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Vitamin D in Gut and Systemic Immune Tolerance and in Infections’ Risk: An International Evidence-Based Consensus Statement
Vitamin D in Gut and Systemic Immune Tolerance and in Infections’ Risk: An International Evidence-Based Consensus Statement
Vitamin D, classically linked to calcium-phosphate metabolism and skeletal health, is increasingly recognized as a pleiotr...
Neurocognitive performance and appetite-regulating hormones in obesity with and without eating disorders: A comprehensive review and empirical analysis
Neurocognitive performance and appetite-regulating hormones in obesity with and without eating disorders: A comprehensive review and empirical analysis
Obesity and eating disorders (ED) share neurocognitive vulnerabilities involving executive control and reward processing, ...
Algorithm-guided insulin therapy in hospitalized patients: current evidence, implementation challenges, and future perspectives
Algorithm-guided insulin therapy in hospitalized patients: current evidence, implementation challenges, and future perspectives
Up to 40% of hospitalized patients experience hyperglycemia, often caused by undiagnosed diabetes or stress-induced hyperg...
Hypothalamus-liver talks: whispers in the language of metabolism
Hypothalamus-liver talks: whispers in the language of metabolism
Closely associated with the exponential increase of obesity and sedentary life, liver-related disorders are a major global...
Targeting the activin/myostatin - actrii pathway to preserve skeletal muscle mass in obesity: mechanistic insights and therapeutic perspectives
Targeting the activin/myostatin - actrii pathway to preserve skeletal muscle mass in obesity: mechanistic insights and therapeutic perspectives
Skeletal muscle deterioration is a relevant complication of obesity associated with poor physical function, impairment of ...
The suprachiasmatic nucleus: a central pacemaker for temporal coordination of energy metabolic homeostasis
The suprachiasmatic nucleus: a central pacemaker for temporal coordination of energy metabolic homeostasis
The suprachiasmatic nucleus (SCN) is the principal light-entrained circadian pacemaker in mammals, coordinating daily rhyt...
Therapy for aggressive pituitary tumors and carcinomas
Therapy for aggressive pituitary tumors and carcinomas
The management of aggressive pituitary tumors and carcinomas remains challenging. This review article discusses available ...
From diet to hypothalamic dysfunction: Neuroanatomical and hormonal integration of the microbiota-hypothalamus-adipose tissue axis
From diet to hypothalamic dysfunction: Neuroanatomical and hormonal integration of the microbiota-hypothalamus-adipose tissue axis
Obesity is a chronic neurometabolic disorder characterized by low-grade systemic inflammation, adipose tissue dysfunction,...
From brain bioenergetics to hypothalamic glucoregulation: A shared-systems hypothesis for intrinsic dysglycemia in schizophrenia
From brain bioenergetics to hypothalamic glucoregulation: A shared-systems hypothesis for intrinsic dysglycemia in schizophrenia
Dysglycemia and type 2 diabetes occur at markedly elevated rates in people with schizophrenia-spectrum disorders, contribu...
Balancing acts: lateral hypothalamic circuits coordinating feeding, anxiety, and social interactions
Balancing acts: lateral hypothalamic circuits coordinating feeding, anxiety, and social interactions
Survival requires organisms to continuously balance competing motivational drives, including the need to acquire energy, a...
Distractor effect of food stimuli among patients with binge eating behaviour - a narrative review and pilot data
Distractor effect of food stimuli among patients with binge eating behaviour - a narrative review and pilot data
The distractor effect refers to performance impairments caused by task-irrelevant stimuli capturing attention and disrupt ...
Can breastfeeding practices explain sociodemographic disparities in childhood obesity and healthy eating? Results from NHANES 2005–2018
Can breastfeeding practices explain sociodemographic disparities in childhood obesity and healthy eating? Results from NHANES 2005–2018
This study aims to review and analyze the relationship between early childhood breastfeeding, nutrition, and weight status...
Beyond weight loss: Integrating GLP-1 RA therapies into psychological and behavioral care for obesity and binge eating disorder
Beyond weight loss: Integrating GLP-1 RA therapies into psychological and behavioral care for obesity and binge eating disorder
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) represent a major advancement in obesity treatment, offering robust ...
Harnessing food cue evoked neuroimaging towards treatment optimisation for obesity and binge eating disorder
Harnessing food cue evoked neuroimaging towards treatment optimisation for obesity and binge eating disorder
Obesity and binge eating disorder (BED) are global health concerns that share overlapping neural mechanisms. These include...
Shared Brain factors in eating disorders and obesity: a systematic review of functional near-infrared spectroscopy (fNIRS) studies
Shared Brain factors in eating disorders and obesity: a systematic review of functional near-infrared spectroscopy (fNIRS) studies
Eating disorders (EDs) and obesity have traditionally been conceptualized as distinct entities, yet accumulating evidence ...
Diabetes and cancer: glucose control impact on survival and tumor outcomes
Diabetes and cancer: glucose control impact on survival and tumor outcomes
Diabetes mellitus (DM) and cancer are major global health challenges that increasingly coexist due to shared risk factors ...
Overcoming the barriers in the screening, diagnosis, and follow-up of patients with metabolic dysfunction–associated steatotic liver disease (MASLD) and metabolic dysfunction–associated steatohepatitis (MASH)
Overcoming the barriers in the screening, diagnosis, and follow-up of patients with metabolic dysfunction–associated steatotic liver disease (MASLD) and metabolic dysfunction–associated steatohepatitis (MASH)
In 2024, a comprehensive framework for the screening, diagnosis, and management of metabolic dysfunction–associated ...
Interaction of physical activity and gut-brain axis: relevance for obesity
Interaction of physical activity and gut-brain axis: relevance for obesity
The gut–brain axis represents a bidirectional communication system disrupted in obesity. Evidence suggests associati...
Pregnancy-associated thyroid disorders: the role of genetic, epigenetic, and oxidative stress factors
Pregnancy-associated thyroid disorders: the role of genetic, epigenetic, and oxidative stress factors
Thyroid inflammation during pregnancy, particularly Hashimoto’s thyroiditis (HT) and postpartum thyroiditis (PPT), h...
Mechanisms of exercise in preventing cardiovascular diseases: Insights from gut microbiota characteristics in pathological states of cardiovascular diseases
Mechanisms of exercise in preventing cardiovascular diseases: Insights from gut microbiota characteristics in pathological states of cardiovascular diseases
Cardiovascular diseases (CVD) are major lethal diseases worldwide. Imbalance of gut microbiota (GM) homeostasis affects th...
Pathophysiological insights into asprosin: an emerging adipokine in reproductive health
Pathophysiological insights into asprosin: an emerging adipokine in reproductive health
Asprosin is a versatile protein hormone primarily produced by white adipose tissue (WAT). When secreted into the bloodstre...
Lights or shadows, a promising future for positron emission tomography in pituitary tumors: a systematic review
Lights or shadows, a promising future for positron emission tomography in pituitary tumors: a systematic review
The diagnosis of pituitary adenomas (PAs), also called pituitary tumors or neuroendocrine tumors (PitNETs) currently invol...
Exploring obesity phenotypes: a longitudinal perspective
Exploring obesity phenotypes: a longitudinal perspective
Traditional reliance on Body Mass Index (BMI) as a diagnostic tool for obesity is increasingly challenged due to its inabi...
Association between continuous glucose monitoring metrics and cardiovascular autonomic neuropathy in diabetic patients: a systematic review
Association between continuous glucose monitoring metrics and cardiovascular autonomic neuropathy in diabetic patients: a systematic review
Cardiovascular autonomic neuropathy (CAN) is a serious and prevalent complication of diabetes, linked to significant morbi...
Neurovascular plasticity as a modulator of hypothalamic function
Neurovascular plasticity as a modulator of hypothalamic function
The hypothalamus, located at the most ventral part of the brain, is the central regulator of homeostatic processes such as...
Sexual dimorphism in the development and function of the melanocortin system
Sexual dimorphism in the development and function of the melanocortin system
The melanocortin system is fundamental for the regulation of whole-body energy homeostasis. This system consists of pro-op...
BBSome: An essential component of hypothalamic regulation of energy homeostasis
BBSome: An essential component of hypothalamic regulation of energy homeostasis
The BBSome is a protein complex composed of eight Bardet-Biedl syndrome (BBS) proteins. Although the BBSome is best known ...
Targeted therapeutic strategies as alternative and sustainable treatment options for obesity-induced steatohepatitis
Targeted therapeutic strategies as alternative and sustainable treatment options for obesity-induced steatohepatitis
The development of metabolic dysfunction-associated steatotic liver disease (MASLD), and its progression to metabolic dysf...
Hyperphagia in rare melanocortin-4 receptor pathway diseases: therapeutic options and assessing treatment response
Hyperphagia in rare melanocortin-4 receptor pathway diseases: therapeutic options and assessing treatment response
Hyperphagia is a hallmark of both congenital and acquired rare melanocortin-4 receptor (MC4R) pathway diseases. Currently,...
Body mass index and body composition changes in transgender people undergoing gender-affirming hormone therapy: a systematic review and meta-analysis
Body mass index and body composition changes in transgender people undergoing gender-affirming hormone therapy: a systematic review and meta-analysis
Gender-affirming hormone therapy (GAHT) uses sex steroid hormones to induce desired physical changes, improving the qualit...
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