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Mechanisms and clinical progress of adipose-derived stem cells and their derivatives in the treatment of hair loss
Mechanisms and clinical progress of adipose-derived stem cells and their derivatives in the treatment of hair loss
The rising prevalence of alopecia poses a significant challenge for both clinicians and researchers. As the global inciden...
HMGB1 as an emerging key modulator of bone remodeling: a narrative review
HMGB1 as an emerging key modulator of bone remodeling: a narrative review
Bone is a dynamic tissue that undergoes microdamage and requires remodeling to replace old bone matrix. This process deman...
Mesenchymal stromal cells conditioned by peripheral blood mononuclear cells exert enhanced immunomodulation capacities and alleviate a model of Myasthenia Gravis
Mesenchymal stromal cells conditioned by peripheral blood mononuclear cells exert enhanced immunomodulation capacities and alleviate a model of Myasthenia Gravis
Mesenchymal Stromal Cells (MSC) possess innate immunomodulatory properties, which can be significantly enhanced through co...
Correction: DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy
Correction: DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
Trained human bone marrow mesenchymal stem cells restore tissue immuno-microenvironment in fulminant hepatic failure mice
Trained human bone marrow mesenchymal stem cells restore tissue immuno-microenvironment in fulminant hepatic failure mice
Trained immunity with human bone marrow mesenchymal stem cells (hBMSC) is a promising approach to liver regeneration. This...
Long-term therapeutic effects of allogeneic mesenchymal stem cell transplantation for intrauterine adhesions
Long-term therapeutic effects of allogeneic mesenchymal stem cell transplantation for intrauterine adhesions
Intrauterine adhesion (IUA), resulting from uterine trauma, is one of the major causes of female infertility. Previous stu...
Preclinical study of novel human allogeneic adipose tissue-derived mesenchymal stem cell sheets toward a first-in-human clinical trial for myopic chorioretinal atrophy
Preclinical study of novel human allogeneic adipose tissue-derived mesenchymal stem cell sheets toward a first-in-human clinical trial for myopic chorioretinal atrophy
Mesenchymal stem cells may have neuroprotective and tissue regenerative capabilities and the potential to rescue retinal d...
Generation of vascularized pancreatic progenitors through co-differentiation of endoderm and mesoderm from human pluripotent stem cells
Generation of vascularized pancreatic progenitors through co-differentiation of endoderm and mesoderm from human pluripotent stem cells
The simultaneous differentiation of human pluripotent stem cells (hPSCs) into both endodermal and mesodermal lineages is c...
Correction: Vitamin C facilitates direct cardiac reprogramming by inhibiting reactive oxygen species
Correction: Vitamin C facilitates direct cardiac reprogramming by inhibiting reactive oxygen species
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model
Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model
Sporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, is a fatal neurodegenerative disease with ...
CRX haploinsufficiency compromises photoreceptor precursor translocation and differentiation in human retinal organoids
CRX haploinsufficiency compromises photoreceptor precursor translocation and differentiation in human retinal organoids
The CRX-associated autosomal dominant retinopathies suggest a possible pathogenic mechanism of gene haploinsufficiency. Ho...
Emerging role of mesenchymal stromal cells in gynecologic cancer therapy
Emerging role of mesenchymal stromal cells in gynecologic cancer therapy
Mesenchymal stromal cells (MSCs) show considerable promise in regenerative medicine with superior anti-fibrotic, immunomod...
Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease
Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease
Genomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified...
The effect of TLR3 priming conditions on MSC immunosuppressive properties
The effect of TLR3 priming conditions on MSC immunosuppressive properties
Mesenchymal stromal cells (MSCs) have regenerative and immunomodulatory properties, making them suitable for cell therapy....
Induced pluripotent stem cells modulate the Wnt pathway in the bleomycin-induced model of idiopathic pulmonary fibrosis
Induced pluripotent stem cells modulate the Wnt pathway in the bleomycin-induced model of idiopathic pulmonary fibrosis
The Wnt signaling pathway has been implicated in the pathogenesis of fibrotic disorders and malignancies. Hence, we aimed ...
Deciphering the role of extrachromosomal circular DNA in adipose stem cells from old and young donors
Deciphering the role of extrachromosomal circular DNA in adipose stem cells from old and young donors
The functional impairment of adipose stem cells (ASCs) during aging limits their clinical transformation. Studies have sho...
Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells
Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells
Epithelial–mesenchymal transition (EMT) is a cell remodeling process in which epithelial cells undergo a reversible ...
Adipose-derived mesenchymal stem cells cultured in serum-free medium attenuate acute contrast-induced nephropathy by exerting anti-apoptotic effects
Adipose-derived mesenchymal stem cells cultured in serum-free medium attenuate acute contrast-induced nephropathy by exerting anti-apoptotic effects
Contrast-induced nephropathy (CIN) is a major clinical problem associated with acute kidney injury during hospitalization....
Correction: Mesenchymal stem cell-secreted prostaglandin E2 ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization
Correction: Mesenchymal stem cell-secreted prostaglandin E2 ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases
Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases
Inherited retinal diseases (IRDs) can induce severe sight-threatening retinal degeneration and impose a considerable econo...
Disclosing the molecular profile of the human amniotic mesenchymal stromal cell secretome by filter-aided sample preparation proteomic characterization
Disclosing the molecular profile of the human amniotic mesenchymal stromal cell secretome by filter-aided sample preparation proteomic characterization
The secretome of mesenchymal stromal cells isolated from the amniotic membrane (hAMSCs) has been extensively studied for i...
HIF-1α promotes kidney organoid vascularization and applications in disease modeling
HIF-1α promotes kidney organoid vascularization and applications in disease modeling
Kidney organoids derived from human pluripotent stem cells (HiPSCs) hold huge applications for drug screening, disease mod...
The influence of inflammation on the characteristics of adipose-derived mesenchymal stem cells (ADMSCs) and tissue repair capability in a hepatic injury mouse model
The influence of inflammation on the characteristics of adipose-derived mesenchymal stem cells (ADMSCs) and tissue repair capability in a hepatic injury mouse model
Mesenchymal stem cells (MSCs) are adult stem cells with self-renewal and multi-directional differentiation potential and p...
Lactate: an alternative pathway for the immunosuppressive properties of mesenchymal stem/stromal cells
Lactate: an alternative pathway for the immunosuppressive properties of mesenchymal stem/stromal cells
The metabolic reprogramming of mesenchymal stem/stromal cells (MSC) favoring glycolysis has recently emerged as a new appr...
The effects of intraovarian injection of autologous menstrual blood-derived mesenchymal stromal cells on pregnancy outcomes in women with poor ovarian response
The effects of intraovarian injection of autologous menstrual blood-derived mesenchymal stromal cells on pregnancy outcomes in women with poor ovarian response
Assisted reproduction faces a significant obstacle in the form of poor ovarian response (POR) to controlled ovarian stimul...
Synergistic effect of chitosan-alginate composite hydrogel enriched with ascorbic acid and alpha-tocopherol under hypoxic conditions on the behavior of mesenchymal stem cells for wound healing
Synergistic effect of chitosan-alginate composite hydrogel enriched with ascorbic acid and alpha-tocopherol under hypoxic conditions on the behavior of mesenchymal stem cells for wound healing
In regenerative medicine, especially skin tissue engineering, the focus is on enhancing the quality of wound healing. Also...
Extracellular vesicles derived from human ESC–MSCs target macrophage and promote anti-inflammation process, angiogenesis, and functional recovery in ACS-induced severe skeletal muscle injury
Extracellular vesicles derived from human ESC–MSCs target macrophage and promote anti-inflammation process, angiogenesis, and functional recovery in ACS-induced severe skeletal muscle injury
Acute compartment syndrome (ACS) is one of the most common complications of musculoskeletal injury, leading to the necrosi...
ADSC secretome constrains NK cell activity by attenuating IL-2-mediated JAK-STAT and AKT signaling pathway via upregulation of CIS and DUSP4
ADSC secretome constrains NK cell activity by attenuating IL-2-mediated JAK-STAT and AKT signaling pathway via upregulation of CIS and DUSP4
Mesenchymal stem cells (MSCs) have immunomodulatory properties and therapeutic effects on autoimmune diseases through thei...
Bright ferritin for long-term MR imaging of human embryonic stem cells
Bright ferritin for long-term MR imaging of human embryonic stem cells
A non-invasive imaging technology that can monitor cell viability, retention, distribution, and interaction with host tiss...
Human mesenchymal stem cells derived from adipose tissue showed a more robust effect than those from the umbilical cord in promoting corneal graft survival by suppressing lymphangiogenesis
Human mesenchymal stem cells derived from adipose tissue showed a more robust effect than those from the umbilical cord in promoting corneal graft survival by suppressing lymphangiogenesis
Mesenchymal stem cells (MSCs) have shown promising potential in allograft survival. However, few reports have focused on c...
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