SCI Abstract

search
+
Morphological regulation of filamentous fungi improves industrial production
Filamentous fungi are widely distributed in nature, capable of producing organic acids, enzymes, and a variety of natural ...
Spatial transcriptomics: integrating platforms and computational approaches for clinical insights
Traditional transcriptomics studies rely on the average expression across all cells, making it challenging to gain insight...
Enzyme symphony in bio-inspired multi-enzyme cascades for enhanced biosynthesis
Driven by multiple waves of biocatalysis, rapid advancements in protein engineering and bioinformatics have enabled the pr...
Integrating multi-omics and artificial intelligence fuels advanced target identification and drug discovery
Drug discovery is a multifaceted process that encompasses several critical stages, including target identification, compou...
Metabolic engineering strategies for enhanced microbial synthesis of lacto-N-neotetraose: a key acetylated human milk oligosaccharide
HMOs, a family of unconjugated glycans unique to human breast milk, rank as the third most prevalent solid component follo...
Membranes: The only chance for the mRNA tortoise to win, economically
The RNA revolution, advancing beyond traditional vaccines to new therapeutic modalities and constructs such as self-amplif...
Spatial engineering for biocatalytic cascade control through biomolecular compartmentalization
Natural living systems leverage compartmentalization as an evolutionary blueprint to orchestrate intricate biological proc...
The Midas touch: Recombinant antibodies transforming diagnostic platforms
In 1985, George Smith introduced phage display, a groundbreaking technique for presenting peptides fused to the bacterioph...
Application of CRISPR/Cas9 gene editing system in microalgal metabolic engineering and synthetic strategies of functional food ingredients
Microalgae are rich in biodiversity, with approximately 50,000 species discovered to date. They play a crucial role in nat...
Methane conversion into methanol by biotechnological processes: Challenges and perspectives
Methane is one of the most prominent greenhouse gases contributing to global warming. It is also a valuable source of ener...
A review on squalene production by engineered yeasts: Current advances and perspectives
Squalene, as a natural triterpenoid with a range of biological activities (Dessì et al., 2002), was first discovered in th...
Recent advances in microbial electron transfer-driven bio-reductive immobilization of heavy metals: Mechanisms, enhancement strategies, and perspectives
Heavy metals, particularly toxic elements like chromium, uranium, and selenium, pose persistent risks to ecosystems and hu...
Vanadium-dependent haloperoxidases: Recent advances and perspectives
Organohalogen compounds are essential in modern chemistry, serving as key structural motifs in pharmaceuticals, agrochemic...
Sensing for early-stage plant disease: From pathogenesis to sensor design
The expanding global population and intensified land use are placing agroforestry systems under growing strain (Blaser et ...
Controlling gene expression using AI designed Cis-regulatory elements
Synthetic biology aims to reprogram organisms by designing genetic circuits, in which transcriptional regulatory elements ...
Immobilization/incorporation methods of bacteriophages into polymeric films: Technological challenges & perspectives
Bacteriophage(phage)-based interventions have been considered for environmental and biomedical applications as well as dur...
Computational methods for spatial multi-omics integration
In multicellular systems, spatial organization is not only the external form that maintains cellular order but also a fund...
Biosynthesis of functional carbohydrates from glycolytic node precursors glucose-6-phosphate and fructose-6-phosphate: Advances and prospects
Biomanufacturing, an important and novel development model aimed at solving climate, energy, and food crises, has the adva...
Construction and applications of methanol bio-converting cell factories
Microbial cell factories have been constructed via synthetic biology to convert renewable feedstocks into high-value chemi...
Xylanases targeting unusual glycosidic bonds: Unlocking prebiotic xylooligosaccharides from macroalgae
The growing interest in functional foods and prebiotics has encouraged the search for novel bioactive ingredients. Macroal...
From formate oxidation to CO₂ reduction: The role of formate dehydrogenase in sustainable carbon utilization
The accelerating impacts of global climate change and the intensifying degradation of the environment have underscored the...
AI-driven de novo enzyme design: Strategies, applications, and future prospects
Enzyme design is a transformative approach for addressing a wide array of scientific, industrial, and medical challenges b...
Revolutionizing agroindustry: Towards the industrial application of antimicrobial peptides against pathogens and pests
Antimicrobial resistance (AMR) is an ancient phenomenon (D'Costa et al., 2011) where microorganisms have evolved strategie...
Sugar phosphatases as biocatalysts for biomanufacturing: Recent advances and applications
The haloacid dehydrogenase (HAD) superfamily is an evolutionarily diverse, widely distributed, and abundant class of enzym...
Protease engineering: Approaches, tools, and emerging trends
Proteases catalyze one of the most fundamental biochemical reactions: the hydrolysis of peptide bonds in peptides and prot...
Enzymatic de novo oligonucleotide synthesis: Emerging techniques and advancements
Oligonucleotide synthesis serves as a cornerstone of modern life sciences, enabling groundbreaking advancements across mol...
Engineering catalytically promiscuous enzymes to serve new functions
Enzymes are powerful biological catalysts used in the manufacturing of diverse chemicals and pharmaceuticals due to their ...
Advances in in vitro cultivation techniques for comprehensive analysis of human gut microbiome
The human gut microbiota is a diverse community of prokaryotic and eukaryotic microorganisms closely associated with the h...
Enzyme miniaturization: Revolutionizing future biocatalysts
Enzyme miniaturization offers a transformative approach to overcome limitations posed by the large size of conventional en...
Innovations in smart enzyme biosensors: Advancing the detection of antibiotic residues in aquaculture
With the rapid development of aquaculture, disease-induced mortality has emerged as a significant hurdle, posing unpredict...
Load More
format_indent_increase