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TRIM3 Suppresses Tumor Progression in Non-small-Cell Lung Cancer by Promoting PD-L1 Ubiquitination and Degradation
TRIM3 Suppresses Tumor Progression in Non-small-Cell Lung Cancer by Promoting PD-L1 Ubiquitination and Degradation
Our objective was to investigate TRIM3 expression and its role in the immune microenvironment of non-small-cell lung cance...
Sentinel Lymph Node Biopsy for Desmoplastic Melanoma: A Systematic Review and Meta-analysis
Sentinel Lymph Node Biopsy for Desmoplastic Melanoma: A Systematic Review and Meta-analysis
The propensity of desmoplastic melanoma (DM) to spread to regional lymph nodes remains disputed, creating uncertainty rega...
Hepatic Artery Infusion Pump Chemotherapy Associated Biliary Sclerosis After Treatment for Colorectal Cancer Liver Metastasis
Hepatic Artery Infusion Pump Chemotherapy Associated Biliary Sclerosis After Treatment for Colorectal Cancer Liver Metastasis
Hepatic artery infusion pump chemotherapy (HAIC) improves colorectal liver metastasis (CRLM) outcomes, but treatment-assoc...
Colloid Carcinoma of the Pancreas: A Distinct and Less Aggressive Entity in the Spectrum of Pancreatic Malignancies
Colloid Carcinoma of the Pancreas: A Distinct and Less Aggressive Entity in the Spectrum of Pancreatic Malignancies
Pancreatic colloid carcinoma (CC) is a rare subtype of invasive carcinoma arising from intraductal papillary mucinous neop...
The Margin of the Largest Tumor Predicts Overall Survival After Resection of Multitumor Colorectal Liver Metastases
The Margin of the Largest Tumor Predicts Overall Survival After Resection of Multitumor Colorectal Liver Metastases
Resection is a potentially curative treatment for colorectal liver metastasis (CRLM). In multitumor CRLM cases, closest ma...
Noninvasive Tests for Liver Fibrosis Predict Postoperative Complications After Resection of Colorectal Liver Metastases
Noninvasive Tests for Liver Fibrosis Predict Postoperative Complications After Resection of Colorectal Liver Metastases
Colorectal liver metastases (CRLM) occur in up to 50% of patients who suffer from colorectal cancer. While liver resection...
Conversion Surgery After Induction Therapy for Initially Unresectable Stage III Non-small Cell Lung Cancer: A Proof-of-Concept Trial
Conversion Surgery After Induction Therapy for Initially Unresectable Stage III Non-small Cell Lung Cancer: A Proof-of-Concept Trial
To prove the concept of conversion surgery after induction therapy in initially unresectable stage III non-small-cell lung...
Evaluation of Diagnostic Accuracy of Preoperative CT-Based Radiomics in Primary Retroperitoneal Sarcoma
Evaluation of Diagnostic Accuracy of Preoperative CT-Based Radiomics in Primary Retroperitoneal Sarcoma
Obtaining an accurate preoperative diagnosis in retroperitoneal sarcoma (RPS) is challenging, and radiomics-based models m...
Endoscopic Image-Based Prediction of Esophageal Stenosis after ESD Using Mucosal Defect Metrics
Endoscopic Image-Based Prediction of Esophageal Stenosis after ESD Using Mucosal Defect Metrics
Stricture is a major adverse event following esophageal endoscopic submucosal dissection (ESD). Although postoperative eso...
Evaluating Variation in Lymph Node Sampling During Sentinel Lymph Node Biopsy for Melanoma
Evaluating Variation in Lymph Node Sampling During Sentinel Lymph Node Biopsy for Melanoma
The operative standard for melanoma, implemented by the Commission on Cancer (CoC), addresses margin width and excision de...
Oncologic Outcomes of Intraoperative Autologous Blood Transfusion for Major Oncologic Resection
Oncologic Outcomes of Intraoperative Autologous Blood Transfusion for Major Oncologic Resection
Intraoperative autologous blood transfusion (IABT) is contraindicated during oncologic resection owing to concern for meta...
Mapping Current Research Status and Emerging Frontiers of T-Cell Exhaustion: A Comprehensive Data-Mining-Based Study
Mapping Current Research Status and Emerging Frontiers of T-Cell Exhaustion: A Comprehensive Data-Mining-Based Study
T-cell exhaustion (Tex) represents a distinct immunological state characterized by the progressive functional deterioratio...
Response-Adapted Oncologic Surgery in Cutaneous Squamous Cell Carcinoma: A Paradigm Shift Following Neoadjuvant Immunotherapy
Response-Adapted Oncologic Surgery in Cutaneous Squamous Cell Carcinoma: A Paradigm Shift Following Neoadjuvant Immunotherapy
Recent studies suggested that neoadjuvant cemiplimab can achieve a significant pathologic response in patients with cutane...
Postoperative Step Count Predicts Unplanned Readmission After Radical Esophagectomy: A Retrospective Cohort Study
Postoperative Step Count Predicts Unplanned Readmission After Radical Esophagectomy: A Retrospective Cohort Study
Unplanned readmission after esophagectomy is associated with increased health care costs and poorer survival outcomes. Pos...
Mesenteric Route Superior Mesenteric Artery First Approach in Robot-Assisted Pancreatoduodenectomy
Mesenteric Route Superior Mesenteric Artery First Approach in Robot-Assisted Pancreatoduodenectomy
The superior mesenteric artery (SMA) approach is crucial for the successful implementation of robot-assisted pancreatoduod...
The Landmark Series: Neoadjuvant Radiotherapy in Extremity Soft Tissue Sarcoma—The Way to Hypofractionation
The Landmark Series: Neoadjuvant Radiotherapy in Extremity Soft Tissue Sarcoma—The Way to Hypofractionation
For patients with nonmetastatic soft tissue sarcoma (STS) who are at high risk of local recurrence, the standard of care f...
ARID4B Promotes the Progression of Hepatocellular Carcinoma Through the PI3K/AKT Pathway
ARID4B Promotes the Progression of Hepatocellular Carcinoma Through the PI3K/AKT Pathway
AT-rich interaction domain 4B (ARID4B) is a transcriptional activator that regulates the phosphatidylinositol 3-kinase (PI...
ASO Author Reflections: Preoperative Assessment of Nodal Burden in Breast Cancer
ASO Author Reflections: Preoperative Assessment of Nodal Burden in Breast Cancer
Kalinsky K, et al. 21-Gene assay to inform chemotherapy benefit in node-positive breast cancer. N Engl J Med. 2021;385(25)...