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Structuring complexity by mapping the possible in microbial ecosystems
Microbial ecosystems consist of many interacting components that integrate through stochastic and highly dynamic processes...
Applicability of synthetic communities of the infant gut microbiota to understand microbial dynamics in an interchanging glycan landscape
Researchers are exploring synthetic communities to better understand infant gut microbiota interactions. These reduced-div...
The cycad coralloid root: is there evidence for plant-microbe coevolution?
Cycads are survivors, ancient plants originating in the Carboniferous. We hypothesize that cycad resilience and recent div...
Transient microbial architects: tracing the legacy effects of ephemeral taxa during plant microbiome assembly
Plant microbiota assembly is a dynamic process shaped by a succession of microbial dispersal events, interactions, and env...
The role of mobile genetic elements in adaptation of the microbiota to the dynamic human gut ecosystem
The human intestinal microbiota plays essential roles in our health [1]. Extensive gene exchange occurs between the differ...
Taming wild replicons: evolution and domestication of large extrachromosomal replicons
Bacterial genomes often contain extrachromosomal replicons (ERs), ranging from small, mobile plasmids to large, stably inh...
The cell envelope of diderm bacteria: a unified scaffold, not a stack of layers
The cell envelope of diderm (Gram-negative) bacteria is a defining structural and functional feature, ensuring mechanical ...
Decoding the epigenetic blueprint behind Toxoplasma (pre)sexual commitment and chronic persistence
Toxoplasma gondii, a widespread apicomplexan parasite, navigates a complex life cycle in which it switches back and forth ...
Why transport matters: an update on carrier proteins in Apicomplexan parasites
The movement of molecules across the membranous barriers of a cell is fundamental to cellular homeostasis in every living ...
Crosstalk between malaria and host proteome during the intraerythrocytic developmental cycle
Like all pathogenic infectious agents, Plasmodium falciparum, the deadly malaria parasite, modulates its host environment ...
Physiology of atmospheric methane-oxidizing bacteria
The biological sink for atmospheric methane consists of atmospheric methane-oxidizing bacteria (atmMOB) that persistently ...
Trace gas oxidation as a novel microbial dispersal trait
Dispersal is a fundamental ecological process that enables colonization of new environments and controls community diversi...
New frontiers in short-chain alkyl-coenzyme M reductases
The planetary short-chain alkanes budget is impacted by methanogenic and alkanotrophic archaea in anaerobic environments. ...
Diversity and evolution of alphaproteobacterial dimorphism
Many bacteria have complex pleomorphic lifecycles — a feature particularly widespread across the class Alphaproteobacteria...
The complex developmental mechanisms of nucleus-forming jumbo phages
Bacteria have myriad mechanisms to resist the infections of predatory mobile genetic elements such as bacteriophages 1, 2,...
Microbial biomolecular condensates: from conserved principles to synthetic biology opportunities
Biomolecular condensates are membraneless compartments that organize cellular activities by selectively concentrating mole...
Subcellular organization of the archaeal cell
Unlike eukaryotes, archaea and bacteria are often considered devoid of intracellular vesicles and other compartments. Howe...
Editorial overview: Antibiotic discovery: Feeding the pipeline or finding new pipes?
Joshua Blodgett earned his PhD at the University of Illinois Urbana-Champaign, working on bacterial phosphonate antibiotic...
Host immunometabolic regulation through viral sensing pathways
Viruses are obligatory intracellular pathogens that depend on cellular machinery for replication and dissemination [1]. Si...
Current perspectives of host-pathogen dynamics in coccidioidomycosis
Valley fever is an invasive fungal infection caused when immunologically naïve individuals are exposed to arthroconidia of...
Targeted isolation of piperazate-containing molecules: bioinformatics and spectroscopy
Piperazic acid (Piz) is an intriguing hydrazine-containing amino acid found in a diverse variety of natural products, the ...
Protein families secreted by nematodes to modulate host immunity
Parasitic nematodes release a wide variety of immunomodulatory proteins, which allow them to escape the host’s immune-medi...
Induced pluripotent stem cell–based tissue models to study malaria: a new player in the research game
Most in vitro studies on parasite development and pathogenesis in the human host have been conducted using traditional pri...
Can a microbial community become an evolutionary individual?
Microbial communities provide crucial services for human well-being, driving an interest in designing and controlling them...
How pathogens drive adipose tissue loss in the host
Weight loss is a hallmark of many infections, including those caused by bacteria, fungi and parasites. This loss is often ...
Immune evasion runs in the family: two surface protein families of Plasmodium falciparum–infected erythrocytes
Two protein families are found on the surfaces of erythrocytes infected with Plasmodium falciparum, a causative agent of d...
The role of microbial succinate in the pathophysiology of inflammatory bowel disease: mechanisms and therapeutic potential
Inflammatory bowel disease (IBD) is a chronic, immune-mediated condition characterized by inflammation of the gastrointest...
Pathogen adaptation to lung metabolites
Upon invading mucosal tissues such as the lung, opportunistic pathogens must rapidly adapt to locally available carbon sou...
Specialized biopolymers: versatile tools for microbial resilience
Specialized biopolymers: versatile tools for microbial resilience
Biopolymers are a chemically diverse group of high-molecular-weight molecules composed of repeating building blocks, such ...
Multilayered regulation of amino acid metabolism in Escherichia coli
Multilayered regulation of amino acid metabolism in Escherichia coli
Escherichia coli primarily constitutes 0.1–5% of the mammalian gut microbiome and can also be found in the gut of birds, r...
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