different tools: the HYPER-FRAIL pilot study
Objectives: To date, few studies have investigated frailty in hypertensive individuals. This stud
Effects of adding exercise to usual care on blood pressure in patients with hypertension, type 2 diabetes, or cardiovascular disease: a systematic review with meta-analysis and trial sequential analysis
Effects of adding exercise to usual care on blood pressure in patients with hypertension, type 2 diabetes, or cardiovascular disease: a systematic review with meta-analysis and trial sequential analysis
Introduction: Exercise is the most recommended lifestyle intervention in managing hypertension, t
Comparison between visit-to-visit office and 24-h blood pressure variability in treated hypertensive patients
Comparison between visit-to-visit office and 24-h blood pressure variability in treated hypertensive patients
Objectives: In any treated hypertensive patient office blood pressure (BP) values may differ betw
Antihypertensive drug concentration measurement combined with personalized feedback in resistant hypertension: a randomized controlled trial
Antihypertensive drug concentration measurement combined with personalized feedback in resistant hypertension: a randomized controlled trial
Background: Adherence to antihypertensive drugs (AHDs) is crucial for controlling blood pressure
Inactivation of the paraventricular nucleus attenuates the cardiogenic sympathetic afferent reflex in the spontaneously hypertensive rat
Inactivation of the paraventricular nucleus attenuates the cardiogenic sympathetic afferent reflex in the spontaneously hypertensive rat
Background: Myocardial ischemia causes the release of bradykinin, which stimulates cardiac affere
Cardiovascular outcomes according to on-treatment systolic blood pressure in older hypertensive patients: a multicenter cohort using a common data model
Cardiovascular outcomes according to on-treatment systolic blood pressure in older hypertensive patients: a multicenter cohort using a common data model
Objective: In the growing population of older patients with hypertension, limited evidence suppor
A cost-analysis of managing secondary and apparent treatment-resistant hypertension in a specialist multidisciplinary hypertension clinic
A cost-analysis of managing secondary and apparent treatment-resistant hypertension in a specialist multidisciplinary hypertension clinic
Objectives: A knowledge gap exists around the costs and budget impact of specialist hypertension
A Life in Medicine
A Life in Medicine
...
Authors’ response to “Impact of hypertension treatment-time on cardiovascular outcomes: erroneous trial selection leading to suspect findings”
Authors’ response to “Impact of hypertension treatment-time on cardiovascular outcomes: erroneous trial selection leading to suspect findings”
aDepartment of Cardiology, West Virginia University, Morgantown, West Virginia, USA bFaculty of Medicine, The...
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