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Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in mice
Rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) are chronic inflammatory systemic autoimmune diseases th...
FAPI PET/CT for tracking disease trajectory in myositis-related interstitial lung disease
BackgroundInterstitial lung disease (ILD) is associated with morbidity and mortality in idiopathic inflammatory myopathies...
Transcriptomics of autoimmune diseases identifies FGFR1 as a target for pancreatic β-cell protection
Autoimmune diseases, including type 1 diabetes (T1D), rheumatoid arthritis (RA), multiple sclerosis (MS) and Hashimoto's d...
Immunological and fibrotic profiling in the NOD.c3c4 murine model of autoimmune cholangitis
Primary Biliary Cholangitis (PBC) is a chronic autoimmune liver disease characterized by the presence of anti-mitochondria...
Epigenetic differences at immune and type 1 diabetes susceptibility genes in blood from young children after COVID-19 infection
Volume 156, September 2025, 103468Author links open overlay panel, , , , , , , , , , , Highlights•COVID-19 infection assoc...
Altered glucose metabolism in B cells: Implications for the pathogenesis and treatment of autoimmune diseases
Autoimmune diseases occur when the immune system malfunctions, failing to recognize the body's own tissues or organs and s...
Targeted protein degradation in autoimmune diseases: from mechanisms to therapeutic breakthroughs
Autoimmune diseases pose significant challenges due to the high risks associated with abnormal immune responses to self-an...
Corrigendum to “Anti-DNA antibody-targeted D-peptide nanoparticles ameliorate lupus nephritis in MRL/lpr mice” [J. Autoimmun. 145 (2024) 103205]
Volume 156, September 2025, 103470Author links open overlay panelYaqi Wang a, Shuang Wang a, Wei Liu a, Hanjiang Gu a, Mai...
Lymphoma driver mutations at the root of somatic evolution of nerve-damaging autoantibodies in myelin associated glycoprotein neuropathy
BackgroundIn autoimmune disease it is not understood how self-reactive B cells escape immune tolerance checkpoints to prod...
Methotrexate and low-dose prednisone in idiopathic retroperitoneal fibrosis: a randomised clinical trial
ObjectivesTo test the efficacy and safety of methotrexate plus low-dose prednisone in patients with idiopathic retroperito...
Preliminary safety and efficacy of relmacabtagene autoleucel (relma-cel) in adults with moderately to severely active systemic lupus erythematosus: a phase I dose-escalation study
BackgroundChimeric antigen receptor (CAR)-T cell therapy has emerged as a transformative treatment in autoimmune diseases....
Interpretation of the association between thyroid peroxidase antibodies and thyroid function during pregnancy: An individual participant data meta-analysis
BackgroundThyroid peroxidase antibody (TPOAb) positivity is the most important risk factor for hypothyroidism and determin...
Evaluation of the mycophenolate mofetil–rituximab combination in systemic sclerosis: a French retrospective multicenter study (MycRiSSc)
ObjectivesMycophenolate mofetil (MMF) and rituximab (RTX) are recommended as first-line therapies for skin and interstitia...
Comparative risk of rheumatoid arthritis between glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors in type 2 diabetes
Rheumatoid arthritis (RA) is the most prevalent chronic inflammatory disease, characterized by persistent inflammation of ...
Calprotectin and neurofilament serum levels correlate with treatment response in myasthenia gravis under intensified therapy–A pilot study
ObjectiveNew therapeutic options have recently emerged for patients with highly active, acetylcholine receptor antibody–po...
Treatment outcomes stratified by interferon profile and autoantibodies in rheumatoid arthritis
Rheumatoid arthritis (RA) is one of the most prevalent chronic inflammatory diseases that primarily affects the joints; ho...
The double-edged sword role of copper in rheumatoid arthritis: Mechanisms, therapeutics, and challenges
RA is a chronic, inflammatory, autoimmune disease with an unclear etiology, primarily manifested by inflammation, deformit...
Mitochondrial dysfunction is a potential key mechanism for atherosclerosis predisposition in patients with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a complex autoimmune disease influenced by genetic, environmental, and immunological...
The concept of severity in psoriatic arthritis: a scoping review of the literature
Psoriatic arthritis (PsA) is a chronic, inflammatory and complex disease characterized by skin and joint involvement, freq...
Chimeric antigen receptor T cell therapy: a new frontier therapeutic landscape in autoimmune diseases
Chimeric antigen receptor-T (CAR-T) cell therapy is a genetically engineered approach that introduces synthetic receptor m...
CAR-T cell targeting three receptors on autoreactive B cells for systemic lupus erythematosus therapy
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Associations between domestic hard water exposure and incident psoriasis in adults: Insights from the UK Biobank cohort study
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Pulmonary and serum cytokine profiles of patients with anti-ARS and anti-MDA5 antibodies
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Primary Cesarean delivery and future risk of maternal autoimmune disease: A population-based cohort study
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Identification of clonally expanded T-cell receptor sequences in giant cell arteritis
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Familial patterns of alopecia areata: A systematic review and meta-analysis
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Anti-retinal immune response in sarcoid uveitis: A potential role for PCLO as an antigenic target
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Diversity and function of regulatory T cells in health and autoimmune diseases
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Glycobiology of psoriasis: A review
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The impact of gut microbiome on immune and metabolic homeostasis in type 1 diabetes: Clinical insights for prevention and treatment strategies
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