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S100-positive stroma in salivary gland basal cell adenoma: recent progress and future perspectives
S100-positive stroma in salivary gland basal cell adenoma: recent progress and future perspectives
Basal cell adenoma (BCA) with S100-positive stroma exhibits tricellular differentiation, consisting of bilayered epithelia...
Albert Eulenburg (1840–1917)
Albert Eulenburg (1840–1917)
Albert Eulenburg (Fig. 1) was born in Berlin on August 10, 1840, into the Jewish fami...
Uiberrak, Barbara (1902–1979)
Uiberrak, Barbara (1902–1979)
Barbara Uiberrak studierte Medizin und spezialisierte sich anschließend im Fach Pathologie. Sie trat 1933 in die NSDA...
In memoriam Archinto P Anzil (29th January 1930–22nd January 2026)
In memoriam Archinto P Anzil (29th January 1930–22nd January 2026)
Anzil AP, Bieser A, Wernig A (1984) Light and electron microscopic identification of nerve terminal sprouting and retracti...
Forschungsgeschichte
Forschungsgeschichte
Die Geschichte der wissenschaftlichen Auseinandersetzung mit Thomas Manns Roman Der Zauberberg ist ebenso umfangreich und ...
Histologic Dataset of Normal and Atypical Mitotic Figures on Human Breast Cancer (AMi-Br)
Histologic Dataset of Normal and Atypical Mitotic Figures on Human Breast Cancer (AMi-Br)
Assessment of the density of mitotic figures (MFs) in histologic tumor sections is an important prognostic marker for many...
Annual Review Issues
Each year Virchows Archiv publishes an annual review issue on a unique topic. Past issues have included breast pathology, ...
Adnexal carcinoma with fusion: a third case
Adnexal carcinoma with fusion: a third case
Ethics approval The local Ethics Committee in Human Researc...
VIAR Best Paper Award for Young Investigator
Virchows Archiv and the European Society of Pathology (ESP) wish to recognize the outstanding work that is being published...
VIAR Best Paper Award
Each year at the European Society of Pathology's Annual Congress an awarded is presented the Virchows Archiv Best Pap...
Diagnostic relevance of p53 and Rb status in neuroendocrine tumors G3 from different organs: an immunohistochemical study of 465 high-grade neuroendocrine neoplasms
Diagnostic relevance of p53 and Rb status in neuroendocrine tumors G3 from different organs: an immunohistochemical study of 465 high-grade neuroendocrine neoplasms
The double inactivation of TP53 and RB1 is considered typical of neuroendocrine carcinomas (NECs) but is assumed to be rar...
Julius Hirschberg und die Geschichte der Augenheilkunde
Julius Hirschberg und die Geschichte der Augenheilkunde
Die Werke von Julius Hirschberg (1843–1925), insbesondere seine „Geschichte der Augenheilkunde“ sind bis...
GLI1::FOXO4-rearranged kidney tumors: a potentially distinct renal subtype within the spectrum of GLI1-altered tumors?
GLI1::FOXO4-rearranged kidney tumors: a potentially distinct renal subtype within the spectrum of GLI1-altered tumors?
Pathogenic alterations, namely, fusions and amplifications, of the GLI1 gene have been identified in various mesenchymal t...
Rhabdomyosarcoma in children and young adults
Rhabdomyosarcoma in children and young adults
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood, accounting for 3% of all pediatric malignan...
Primary cutaneous rhabdomyosarcoma with EWSR1/FUS::TFCP2 fusion: four new cases with distinctive morphology, immunophenotypic, and genetic profile
Primary cutaneous rhabdomyosarcoma with EWSR1/FUS::TFCP2 fusion: four new cases with distinctive morphology, immunophenotypic, and genetic profile
EWSR1/FUS::TFCP2-rearranged rhabdomyosarcoma (RMS) is a rare tumor with an aggressive clinical course, a predilection for ...
Interstitial lipoid pneumonia—A complication of intravenous administration of lipid emulsions in critically ill patients
Interstitial lipoid pneumonia—A complication of intravenous administration of lipid emulsions in critically ill patients
Lipoid pneumonia is a rare entity most often associated with inhalation of foreign material (i.e. “fire-eater’...
Prognosis and tumor microenvironment in pseudohypoxic pheochromocytoma/paraganglioma
Prognosis and tumor microenvironment in pseudohypoxic pheochromocytoma/paraganglioma
Pheochromocytoma and paraganglioma (PPGL) are rare tumors that occur in the adrenal medulla and extra-adrenal tissues, res...
Pediatric lymphomas: overview and diagnostic challenges
Pediatric lymphomas: overview and diagnostic challenges
Only 10% of new lymphoma diagnoses in the USA occur in children < 15 years. Although the same ...
Prostatic amyloidosis: pathological features of an underdiagnosed condition
Prostatic amyloidosis: pathological features of an underdiagnosed condition
Amyloidosis is a rare disease that can affect genitourinary organs but the involvement of the prostate has been documented...
S100-positive stroma in salivary gland basal cell adenomas: a neoplastic component with CTNNB1 mutations
S100-positive stroma in salivary gland basal cell adenomas: a neoplastic component with CTNNB1 mutations
Basal cell adenomas (BCAs) are benign epithelial tumors of the salivary gland, characterized by the proliferation of basal...
Cystic masses of the pediatric lung: update on congenital pulmonary airway malformation and its differential diagnosis
Cystic masses of the pediatric lung: update on congenital pulmonary airway malformation and its differential diagnosis
Localized cystic lung lesions in pediatric patients encompass a spectrum of benign and rare malignant conditions that are ...
EGFR status assessment using reflex testing targeted next-generation sequencing for resected non-squamous non-small cell lung cancer
EGFR status assessment using reflex testing targeted next-generation sequencing for resected non-squamous non-small cell lung cancer
EGFR status assessment is mandatory for adjuvant decision-making of resected stage IB-IIIA non-squamous non-small cell lun...
YAP1::TFE3 fusion in a case of malignant TFE3-rearranged PEComa of the lung: expanding the spectrum of pulmonary PEComa-like mesenchymal neoplasms
YAP1::TFE3 fusion in a case of malignant TFE3-rearranged PEComa of the lung: expanding the spectrum of pulmonary PEComa-like mesenchymal neoplasms
The family of PEComa encompasses a heterogeneous group of related mesenchymal neoplasms with myomelanocytic differentiatio...
Prevalence and interpretation of AFF immunostain of DEK::AFF2 fusion-associated papillary squamous cell carcinoma in a retrospective cohort of recurrent sinonasal papillomas
Prevalence and interpretation of AFF immunostain of DEK::AFF2 fusion-associated papillary squamous cell carcinoma in a retrospective cohort of recurrent sinonasal papillomas
DEK::AFF2 fusion-associated papillary squamous cell carcinoma is a novel entity characterized by its unique translocation ...
SATB2, CKAE1/AE3, and synaptophysin as a sensitive immunohistochemical panel for the detection of lymph node metastases of Merkel cell carcinoma
SATB2, CKAE1/AE3, and synaptophysin as a sensitive immunohistochemical panel for the detection of lymph node metastases of Merkel cell carcinoma
Histopathological evaluation of lymph nodes in Merkel cell carcinoma has become crucial in progression estimation and trea...
Correction to: HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Correction to: HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Postponing evolution: why are we choosing to ignore the need for a digital transformation in pathology?
Postponing evolution: why are we choosing to ignore the need for a digital transformation in pathology?
For some years now, practical evidence on the benefits of using whole slide images (W...
Letter to the editor on Donzel M et al. “Androgenetic/biparental mosaicism in a diploid mole-like conceptus: report of a case with triple paternal contribution”
Letter to the editor on Donzel M et al. “Androgenetic/biparental mosaicism in a diploid mole-like conceptus: report of a case with triple paternal contribution”
Donzel M, Gaillot-Durand L, Joubert M, Aziza J, Beneteau C, Mauduit C, Ploteau S, Hajri T, Bolze PA, Massardier J, Devouas...
„Rasse“ als globaler Datenstrom: Die Hamburger Anthropologie des 20. Jahrhunderts als Ausgangspunkt einer Datengeschichte der Rassifizierung
„Rasse“ als globaler Datenstrom: Die Hamburger Anthropologie des 20. Jahrhunderts als Ausgangspunkt einer Datengeschichte der Rassifizierung
Dieser Aufsatz zeigt anhand der Hamburger Anthropologie des 20. Jahrhunderts, wie historisch spezifische Aufschre...
Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
The impact of tumor focality on prostate cancer (PCa) prognosis has been addressed in several studies with conflicting res...
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