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Dynamic modulation of LH secretion by continuous kisspeptin infusion in healthy men
Dynamic modulation of LH secretion by continuous kisspeptin infusion in healthy men
Kisspeptin stimulates gonadotropin-releasing hormone (GnRH) release and, by extension, gonadotropin secretion. Although co...
Genetic background of obesity: a case-control study
Genetic background of obesity: a case-control study
The rising prevalence of obesity and type 2 diabetes mellitus (T2DM) constitutes a major global public health concern. Inc...
Associations between multiple metabolic indices and circadian syndrome: a cross-sectional study with mediation analysis of the C-reactive protein triglyceride glucose index
Associations between multiple metabolic indices and circadian syndrome: a cross-sectional study with mediation analysis of the C-reactive protein triglyceride glucose index
The aim of this study is to comprehensively investigate the independent associations between a wide array of novel metabol...
Effects of melatonin on muscle and liver bioenergetic profiles: focus on acylcarnitines following endurance swimming exercise in rats
Effects of melatonin on muscle and liver bioenergetic profiles: focus on acylcarnitines following endurance swimming exercise in rats
Melatonin (N-acetyl-5-methoxytryptamine) plays a key role in lipid metabolism regulation, directly influencing fatty acid ...
Prognostic factors for cardiovascular complications induced by catecholamines in pheochromocytomas and paragangliomas: a systematic review and meta-analysis
Prognostic factors for cardiovascular complications induced by catecholamines in pheochromocytomas and paragangliomas: a systematic review and meta-analysis
Pheochromocytomas and paragangliomas (PPGLs) can trigger major cardiovascular events (MACEs) due to unpredictable release ...
Advances in diabetes technology: clinical implications, limitations, and future perspectives
Advances in diabetes technology: clinical implications, limitations, and future perspectives
Diabetes technology has transformed substantially over the past two decades, becoming central to modern diabetes managemen...
Global trends in the prevalence of type 2 diabetes mellitus: understanding trajectories through conceptual frameworks
Global trends in the prevalence of type 2 diabetes mellitus: understanding trajectories through conceptual frameworks
Type 2 diabetes mellitus (T2DM) is imposing a substantial and rapidly growing global health burden. Disease estimates vary...
Association between serum vitamins and sex hormone levels in adolescent males: based on the National Health and Nutrition Examination Survey (NHANES)
Association between serum vitamins and sex hormone levels in adolescent males: based on the National Health and Nutrition Examination Survey (NHANES)
The association between serum vitamins and sex hormones has gained considerable research interest; however, studies focusi...
Non-invasive imaging diagnostic techniques in metabolic dysfunction-associated steatotic liver disease: a roadmap for clinicians
Non-invasive imaging diagnostic techniques in metabolic dysfunction-associated steatotic liver disease: a roadmap for clinicians
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed nonalcoholic fatty liver disease (NAFL...
Papillary thyroid carcinoma discovered in a patient on semaglutide therapy for metabolic syndrome: a case presentation and review of current evidence
Papillary thyroid carcinoma discovered in a patient on semaglutide therapy for metabolic syndrome: a case presentation and review of current evidence
Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1 RA), is widely used for the management of type 2 diabetes, ...
Highly selective SGLT2 inhibitors suppress glucose uptake in alpha-TC1 cells, while glucagon secretion is not affected
Highly selective SGLT2 inhibitors suppress glucose uptake in alpha-TC1 cells, while glucagon secretion is not affected
The existence of sodium-glucose cotransporter 2 (SGLT2) in pancreatic alpha cells and its potential roles in glucagon secr...
Efficacy of bariatric techniques in the management of pediatric and adolescent obesity: a systematic review
Efficacy of bariatric techniques in the management of pediatric and adolescent obesity: a systematic review
Pediatric-adolescent obesity is a serious, multifactorial-multisystem disease associated with severe comorbidities. Surgic...
PRKAR1A-related acrodysostosis with partial growth hormone deficiency: 18-month response to recombinant human growth hormone
PRKAR1A-related acrodysostosis with partial growth hormone deficiency: 18-month response to recombinant human growth hormone
To describe the 18-month auxological response to recombinant human growth hormone (rhGH) therapy in a pediatric patient wi...
Lipidomics and proteomics in MASLD: reading the molecular script toward precision therapeutics
Lipidomics and proteomics in MASLD: reading the molecular script toward precision therapeutics
Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognized as a multisystem disorder char...
A novel homozygous thyroglobulin gene variant presenting with massive congenital goiter and neonatal airway obstruction
A novel homozygous thyroglobulin gene variant presenting with massive congenital goiter and neonatal airway obstruction
Congenital hypothyroidism due to thyroid dyshormonogenesis is a rare inherited disorder that may present with goiter of va...
Efficacy and safety of osilodrostat in patients with ectopic Cushing’s syndrome
Efficacy and safety of osilodrostat in patients with ectopic Cushing’s syndrome
To analyze the efficacy and safety of osilodrostat in patients with ectopic Cushing’s syndrome (ECS) in real-world s...
EndoBridge 2025: pearls and highlights
EndoBridge 2025: pearls and highlights
The 13th Annual EndoBridge Meeting took place in Antalya, Türkiye, from October 23 to 26, 2025. Accredited by the Eur...
Genetic risk factors for diabetic retinopathy in the Greek population: a review of key gene polymorphisms
Genetic risk factors for diabetic retinopathy in the Greek population: a review of key gene polymorphisms
Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus and a leading cause o...
Triage for night eating syndrome (NES) in pregnant women: a cross-sectional pilot study
Triage for night eating syndrome (NES) in pregnant women: a cross-sectional pilot study
To estimate the prevalence of pregnant women screened positive for night eating syndrome (NES) (also known as night, night...
Association between ethylene oxide exposure and serum sex hormone in adult males: the mediating role of serum albumin
Association between ethylene oxide exposure and serum sex hormone in adult males: the mediating role of serum albumin
Ethylene oxide (EO) is an organic compound with carcinogenic toxicity. However, no relevant studies have explored the asso...
Effects of hawthorn vinegar on high-fat diet-induced metabolic changes in obese rat model
Effects of hawthorn vinegar on high-fat diet-induced metabolic changes in obese rat model
Obesity is a significant health problem with rising incidence globally. Consuming diets or foods with bioactive nutrients ...
Lanreotide in endothelial corneal inflammation
Lanreotide in endothelial corneal inflammation
Ethical approval No human participants and/or animals were involved...
What ultimately underlies vitamin B12 and folate deficiency in subjects treated with biguanides?
What ultimately underlies vitamin B12 and folate deficiency in subjects treated with biguanides?
Metformin, the main biguanide in clinical settings, is the most common antidiabetic agent worldwide and has for years been...
Presentation of a missense variant in a Greek patient with pheochromocytoma
Presentation of a missense variant in a Greek patient with pheochromocytoma
Approximately 40% of pheochromocytomas and paragangliomas (PPGLs) are caused by germline mutations. MDH2 encodes the mitoc...
Immune checkpoint inhibitors and metabolic events: results from a European safety analysis
Immune checkpoint inhibitors and metabolic events: results from a European safety analysis
Immune checkpoint inhibitors (ICIs) include programmed death-1 receptor (PD1) inhibitors, programmed death-ligand 1 (PDL1)...
Hand pathology in type 1 diabetes mellitus: a case-control study
Hand pathology in type 1 diabetes mellitus: a case-control study
This study aims to investigate the factors associated with diabetic hand (DH) in patients with type 1 diabetes mellitus (T...
Catecholaminergic activity among young adults after high phosphorus intake during childhood and adolescence
Catecholaminergic activity among young adults after high phosphorus intake during childhood and adolescence
Elevated catecholamine secretion has been reported after high dietary phosphate intake in experimental studies in animals ...
Sex-dependent PRRT toxicity in patients with metastatic somatostatin receptor-avid neuroendocrine tumors treated with Lu-DOTATATE
Sex-dependent PRRT toxicity in patients with metastatic somatostatin receptor-avid neuroendocrine tumors treated with Lu-DOTATATE
To assess risk factors for peptide receptor radionuclide therapy (PRRT)-related toxicity to the kidneys, liver, and bone m...
Involvement of C-peptide in the progression of type 2 diabetes mellitus through triglyceride-centered lipid metabolism
Involvement of C-peptide in the progression of type 2 diabetes mellitus through triglyceride-centered lipid metabolism
Fasting C-peptide (FCP), which is co-secreted with insulin, plays a critical role in the pathogenesis of diabetic complica...
New insights into sexual dimorphism in cardiometabolic health
New insights into sexual dimorphism in cardiometabolic health
Sexual dimorphism is evident in several key metabolic processes, extending to the pathophysiology, incidence, and progress...
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