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How to use an extensive Flammer syndrome phenotyping for a holistic protection against health-to-disease transition — facts and practical recommendations
How to use an extensive Flammer syndrome phenotyping for a holistic protection against health-to-disease transition — facts and practical recommendations
Due to their phenotype-associated attitude predominantly oriented towards high performance, Flammer syndrome (FS) phenotyp...
Multivariable data-driven framework of predictive, preventive, and personalized medicine for long-term atrial fibrillation risk in patients with new-onset obstructive sleep apnea
Multivariable data-driven framework of predictive, preventive, and personalized medicine for long-term atrial fibrillation risk in patients with new-onset obstructive sleep apnea
Atrial fibrillation (AF) presents a significant challenge in patients with obstructive sleep apnea (OSA), as traditional r...
Enhancing cardiovascular risk prediction in hypertensive adults: a 3PM-based evaluation of insulin resistance and arterial stiffness
Enhancing cardiovascular risk prediction in hypertensive adults: a 3PM-based evaluation of insulin resistance and arterial stiffness
Hypertension management remains challenging due to coexisting insulin resistance (IR) and arterial stiffness—two sil...
in noncommunicable disease management: therapeutic prospects within the PPPM framework
in noncommunicable disease management: therapeutic prospects within the PPPM framework
Non-communicable diseases (NCDs), including cardiovascular diseases, respiratory disorders, And age-related degenerative d...
Explainable multiomic screening for suboptimal health status in young adults: 3PM-guided innovation is envisaged
Explainable multiomic screening for suboptimal health status in young adults: 3PM-guided innovation is envisaged
Suboptimal health status (SHS) is a reversible predisease stage and represents a key “window of opportunity” f...
The use of predictive, preventive, and personalized medical approaches to optimize hypertension management
The use of predictive, preventive, and personalized medical approaches to optimize hypertension management
Hypertension, a major modifiable risk factor for cardiovascular disease, exhibits significant heterogeneity due to genetic...
Bidirectional associations between kidney function decline and carotid plaque progression: a longitudinal cohort study in the context of predictive, preventive, and personalised medicine
Bidirectional associations between kidney function decline and carotid plaque progression: a longitudinal cohort study in the context of predictive, preventive, and personalised medicine
Atherosclerosis and chronic kidney disease are major contributors to cardiovascular disease (CVD) and premature mortality ...
Glioma angiogenesis phosphoproteome landscape and biomarker sets identified with phenome-centered multiomics toward 3P medical approaches
Glioma angiogenesis phosphoproteome landscape and biomarker sets identified with phenome-centered multiomics toward 3P medical approaches
Protein phosphorylation is an important molecular event in tumor angiogenesis that is a canonical hallmark in glioma. We h...
Multimodal AI-based modeling of glaucoma progression: a 3PM-guided approach integrating structural, functional, and vascular patterns
Multimodal AI-based modeling of glaucoma progression: a 3PM-guided approach integrating structural, functional, and vascular patterns
Glaucoma remains the leading cause of irreversible blindness worldwide. The development of predictive, preventive, and per...
Global, regional, and Chinese disease burden and trends of colorectal cancer, 1990–2021: An update from the GBD 2021 study and implications for predictive, preventive, and personalized medicine
Global, regional, and Chinese disease burden and trends of colorectal cancer, 1990–2021: An update from the GBD 2021 study and implications for predictive, preventive, and personalized medicine
In the era of shifting healthcare, a “reactive” approach to colorectal cancer (CRC) management—that is, ...
Repurposing holistic effects of metformin from diabetes management to skin wound healing: a 3PM-guided innovation
Repurposing holistic effects of metformin from diabetes management to skin wound healing: a 3PM-guided innovation
Metformin has recently garnered attention for its unique role in cellular metabolism regulation, prompting investigations ...
Gut microbiota in hepatic encephalopathy: a 3PM-guided three-tier health strategy
Gut microbiota in hepatic encephalopathy: a 3PM-guided three-tier health strategy
Hepatic encephalopathy is one of the most severe complications of liver cirrhosis, with a high mortality rate following it...
Validated semi-supervised early and accurate screening for anterior segment diseases: a 3PM-guided conceptual and technological innovation
Validated semi-supervised early and accurate screening for anterior segment diseases: a 3PM-guided conceptual and technological innovation
Ocular anterior segment diseases are major causes of global visual impairment. Early and accurate detection of anterior se...
Synergistic effects of circulating monocyte accumulation and cardiometabolic abnormalities on all-cause mortality: implications for predictive, preventive and personalised medicine
Synergistic effects of circulating monocyte accumulation and cardiometabolic abnormalities on all-cause mortality: implications for predictive, preventive and personalised medicine
Chronic monocytosis and enhanced hematopoietic activity are increasingly recognized as core features of immune–metab...
Innovative mitochondria-based holistic 3PM approach to female health status: Facts and outlook
Innovative mitochondria-based holistic 3PM approach to female health status: Facts and outlook
Throughout a woman’s life, energy metabolism faces more volatile demands compared to men, driven by major hormonal t...
Delivery systems in the diagnosis and treatment of chronic atrophic gastritis: A Three-Level health strategy guided by 3PM
Delivery systems in the diagnosis and treatment of chronic atrophic gastritis: A Three-Level health strategy guided by 3PM
Chronic atrophic gastritis with accelerated progression represents a major risk factor for gastric cancer development, pri...
Transforming telemedicine through predictive, preventive, and personalized medicine (PPPM): innovations, challenges, and future directions
Transforming telemedicine through predictive, preventive, and personalized medicine (PPPM): innovations, challenges, and future directions
Telemedicine, a patient-centric innovative healthcare delivery model, leverages advanced telecommunication technologies to...
Triglyceride glucose index and modified triglyceride glucose indices are instrumental to optimize 3P medical management for postpartum cardiovascular disease
Triglyceride glucose index and modified triglyceride glucose indices are instrumental to optimize 3P medical management for postpartum cardiovascular disease
Postpartum cardiovascular disease (CVD) following hypertensive disorders of pregnancy (HDP) involves multifactorial mechan...
AI-enabled predictive, preventive and personalised oral health management: a lightweight patient-centred model for automated assessment of dental plaque and gingival inflammation
AI-enabled predictive, preventive and personalised oral health management: a lightweight patient-centred model for automated assessment of dental plaque and gingival inflammation
Periodontal diseases are highly prevalent and largely preventable. The challenge of ensuring sustained adherence to preven...
The interplay between antihypertensive medication and lifestyle with cardiovascular outcomes in patients with hypertension: the PURE-China study
The interplay between antihypertensive medication and lifestyle with cardiovascular outcomes in patients with hypertension: the PURE-China study
Although antihypertensive medication is central to hypertension management, substantial residual risks persist. This study...
Physical activity, cardiovascular disease, and mortality across obesity levels
Physical activity, cardiovascular disease, and mortality across obesity levels
High physical activity (PA) is associated with decreased risk of cardiovascular disease (CVD) and mortality. However, whet...
Prediction of risk for isolated incomplete lateral meniscal injury using a dynamic nomogram based on MRI-derived anatomic radiomics and physical activity: a proof-of-concept study in 3PM-guided management
Prediction of risk for isolated incomplete lateral meniscal injury using a dynamic nomogram based on MRI-derived anatomic radiomics and physical activity: a proof-of-concept study in 3PM-guided management
The 3PM framework revolutionizes disease management by facilitating early risk prediction, disease prevention, and persona...
Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials in the context of prediction, prevention, and a personalized medicine framework
Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials in the context of prediction, prevention, and a personalized medicine framework
Metabolic-associated fatty liver disease (MASLD) is a growing global health concern. From the standpoint of preventive and...
Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria
Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria
Metabolomics measurements of eccrine sweat may provide novel and relevant biomedical information to support predictive, pr...
Mitochondria in cutaneous health, disease, ageing and rejuvenation—the 3PM-guided mitochondria-centric dermatology
Mitochondria in cutaneous health, disease, ageing and rejuvenation—the 3PM-guided mitochondria-centric dermatology
Association of both intrinsic and extrinsic risk factors leading to accelerated skin ageing is reflected in excessive ROS ...
Advancing predictive, preventive, and personalized medicine in eyelid diseases: a concerns-based and expandable screening system through structural dissection
Advancing predictive, preventive, and personalized medicine in eyelid diseases: a concerns-based and expandable screening system through structural dissection
Early recognition of eyelid morphological abnormalities was crucial, as untreated conditions could lead to blinding compli...
Characterization of the gut microbiota in drug abuse: prediction, prevention, and personalized medicine to benefit affected populations
Characterization of the gut microbiota in drug abuse: prediction, prevention, and personalized medicine to benefit affected populations
Drug abuse poses an enormous threat to global public health. Long-term drug abuse can reduce the quality of life of patien...
Monoclonal antibody immune therapy response instrument for stratification and cost-effective personalized approaches in 3PM-guided pan cancer management
Monoclonal antibody immune therapy response instrument for stratification and cost-effective personalized approaches in 3PM-guided pan cancer management
Immune checkpoint inhibitors (ICIs), such as anti-PD-1, anti-PD-L1, and anti-CTLA-4 therapies, have revolutionized cancer ...
Microalgae and exercise: from molecular mechanisms and brain health to clinical perspectives in the context of 3P medicine
Microalgae and exercise: from molecular mechanisms and brain health to clinical perspectives in the context of 3P medicine
Microalgae are emerging as innovative bioresources with diverse therapeutic applications, particularly in cardiovascular h...
Acute mountain sickness prediction: a concerto of multidimensional phenotypic data and machine learning strategies in the framework of predictive, preventive, and personalized medicine
Acute mountain sickness prediction: a concerto of multidimensional phenotypic data and machine learning strategies in the framework of predictive, preventive, and personalized medicine
Acute mountain sickness (AMS) is a self-limiting illness, involving a complex series of physiological responses to rapid a...
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