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Exploring the impact of ADIPOQ gene variants on plasma adiponectin levels and oxidative stress in type 2 diabetes mellitus and diabetic nephropathy in South Indian population: a case–control study
Exploring the impact of ADIPOQ gene variants on plasma adiponectin levels and oxidative stress in type 2 diabetes mellitus and diabetic nephropathy in South Indian population: a case–control study
Diabetic nephropathy (DN) is a significant and major microvascular complication of Type 2 diabetes mellitus (T2DM) with ob...
Effect of tofogliflozin on obesity-related health problems in patients with type 2 diabetes and overweight or obesity—a post-hoc sub-analysis of the UTOPIA study
Effect of tofogliflozin on obesity-related health problems in patients with type 2 diabetes and overweight or obesity—a post-hoc sub-analysis of the UTOPIA study
This study aimed to evaluate the effects of tofogliflozin, a sodium-glucose cotransporter 2 inhibitor, on health issues in...
Association of impaired awareness of hypoglycemia and real-time continuous glucose monitoring with the occurrence and frequency of severe hypoglycemia in adults with type 1 diabetes mellitus: a real-world panel data analysis from the PR-IAH study
Association of impaired awareness of hypoglycemia and real-time continuous glucose monitoring with the occurrence and frequency of severe hypoglycemia in adults with type 1 diabetes mellitus: a real-world panel data analysis from the PR-IAH study
Patients with long-standing type 1 diabetes mellitus (T1DM) often experience severe hypoglycemia (SH); however, the protec...
Role of metallothionein 3 in diabetic nephropathy via interplay with HIF-1α
Role of metallothionein 3 in diabetic nephropathy via interplay with HIF-1α
Metallothioneins (MTs) are a cysteine-rich protein that scavenges reactive oxygen species. Hypoxia is involved in the prog...
The importance of daily life activities in managing obesity in patients with type 2 diabetes mellitus: a study using physical activity records
The importance of daily life activities in managing obesity in patients with type 2 diabetes mellitus: a study using physical activity records
Physical activity, including non-exercise activities, is important in the management of obesity in patients with type 2 di...
Differential association of hyperglucagonemia with C-peptide levels in diabetic ketosis/ketoacidosis and hyperosmolar hyperglycemic state
Differential association of hyperglucagonemia with C-peptide levels in diabetic ketosis/ketoacidosis and hyperosmolar hyperglycemic state
Glucagon plays a pivotal role in the development of hyperglycemia in diabetes mellitus. The purpose of this study was to i...
Glucagon suppression under GLP-1RA therapy: hidden trade-offs for muscle and resilience
Glucagon suppression under GLP-1RA therapy: hidden trade-offs for muscle and resilience
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have rapidly transformed the management of type 2 diabetes and obesit...
Time trends in the prescription of sodium-glucose co-transporter-2 inhibitors based on a claims database in Japan from 2014 to 2022: expanded use in older adults, those with comorbidities, and those potentially initiating diabetes treatment
Time trends in the prescription of sodium-glucose co-transporter-2 inhibitors based on a claims database in Japan from 2014 to 2022: expanded use in older adults, those with comorbidities, and those potentially initiating diabetes treatment
Sodium-glucose cotransporter-2 inhibitors (SGLT2Is) were initially prescribed with caution due to potential adverse effect...
Harnessing ROCK biology to revolutionize diabetic nephropathy: decoding mechanisms, designing therapies
Harnessing ROCK biology to revolutionize diabetic nephropathy: decoding mechanisms, designing therapies
Diabetes remains a major cause of kidney failure globally, presenting substantial challenges to healthcare systems worldwi...
Relationship between changes in uric acid levels and renal function during 12 months of treatment with luseogliflozin
Relationship between changes in uric acid levels and renal function during 12 months of treatment with luseogliflozin
Sodium-glucose cotransporter-2 (SGLT2) inhibitors can effectively improve blood glucose levels in patients with type 2 dia...
A case–control study on the prevalence of depression and its biomarkers in Type 2 diabetes mellitus patients
A case–control study on the prevalence of depression and its biomarkers in Type 2 diabetes mellitus patients
Type 2 diabetes mellitus (T2DM) is a common metabolic disease that impacts patients' physical and mental well-being an...
Association of serum levels of carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA) with diabetes mellitus (DM): a systematic review and meta-analysis
Association of serum levels of carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA) with diabetes mellitus (DM): a systematic review and meta-analysis
Type 2 diabetes mellitus (T2DM) affects 537 million people worldwide, with its prevalence and complications conti...
Berberine in diabetic nephropathy: mechanistic overview
Berberine in diabetic nephropathy: mechanistic overview
Diabetic nephropathy (DN) represents the most common cause of end-stage renal disease (ESRD) worldwide, affecting 20–...
Impact of a COVID-19 emergency declaration on blood glucose levels in individuals with type 1 diabetes treated with a sensor-augmented pump
Impact of a COVID-19 emergency declaration on blood glucose levels in individuals with type 1 diabetes treated with a sensor-augmented pump
COVID-19 emergency declarations and ensuing lockdowns affected lifestyle and glycemic control in individuals with diabetes...
Perception of hyper-/hypoglycemia and its related factors in type 2 diabetes: a continuous glucose monitoring-based prospective observational study
Perception of hyper-/hypoglycemia and its related factors in type 2 diabetes: a continuous glucose monitoring-based prospective observational study
Underestimating hyper-/hypoglycemia or failure to perceive hyperglycemia hinders optimal glucose management in diabetes ca...
Association of metformin administration with the serum levels of zinc and homocysteine in patients with type 2 diabetes: a cross-sectional study
Association of metformin administration with the serum levels of zinc and homocysteine in patients with type 2 diabetes: a cross-sectional study
Metformin treatment has a risk factor of reduced serum concentrations of vitamin B12 and zinc, indicating its association ...
Sitagliptin, diabetes mellitus, and heart failure: an in-depth review of sitagliptin therapy and heart failure in patients with diabetes mellitus
Sitagliptin, diabetes mellitus, and heart failure: an in-depth review of sitagliptin therapy and heart failure in patients with diabetes mellitus
Heart failure (HF) is characterized by impairments in cardiac function and heart structural changes. Type-2 diabetes melli...
Case-based learning: a case of maturity-onset diabetes of the young 5 (MODY5) due to 17q12 microdeletion with a diminished plasma glucagon level
Case-based learning: a case of maturity-onset diabetes of the young 5 (MODY5) due to 17q12 microdeletion with a diminished plasma glucagon level
Maturity-onset diabetes of the young type 5 (MODY5), causally associated with loss-of-function of the HNF1B gene, is a rar...
Association among the number of natural teeth, dental maintenance visits and diabetes status: a cross-sectional study using employment-based healthcare claims database
Association among the number of natural teeth, dental maintenance visits and diabetes status: a cross-sectional study using employment-based healthcare claims database
Although diabetes is associated with the risk of tooth loss, there are no large-scale studies examining the reality and th...
Minocycline reduces proinflammatory and oxidative stress markers in the spinal cord and morphology changes in sciatic nerve of Type 2 diabetic neuropathy rat model
Minocycline reduces proinflammatory and oxidative stress markers in the spinal cord and morphology changes in sciatic nerve of Type 2 diabetic neuropathy rat model
This study investigated the effects of minocycline on proinflammatory cytokines, oxidative stress marker levels in the spi...
Renal function trajectories of Japanese adults with diabetic kidney disease on different diet therapies including energy-restricted and low-carbohydrate diets: a retrospective cohort study
Renal function trajectories of Japanese adults with diabetic kidney disease on different diet therapies including energy-restricted and low-carbohydrate diets: a retrospective cohort study
Recently, the Japan Diabetes Society changed its nutrition recommendations and now recognizes a low-carbohydrate diet as a...
Improving postprandial hyperglycemia in prediabetic, sedentary office workers with immediately post-lunch, intermediate-intensity exercise: a comprehensive evaluation using a physical activity tracker, a dietary management application, and continuous glucose monitoring
Improving postprandial hyperglycemia in prediabetic, sedentary office workers with immediately post-lunch, intermediate-intensity exercise: a comprehensive evaluation using a physical activity tracker, a dietary management application, and continuous glucose monitoring
This study investigated if immediately post-lunch exercise may improve postprandial hyperglycemia in individuals with pred...
Optimal foot skin care for diabetes-related foot ulcer prevention: scoping review
Optimal foot skin care for diabetes-related foot ulcer prevention: scoping review
In patients with diabetes, autonomic neuropathy leads to reduced sweating, which can lead to dry skin, and if the conditio...
Periodontal disease and the incident risk of diabetes mellitus in Japanese men and women: a 12-year cohort study
Periodontal disease and the incident risk of diabetes mellitus in Japanese men and women: a 12-year cohort study
This study assessed the association between periodontal disease and the development of diabetes mellitus, as well as the e...
Longitudinal monitoring of urinary C-peptide levels following discontinuation of sacubitril/valsartan in a type 2 diabetes patient: a case report and literature review
Longitudinal monitoring of urinary C-peptide levels following discontinuation of sacubitril/valsartan in a type 2 diabetes patient: a case report and literature review
We report two cases of diabetes mellitus treated with sacubitril/valsartan, whose urinary C-peptide dynamics exhibited sig...
Mechanisms of angiotensin II to induce depression in diabetes
Mechanisms of angiotensin II to induce depression in diabetes
The expression of angiotensin II (Ang II) has been reported in diabetes associated with hypertension and inflammatory proc...
CIDEC is most closely associated with fat storage in human adipose tissue among CIDE family isoforms in severely obese subjects: a cross-sectional study
CIDEC is most closely associated with fat storage in human adipose tissue among CIDE family isoforms in severely obese subjects: a cross-sectional study
The cell death–inducing DFF45-like effector (CIDE) family comprises CIDEA, CIDEB, and CIDEC (fat-specific protein of...
Efficacy of carbohydrate counting in people with type 1 and type 2 diabetes mellitus: a systematic review and meta-analysis
Efficacy of carbohydrate counting in people with type 1 and type 2 diabetes mellitus: a systematic review and meta-analysis
Although carbohydrate counting (CC) being the recommended dietary strategy for achieving glycemic control in people with d...
Rapid improvement of severe fatty liver in a case of fulminant type 1 diabetes following insulin treatment
Rapid improvement of severe fatty liver in a case of fulminant type 1 diabetes following insulin treatment
A 36-year-old woman presented to the emergency room with a consciousness disorder after developing abdominal pain with dia...
Influence of diet and body weight in treatment-resistant acquired partial lipodystrophy after hematopoietic stem cell transplantation and its potential for metabolic improvement
Influence of diet and body weight in treatment-resistant acquired partial lipodystrophy after hematopoietic stem cell transplantation and its potential for metabolic improvement
Lipodystrophy is a rare disease characterized by various metabolic complications resulting from the complete or partial lo...
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