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Optimizing 2D in vitro differentiation conditions for C2C12 murine myoblasts on gelatin hydrogel
Optimizing 2D in vitro differentiation conditions for C2C12 murine myoblasts on gelatin hydrogel
Optimizing in vitro differentiation protocols for skeletal muscle cells is essential for producing mature, functional myot...
Polystyrene microplastics (PS-MPs) disturb skeleto-muscular energy metabolism and tissue architecture following sub-acute exposure: A dose-responsive study
Polystyrene microplastics (PS-MPs) disturb skeleto-muscular energy metabolism and tissue architecture following sub-acute exposure: A dose-responsive study
Polystyrene microplastic (PS-MP), known as a white pollutant, exhibited adverse effects on aquatic and terrestrial animals...
Direct measurement of mavacamten and deoxyATP perturbation of the SRX/DRX ratio in porcine cardiac myofibrils using a simple, accessible and multiplexed approach
Direct measurement of mavacamten and deoxyATP perturbation of the SRX/DRX ratio in porcine cardiac myofibrils using a simple, accessible and multiplexed approach
Cardiac muscle adapts to varying physiological demands by modulating the number of active myosin II motors available for c...
Myostatin deficiency blunts mechanical adaptation of soleus muscle to overload
Myostatin deficiency blunts mechanical adaptation of soleus muscle to overload
The aim of this study was to determine the impact of myostatin deficiency on the mechanical and contractile adaptations of...
Corilagin inhibits the proliferation of vascular smooth muscle and excessive matrix deposition following vascular injury via the MAPK pathway
Corilagin inhibits the proliferation of vascular smooth muscle and excessive matrix deposition following vascular injury via the MAPK pathway
Corilagin is a type of ellagitannin that exhibits inhibitory effects on the proliferation of vascular smooth muscle cells ...
Tubastatin A attenuates impaired autophagic degradation and promotes myogenic program in skeletal muscle following downhill running
Tubastatin A attenuates impaired autophagic degradation and promotes myogenic program in skeletal muscle following downhill running
Microtubule acetylation is known to promote autophagic degradation; however, its therapeutic potential in resolving exerci...
The use of acoustic myography to assess changes in muscle control with ageing in healthy subjects ranging 20 to 79 years
The use of acoustic myography to assess changes in muscle control with ageing in healthy subjects ranging 20 to 79 years
This study has used acoustic myography as a technique to assess not only the number of active fibres and their firing freq...
A single S-ketamine injection enhances mTOR signaling in rat skeletal muscle
A single S-ketamine injection enhances mTOR signaling in rat skeletal muscle
S-ketamine is recognized as a rapid-acting antidepressant, exerting its effects primarily through activation of the mTOR s...
CD36 regulates myogenic differentiation via chronic integrated stress response – implications for muscle aging
CD36 regulates myogenic differentiation via chronic integrated stress response – implications for muscle aging
The integrated stress response (ISR) and mitochondrial unfolded protein response (UPRmt) plays a vital role in myogenic di...
Short-duration electrical pulse stimulation induces myokines and mitochondrial adaptations in C2C12 myotubes
Short-duration electrical pulse stimulation induces myokines and mitochondrial adaptations in C2C12 myotubes
Physical activity induces rapid myokine and metabolic responses in skeletal muscle, yet the immediate cellular adaptations...
Methodological framing in muscle morphology and mechanics: aligning experimental protocols with scientific questions
Methodological framing in muscle morphology and mechanics: aligning experimental protocols with scientific questions
Askew GN, Marsh RL (1997) The effects of length trajectory on the mechanical power output of mouse skeletal muscles. J Exp...
The effect of nimesulide on skeletal muscle hypertrophy and load progression after 8 weeks of resistance training in wistar rats
The effect of nimesulide on skeletal muscle hypertrophy and load progression after 8 weeks of resistance training in wistar rats
Resistance training is currently a widely targeted practice due to its ability to induce vital adaptations resulting from ...
Stair-climbing resistance exercise, with or without oral turmeric ( L.) supplementation, relieves symptoms and promotes musculoskeletal repair in experimental rheumatoid arthritis in rats
Stair-climbing resistance exercise, with or without oral turmeric ( L.) supplementation, relieves symptoms and promotes musculoskeletal repair in experimental rheumatoid arthritis in rats
Rheumatoid arthritis is a chronic systemic inflammatory disease associated with joint inflammation, skeletal muscle dysfun...
Resistance-based exercise restores muscle health in dialysis patients
Resistance-based exercise restores muscle health in dialysis patients
Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are serious health concerns worldwide that require regular...
High-intensity interval training alleviates COPD-induced gastrocnemius muscle dysfunction via the BRD4/PGC-1α axis through restoring mitochondrial function and oxidative fiber composition
High-intensity interval training alleviates COPD-induced gastrocnemius muscle dysfunction via the BRD4/PGC-1α axis through restoring mitochondrial function and oxidative fiber composition
Skeletal muscle dysfunction (SMD) associated with Chronic obstructive pulmonary disease (COPD), characterized by muscle at...
Amiodarone disrupts thyroid hormone homeostasis and impairs myogenic progression and locomotor function in zebrafish embryos
Amiodarone disrupts thyroid hormone homeostasis and impairs myogenic progression and locomotor function in zebrafish embryos
Thyroid hormones (THs) are critical regulators of vertebrate embryonic development, governing cell proliferation, lineage ...
Effects of culture media glucose concentration on LHCN-M2 skeletal muscle cell viability, differentiation and metabolic phenotype: a proof-of-concept study
Effects of culture media glucose concentration on LHCN-M2 skeletal muscle cell viability, differentiation and metabolic phenotype: a proof-of-concept study
In vitro skeletal muscle culture models provide important insight into the cellular mechanisms which underpin skeletal mus...
The role of MEGF10 in myoblast fusion and hypertrophic response to overload of skeletal muscle
The role of MEGF10 in myoblast fusion and hypertrophic response to overload of skeletal muscle
Biallelic mutations in multiple EGF domain protein 10 (MEGF10) gene cause EMARDD (early myopathy, areflexia, respiratory d...
Differential impact of substrates on myosin heavy and light chain expression in human stem cell-derived cardiomyocytes at single-cell level
Differential impact of substrates on myosin heavy and light chain expression in human stem cell-derived cardiomyocytes at single-cell level
To fully exploit the potential of human pluripotent stem cell-derived cardiomyocytes, ideally they should acquire a mature...
Fluorescence lifetime imaging microscopy of endogenous fluorophores in health and disease
Fluorescence lifetime imaging microscopy of endogenous fluorophores in health and disease
Fluorescence Lifetime Imaging Microscopy (FLIM) of endogenous fluorophores has recently emerged as a powerful, marker-free...
Plasticity in leukocyte migration during haematopoiesis and inflammation
Plasticity in leukocyte migration during haematopoiesis and inflammation
Under normal physiological conditions, leukocytes and other tissue resident immune cells have been shown to migrate using ...
The influences of ARHGEF9 on myoblasts migration and differentiation
The influences of ARHGEF9 on myoblasts migration and differentiation
Rho guanine nucleotide exchange factor 9 (ARHGEF9), as a protein that assists small GTPases, is widely present in various ...
miR-2400 promotes proliferation of bovine skeletal muscle-derived satellite cells by regulating MAGED1 genes expression
miR-2400 promotes proliferation of bovine skeletal muscle-derived satellite cells by regulating MAGED1 genes expression
microRNAs play a crucial role in the intricate process of muscle satellite cells proliferation and differentiation. Previo...
Insights into human muscle biology from human primary skeletal muscle cell culture
Insights into human muscle biology from human primary skeletal muscle cell culture
This review arises from the symposium held in honour of Prof Jenny Morgan at UCL in 2024 and the authors would like to ack...
The elementary step that generates force and sinusoidal analysis in striated muscle fibers
The elementary step that generates force and sinusoidal analysis in striated muscle fibers
The elementary step that generates force by cross-bridges (CBs) in striated muscles is reviewed. A literature search focus...
The impact of mitokine MOTS-c administration on the soleus muscle of rats subjected to a 7-day hindlimb suspension
The impact of mitokine MOTS-c administration on the soleus muscle of rats subjected to a 7-day hindlimb suspension
The aim of the study was to investigate the effect of MOTS-c on the key functional alterations in the rat soleus muscle du...
Theoretical treatment of tension transients in muscle following sudden changes in orthophosphate concentration: implications for energy transduction
Theoretical treatment of tension transients in muscle following sudden changes in orthophosphate concentration: implications for energy transduction
The relative timing of the force-generating power stroke and release of the ATP-hydrolysis product orthophosphate (Pi) in ...
Influence of neuromuscular transmission and Na channel inhibitors on strength-duration relationship in isolated slow- and fast-twitch muscles
Influence of neuromuscular transmission and Na channel inhibitors on strength-duration relationship in isolated slow- and fast-twitch muscles
Strength-duration (S-D) relationship reflects muscle excitability which partially determines force production. Isolated mu...
Regulation and function of Pax3 in muscle stem cell heterogeneity and stress response
Regulation and function of Pax3 in muscle stem cell heterogeneity and stress response
Pax3 is a key transcription factor that regulates skeletal muscle development and regeneration and plays a critical role i...
Smooth muscle cells from skin perforator vessels as a new tool for vascular research
Smooth muscle cells from skin perforator vessels as a new tool for vascular research
Vascular smooth muscle cells (SMC) comprise the medial layer of blood vessels and are responsible for maintaining vascular...
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