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Development of metabolic syndrome by increasingly fructose-enriched water in Wistar rats
Development of metabolic syndrome by increasingly fructose-enriched water in Wistar rats
Several studies have shown that excessive fructose consumption increases the risk of developing metabolic syndrome (MS), w...
polysaccharides alleviate atopic dermatitis in vivo and in vitro through inhibition of inflammation and mitochondrial dysfunction
polysaccharides alleviate atopic dermatitis in vivo and in vitro through inhibition of inflammation and mitochondrial dysfunction
Atopic dermatitis (AD) is a chronic inflammatory skin disorder marked by immune dysregulation and oxidative stress. Curren...
Cx43 modulates malignant phenotypes in bladder cancer cells via the c-Src/PTEN/FAK axis
Cx43 modulates malignant phenotypes in bladder cancer cells via the c-Src/PTEN/FAK axis
Bladder cancer (BC), a leading urogenital malignancy with high mortality, lacks effective early biomarkers. Connexin 43 (C...
Protective role of Actovegin against Cisplatin-evoked testicular damage: evidence from a rat model
Protective role of Actovegin against Cisplatin-evoked testicular damage: evidence from a rat model
Testicular dysfunction and infertility are major concerns for men on Cisplatin. Excess reactive oxygen species produced by...
The anti-ulcerative potential of Berberine on the rat model of inflammatory bowel disease
The anti-ulcerative potential of Berberine on the rat model of inflammatory bowel disease
Ulcerative colitis (UC) is a global inflammatory bowel disease (IBD) and is a chronic mucosal inflammation of the large in...
Effects of  extract on burn wound healing in streptozotocin-induced diabetic rats: a pathological and molecular evaluation
Effects of extract on burn wound healing in streptozotocin-induced diabetic rats: a pathological and molecular evaluation
This study investigated the pathological and molecular effects of Centella asiatica extract–based cream and ointment...
QiangGuYin-containing serum improves osteogenic differentiation via regulating osteoclast-derived exosomal miR-27b-3p
QiangGuYin-containing serum improves osteogenic differentiation via regulating osteoclast-derived exosomal miR-27b-3p
Osteoclast-derived exosomes play a critical role in suppressing osteogenic differentiation, contributing to postmenopausal...
Nell-1 inhibits osteoclast differentiation and bone resorption in apical periodontitis
Nell-1 inhibits osteoclast differentiation and bone resorption in apical periodontitis
Apical periodontitis (AP) is characterized by progressive osteoclast-mediated bone destruction. Although Nell-1 may inhibi...
Circadian rhythm disruption affects cellular senescence through the BMAL1/CRY2/PER1 signaling pathway in periodontitis
Circadian rhythm disruption affects cellular senescence through the BMAL1/CRY2/PER1 signaling pathway in periodontitis
Accelerated cellular senescence may be a key process in the progression of periodontitis, as it integrates the devastating...
Interplay between miR-21 and mTOR signaling in an experimental mouse model of polycystic ovary syndrome
Interplay between miR-21 and mTOR signaling in an experimental mouse model of polycystic ovary syndrome
Polycystic ovary syndrome (PCOS), one of the leading causes of anovulatory infertility, is a complex endocrinopathy influe...
The TRAF6-TXNIP-NLRP3 signaling axis regulates LPS-induced pyroptosis in glomerular podocytes
The TRAF6-TXNIP-NLRP3 signaling axis regulates LPS-induced pyroptosis in glomerular podocytes
This study investigated the role of TNF receptor associated factor 6 (TRAF6) in glomerular podocyte pyroptosis. An in vitr...
DNMT3a mediates FSTL3 methylation to regulate trophoblast proliferation, migration and invasion
DNMT3a mediates FSTL3 methylation to regulate trophoblast proliferation, migration and invasion
The substantial incidence and mortality rates of preeclampsia (PE) have drawn significant international attention. DNA met...
The potential role of SCF combined with DPCs in facial nerve repair
The potential role of SCF combined with DPCs in facial nerve repair
Facial nerve injuries lead to significant functional impairments and psychological distress for affected patients. Effecti...
Activation of the WNT4/ β-catenin/FOXO1 pathway by PDK1 promotes cervical cancer metastasis and EMT process
Activation of the WNT4/ β-catenin/FOXO1 pathway by PDK1 promotes cervical cancer metastasis and EMT process
This study aimed to elucidate the role of pyruvate dehydrogenase kinase-1 (PDK1) in cervical cancer (CC) by investigating ...
MiRNAs and tempol therapeutic potential in prostate cancer: a preclinical approach
MiRNAs and tempol therapeutic potential in prostate cancer: a preclinical approach
This study investigated tempol action on genes and miRNAs related to NFκB pathway in androgen dependent or independen...
Comparative analysis with stem cell therapy in rats with pharyngocutaneous fistula formation
Comparative analysis with stem cell therapy in rats with pharyngocutaneous fistula formation
Laryngocutaneous fistula is one of the most important complications encountered after larynx surgery. Stem cell therapy is...
Gallic acid mitigates lipopolysaccharide-induced testicular inflammation via regulation of the NF-κB and PK2/PKR1 pathway
Gallic acid mitigates lipopolysaccharide-induced testicular inflammation via regulation of the NF-κB and PK2/PKR1 pathway
Genital tract infections are common causes of male infertility, and most of diagnosed men are asymptomatic. This study exa...
LINC02418 suppresses endometrial cancer progression via regulating miR-494-3p/RASGRF1 axis
LINC02418 suppresses endometrial cancer progression via regulating miR-494-3p/RASGRF1 axis
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulatory molecules in cancer biology. Among these, long intergeni...
Persimmon (Diospyros kaki L.) leaves accelerates skin tissue regeneration in excisional wound model: possible molecular mechanisms
Persimmon (Diospyros kaki L.) leaves accelerates skin tissue regeneration in excisional wound model: possible molecular mechanisms
Persimmon (Diospyros kaki L.) leaves are a traditional medicinal herb used for treating many infectious and inflammatory-r...
A determination of the main regulators of necroptosis in testicular tissue under different heat stresses
A determination of the main regulators of necroptosis in testicular tissue under different heat stresses
Although minimal increases in testicular temperature can compromise spermatogenesis and lead to fertility-related problems...
The effects of prenatal administration of tumor necrosis factor-α on osteocalcin and RANK expression in newborn mice
The effects of prenatal administration of tumor necrosis factor-α on osteocalcin and RANK expression in newborn mice
Tumor necrosis factor-α (TNF-α) induces a multitude of actions and consequences in bone and cartilage resorption...