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Editorial: Honoring Dr. Angelo Azzi's legacy and expanding the horizons of Molecular Aspects of Medicine
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Advances in sperm transcription and translation activities: From traditional views to new discoveries
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Viral triggers and genetic predisposition in ocular autoimmunity: unraveling the breakdown of immune privilege and advancing targeted therapeutics
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Protein kinase D: Integrating cancer and metabolic disorders
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Impact of type 2 diabetes on malignancies of the female reproductive system
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The multiorgan crosstalk network of the liver-brain axis: From molecular mechanisms to emerging therapeutic targets
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Insulin resistance: The central node of convergence between unfolded protein response, diabetes, and cancer
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Metabolic dysregulation: Its role in diabetes mellitus and cancers
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Translational readthrough using TRIDs - Achievements and challenges for the treatment of inherited retinal disorders
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CRISPR as a therapeutic tool for inherited retinal degenerations: Advances, challenges, and future directions
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Dual-targeting strategies for cancer and diabetes: Converging pharmacological pathways and repurposed therapies
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Glucagon-like peptide-1 receptor agonists across anti-inflammation
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Advancing precision medicine in pancreatic cancer using novel biomarkers and clinical targets
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RNA editing of pathogenic variants causing inherited retinal diseases using endogenous ADAR-current and future perspectives
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Liver aging: underlying mechanisms and therapeutic strategies
Population aging has emerged as a dominant global trend, accompanied by a progressive decline in physiological functions a...
Molecular mechanism involved in sarcopenia and frailty, diagnosis and therapy
Volume 105, October 2025, 101387Author links open overlay panelJose Viña, Maria Carmen Gomez-CabreraShow moreThis article ...
Evolution of the incidence of male fertility disorders over the last decades
Volume 105, October 2025, 101398Author links open overlay panel, , , , , AbstractMale reproductive health evaluation invol...
Mitophagy: A key regulator of radiotherapy resistance in the tumor immune microenvironment
Cancer remains one of the leading causes of death worldwide (Wu et al., 2020). Recent global estimates report approximatel...
Unveiling the P2X7 receptor: Exploring its mechanisms, pathogenic role in ocular diseases, and emerging therapeutic potential
Purinergic receptors, particularly P2X receptors, have been a focus of extensive research originating from three distinct ...
Optogenetic tools and their applications for therapeutic intervention in end-stage inherited retinal diseases
Volume 105, October 2025, 101388Author links open overlay panel, , AbstractRetinal degenerative diseases pose significant ...
Viral and non-viral vectors for gene therapy in the treatment of bone-related disorders: molecular insights and clinical perspectives
The field of orthopedic medicine grapples with a significant clinical gap in the treatment of both chronic and acute bone ...
Urogenital manifestations of SARS-CoV-2, MPXV and Zika virus: A comprehensive review
The current century has been associated with the outbreaks of emerging and re-emerging viral infections with significant c...
Research advancements on sumoylation in gastrointestinal cancers
SUMOylation, as a key post-translational modification mechanism, precisely regulates protein function, stability and subce...
Influence of microbiota composition on the pathogenesis of type 2 diabetes: Physiological aspects
Volume 106, December 2025, 101410Author links open overlay panel, , , , , , , , , AbstractThe development of type 2 diabet...
The ocular immune system and Flaviviruses: A crossroad between defense and disease
Flaviviruses constitute a group of small enveloped viruses with positive-sense single stranded RNA genomes of approximatel...
Immunomodulation: A new approach to cancer cachexia, potentially suitable for aging
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Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets
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Diet and exercise in frailty and sarcopenia. Molecular aspects
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Impacts of cancer therapy on male fertility: Past and present
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Advances in human In vitro spermatogenesis: A review
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