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Optimization of tablet processing as a reference material for microplastic detection methods
Optimization of tablet processing as a reference material for microplastic detection methods
Reference materials (RMs) are essential and highly demanded tools for the development and validation of methods for microp...
Tailoring isomeric transformations and surface adsorption dynamics of glycopeptides under thermal and photolytic stress
Tailoring isomeric transformations and surface adsorption dynamics of glycopeptides under thermal and photolytic stress
Dalbavancin, unlike other peptides administered through the IV route, is highly influenced by subtle environmental shifts....
Development of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolites
Development of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolites
The gut microbiota produces metabolites that are important for host physiology and have critical roles in the development ...
Analysis and fate of per- and polyfluoroalkyl substances (PFAS) in the global aquatic environment: perspectives and combined risks with microplastics
Analysis and fate of per- and polyfluoroalkyl substances (PFAS) in the global aquatic environment: perspectives and combined risks with microplastics
Per- and polyfluoroalkyl substances (PFAS) are synthetic, highly persistent environmental contaminants increasingly recogn...
Evaluating the chemical safety of bio-based and biodegradable food packaging materials through non-targeted LC-HRMS analysis and in vitro bioassays
Evaluating the chemical safety of bio-based and biodegradable food packaging materials through non-targeted LC-HRMS analysis and in vitro bioassays
Bio-based and/or biodegradable polymers like all food-contact materials shall not transfer their constituents to food in q...
Metabolomic fingerprint of (Polygonaceae) using suspect screening with LC-HRMS and untargeted approach with GC-HRMS
Metabolomic fingerprint of (Polygonaceae) using suspect screening with LC-HRMS and untargeted approach with GC-HRMS
Knotweed (Reynoutria japonica) is an invasive plant whose ecological dominance in its invasive range may partly rely on al...
Development and optimization of PFAS extraction in soil’s headspace followed by multidimensional gas chromatography and mass spectrometry
Development and optimization of PFAS extraction in soil’s headspace followed by multidimensional gas chromatography and mass spectrometry
Per- and polyfluoroalkyl substances (PFAS) are a large class of synthetic “forever chemicals” due to their exc...
Electrochemical aptasensing of HER2 breast cancer biomarker using a Ni nanofoam/Ag–Au ternary nanocomposite
Electrochemical aptasensing of HER2 breast cancer biomarker using a Ni nanofoam/Ag–Au ternary nanocomposite
Human epidermal growth factor receptor 2 (HER2) is a key biomarker associated with breast cancer, and its reliable detecti...
Research advances in capillary electrophoresis coating technology for protein analysis
Research advances in capillary electrophoresis coating technology for protein analysis
Capillary electrophoresis (CE) is primarily a technique for separating and analyzing samples based on their differing phys...
IoT-integrated and portable real-time LAMP platform with hydroxy naphthol blue (HNB) for universal, low-cost pathogen detection in resource-limited settings
IoT-integrated and portable real-time LAMP platform with hydroxy naphthol blue (HNB) for universal, low-cost pathogen detection in resource-limited settings
The timely and cost-effective detection of infectious pathogens is critical for their prevention and control. In this stud...
Compensating thickness effects in micro X-ray fluorescence spectroscopy using integrated optical microscopy for thickness determination of soft matter block copolymer membranes
Compensating thickness effects in micro X-ray fluorescence spectroscopy using integrated optical microscopy for thickness determination of soft matter block copolymer membranes
A non-invasive method using the integrated optical microscope of a laboratory-based 2-dimensional micro X-ray fluorescence...
The benefits of multi-D LC × LC compared to LC × LC for the analysis of European herbal remedies
The benefits of multi-D LC × LC compared to LC × LC for the analysis of European herbal remedies
Due to the demand in alternative medicine to treat various diseases, medicinal plants as ancient remedies gained more rece...
Comparative evaluation of immunoaffinity and antibody-free isotope dilution mass spectrometry approaches for plasma ProGRP quantification
Comparative evaluation of immunoaffinity and antibody-free isotope dilution mass spectrometry approaches for plasma ProGRP quantification
Isotope dilution mass spectrometry (IDMS) is a critical technique for the quantification of protein biomarkers in complex ...
Quality evaluation of metabolite annotation based on comprehensive simulation of MS/MS data from high-resolution mass spectrometry (HRMS) and similarity scoring
Quality evaluation of metabolite annotation based on comprehensive simulation of MS/MS data from high-resolution mass spectrometry (HRMS) and similarity scoring
Metabolite annotation is a critical step in discovery metabolomics, but remains a significant challenge. In this study, th...
Combination of hydrophilic interaction liquid chromatography and top-down mass spectrometry for characterisation of adeno-associated virus capsid proteins
Combination of hydrophilic interaction liquid chromatography and top-down mass spectrometry for characterisation of adeno-associated virus capsid proteins
Adeno-associated virus (AAV) viral vector-based gene therapy is advancing rapidly, offering potential treatments for rare ...
Quality assurance and quality control for human biomonitoring data—focus on matrix reference materials
Quality assurance and quality control for human biomonitoring data—focus on matrix reference materials
Human biomonitoring (HBM) is an essential tool for making evidence-based policy decisions upon assessment of human exposur...
Testing of a novel automated point-of-care analyzer for blood ammonium monitoring in a clinical setting
Testing of a novel automated point-of-care analyzer for blood ammonium monitoring in a clinical setting
Certain diseases are marked by elevated ammonium levels in the blood, a condition known as hyperammonemia. Prompt detectio...
Mass spectrometry analysis of PM in poultry farms and the cytotoxicity and metabolism perturbation of BEAS-2B cells
Mass spectrometry analysis of PM in poultry farms and the cytotoxicity and metabolism perturbation of BEAS-2B cells
To evaluate the potential risks posed by farm-derived fine particulate matter (PM2.5), we conducted a comprehensive analys...
Unraveling the molecular dynamics of wound healing: integrating spatially resolved lipidomics and temporally resolved proteomics
Unraveling the molecular dynamics of wound healing: integrating spatially resolved lipidomics and temporally resolved proteomics
Understanding the spatial–temporal molecular dynamics of wound healing is crucial for devising effective treatments....
Functionalized magnetic covalent organic frameworks with refining tunable cores for highly selective adsorption of immunosuppressive drugs
Functionalized magnetic covalent organic frameworks with refining tunable cores for highly selective adsorption of immunosuppressive drugs
Immunosuppressant drugs (ISDs) are widely used in the treatment of organ rejection following human transplantation and in ...
PTR-MS analysis of fungal VOCs for early detection of oak wilt
PTR-MS analysis of fungal VOCs for early detection of oak wilt
Traditional methods for diagnosing bacterial or fungal infections, such as cell culture, are comprehensive but time-consum...
Efficient and sustainable recovery of bioactive compounds from cashew nut testa shell ( L.) using pressurized liquid extraction
Efficient and sustainable recovery of bioactive compounds from cashew nut testa shell ( L.) using pressurized liquid extraction
Cashew nut processing generates large quantities of byproducts daily, such as cashew nut testa shell (CNTS), which is disc...
Structural and functional optimization of COF-coated stirring bars for environmental monitoring and biological sample analysis
Structural and functional optimization of COF-coated stirring bars for environmental monitoring and biological sample analysis
In this study, a series of covalent organic framework (COF)-coated stirring bars—COF-a, COF-b, and COF-c—were ...
UHPLC-QTOF-MS-based metabolomics joint high-throughput RNA sequencing transcriptomics approach for the analysis of fecal and liver biological samples and application in a case study for the mechanism of Qing-Kai-Ling oral liquid in treating MASLD
UHPLC-QTOF-MS-based metabolomics joint high-throughput RNA sequencing transcriptomics approach for the analysis of fecal and liver biological samples and application in a case study for the mechanism of Qing-Kai-Ling oral liquid in treating MASLD
Qing-Kai-Ling (QKL) oral liquid has been increasingly used in metabolic dysfunction-associated steatotic liver disease (MA...
A homogeneous immunoassay technology based on liposomes and the complement system enables one-step, no-wash, rapid diagnostics directly in serum
A homogeneous immunoassay technology based on liposomes and the complement system enables one-step, no-wash, rapid diagnostics directly in serum
Liposomes are a well-established carrier and controlled release system in medicine and bioanalysis. Their biomimetic capab...
pH-tuned reversible self-assembly of Janus particles for enhanced Raman imaging and sensing
pH-tuned reversible self-assembly of Janus particles for enhanced Raman imaging and sensing
The controlled self-assembly of Janus particles via pH modulation offers an effective strategy for optimizing surface-enha...
Development and analysis of 49 perfluoroalkyl and polyfluoroalkyl substances (PFASs) in contact lenses using liquid chromatography-tandem mass spectrometry (LC–MS/MS)
Development and analysis of 49 perfluoroalkyl and polyfluoroalkyl substances (PFASs) in contact lenses using liquid chromatography-tandem mass spectrometry (LC–MS/MS)
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) possess water-repellent, oil-repellent, and heat-resistant propertie...
Evaluating inkjet dispenser/liquid vortex capture-mass spectrometry for single-cell metabolomics in Hep G2 steatosis caused by tamoxifen
Evaluating inkjet dispenser/liquid vortex capture-mass spectrometry for single-cell metabolomics in Hep G2 steatosis caused by tamoxifen
Single-cell mass spectrometry (MS) is advancing our understanding of metabolic pathways in heterogeneous cell populations;...
Dispersive solid-phase extraction as sample pretreatment for determination of chemotherapeutic agents revumenib and venetoclax by HPLC-DAD
Dispersive solid-phase extraction as sample pretreatment for determination of chemotherapeutic agents revumenib and venetoclax by HPLC-DAD
The first nanotechnology-based innovative analytical strategy by means of dispersive solid-phase extraction (DSPE) as a ne...
Comprehensive and high-coverage glycerophospholipidomic analysis based on iterative quadrupole time-of-flight mass spectrometry and its application in cerebral ischemia–reperfusion injury
Comprehensive and high-coverage glycerophospholipidomic analysis based on iterative quadrupole time-of-flight mass spectrometry and its application in cerebral ischemia–reperfusion injury
Glycerophospholipids play important roles in iron-induced lipid peroxidation during cerebral ischemia–reperfusion, m...
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