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PPAR-γ dysregulation links NF-κB activation and Nrf2-driven antioxidant responses in axial spondyloarthritis: A pilot study
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Chronic kidney disease trajectories in lupus nephritis: Is progression unavoidable?
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Endothelial cell-derived plasminogen activator inhibitor-1 potentiates thrombosis in antiphospholipid syndrome
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Mechanistic studies on the regulation of systemic sclerosis progression by imbalance in angiogenic T cell subsets
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Runx3 instructs Aire+ mTEC development, TSA gene expression, and central tolerance
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Orelabrutinib for systemic lupus erythematosus: A randomised, double-blind, placebo-controlled study
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Systemic sclerosis and female reproductive health over lifespan: A systematic review and meta-analysis
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PAD2-mediated citrullination of MBP and early myelin destabilization in multiple sclerosis
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Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in mice
Rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) are chronic inflammatory systemic autoimmune diseases th...
FAPI PET/CT for tracking disease trajectory in myositis-related interstitial lung disease
BackgroundInterstitial lung disease (ILD) is associated with morbidity and mortality in idiopathic inflammatory myopathies...
Transcriptomics of autoimmune diseases identifies FGFR1 as a target for pancreatic β-cell protection
Autoimmune diseases, including type 1 diabetes (T1D), rheumatoid arthritis (RA), multiple sclerosis (MS) and Hashimoto's d...
Immunological and fibrotic profiling in the NOD.c3c4 murine model of autoimmune cholangitis
Primary Biliary Cholangitis (PBC) is a chronic autoimmune liver disease characterized by the presence of anti-mitochondria...
Epigenetic differences at immune and type 1 diabetes susceptibility genes in blood from young children after COVID-19 infection
Volume 156, September 2025, 103468Author links open overlay panel, , , , , , , , , , , Highlights•COVID-19 infection assoc...
Altered glucose metabolism in B cells: Implications for the pathogenesis and treatment of autoimmune diseases
Autoimmune diseases occur when the immune system malfunctions, failing to recognize the body's own tissues or organs and s...
Targeted protein degradation in autoimmune diseases: from mechanisms to therapeutic breakthroughs
Autoimmune diseases pose significant challenges due to the high risks associated with abnormal immune responses to self-an...
Lymphoma driver mutations at the root of somatic evolution of nerve-damaging autoantibodies in myelin associated glycoprotein neuropathy
BackgroundIn autoimmune disease it is not understood how self-reactive B cells escape immune tolerance checkpoints to prod...
Methotrexate and low-dose prednisone in idiopathic retroperitoneal fibrosis: a randomised clinical trial
ObjectivesTo test the efficacy and safety of methotrexate plus low-dose prednisone in patients with idiopathic retroperito...
Evaluation of the mycophenolate mofetil–rituximab combination in systemic sclerosis: a French retrospective multicenter study (MycRiSSc)
ObjectivesMycophenolate mofetil (MMF) and rituximab (RTX) are recommended as first-line therapies for skin and interstitia...
Calprotectin and neurofilament serum levels correlate with treatment response in myasthenia gravis under intensified therapy–A pilot study
ObjectiveNew therapeutic options have recently emerged for patients with highly active, acetylcholine receptor antibody–po...
Treatment outcomes stratified by interferon profile and autoantibodies in rheumatoid arthritis
Rheumatoid arthritis (RA) is one of the most prevalent chronic inflammatory diseases that primarily affects the joints; ho...
The double-edged sword role of copper in rheumatoid arthritis: Mechanisms, therapeutics, and challenges
RA is a chronic, inflammatory, autoimmune disease with an unclear etiology, primarily manifested by inflammation, deformit...