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Prediagnostic serum 25‐hydroxyvitamin D and leptin in relation to melanoma‐specific and overall death
Prediagnostic serum 25‐hydroxyvitamin D and leptin in relation to melanoma‐specific and overall death
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Ulcerated melanoma: Systems biology evidence of inflammatory imbalance towards pro‐tumourigenicity
Ulcerated melanoma: Systems biology evidence of inflammatory imbalance towards pro‐tumourigenicity
Abstract Microscopic ulceration is an independent predictor of melanoma death. Here, we used systems biology to query the ...
Eosinophils and Melanoma: Implications for Immunotherapy
Eosinophils and Melanoma: Implications for Immunotherapy
ABSTRACT New therapies such as immune checkpoint blockers (ICB) have offered extended survival to patients affected by adv...
The feather pattern autosomal barring in chicken is strongly associated with segregation at the MC1R locus
The feather pattern autosomal barring in chicken is strongly associated with segregation at the MC1R locus
Abstract Color patterns within individual feathers are common in birds but little is known about the genetic mechanisms ca...
Non‐Steroidal Anti‐Inflammatory Drugs (NSAIDs) sensitize melanoma cells to MEK inhibition and inhibit metastasis and relapse by inducing degradation of AXL
Non‐Steroidal Anti‐Inflammatory Drugs (NSAIDs) sensitize melanoma cells to MEK inhibition and inhibit metastasis and relapse by inducing degradation of AXL
Abstract Melanoma is highly heterogeneous with diverse genomic alterations and partial therapeutic responses. The emergenc...
Impact of a SLC24A5 variant on the retinal pigment epithelium of a Japanese patient with oculocutaneous albinism type 6
Impact of a SLC24A5 variant on the retinal pigment epithelium of a Japanese patient with oculocutaneous albinism type 6
Abstract Oculocutaneous albinism (OCA) 6 is a non-syndromic type of OCA that has distinct ocular symptoms and variable cut...
Volar location and degree of pigmentation are associated with poor survival and first metastasis pattern in acral melanoma
Volar location and degree of pigmentation are associated with poor survival and first metastasis pattern in acral melanoma
Abstract The risk factors affecting acral melanoma metastasis and prognosis remain unclear. The study included 168 patient...
Genetic analysis of multiple primary melanomas arising within the boundaries of congenital nevi depigmentosa
Genetic analysis of multiple primary melanomas arising within the boundaries of congenital nevi depigmentosa
Abstract Here, we present a rare case of a patient who developed multiple primary melanomas within the boundaries of two n...
Ulcerated Melanoma: Systems Biology Evidence of Inflammatory Imbalance Toward Pro‐tumorigenicity
Ulcerated Melanoma: Systems Biology Evidence of Inflammatory Imbalance Toward Pro‐tumorigenicity
Abstract Microscopic ulceration is an independent predictor of melanoma death. Here we used systems biology to query the r...
List of reviewers for PCMR (01.01.2021–30.09.2021)
List of reviewers for PCMR (01.01.2021–30.09.2021)
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New insights into segmental vitiligo: a clinical and immunological comparison with nonsegmental vitiligo
New insights into segmental vitiligo: a clinical and immunological comparison with nonsegmental vitiligo
Abstract The overlaps between segmental vitiligo (SV) and nonsegmental vitiligo (NSV) suggest the underlying features of S...
NSAIDs Sensitize Melanoma Cells to MEK Inhibition and Inhibit Metastasis and Relapse by Inducing Degradation of AXL
NSAIDs Sensitize Melanoma Cells to MEK Inhibition and Inhibit Metastasis and Relapse by Inducing Degradation of AXL
Abstract Melanoma is highly heterogeneous with diverse genomic alterations and partial therapeutic responses. Emergence of...
Molecular characterization of biphenotypic epithelioid and plexiform melanoma with deep penetrating nevus‐like features
Molecular characterization of biphenotypic epithelioid and plexiform melanoma with deep penetrating nevus‐like features
Abstract Tumor heterogeneity is a relevant hallmark of melanoma due to the high mutation burden and immunogenicity commonl...
Molecular characterization of biphenotypic epithelioid and plexiform melanoma with deep penetrating nevus (DPN)‐like features
Molecular characterization of biphenotypic epithelioid and plexiform melanoma with deep penetrating nevus (DPN)‐like features
Abstract Tumor heterogeneity is a relevant hallmark of melanoma due to the high mutation burden and immunogenicity commonl...
Intragenic NF1 deletions in sinonasal mucosal malignant melanoma
Intragenic NF1 deletions in sinonasal mucosal malignant melanoma
Abstract Mucosal malignant melanoma (MMM) is a rare and aggressive tumor. Despite effective local therapies, tumor recurre...
The ERK signaling pathway returns to the limelight in uveal melanomas
The ERK signaling pathway returns to the limelight in uveal melanomas
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Human TYRP1: Two functions for a single gene?
Human TYRP1: Two functions for a single gene?
Abstract In the animal kingdom, skin pigmentation is highly variable between species, and it contributes to phenotypes. In...
Connexins in melanoma: Potential role of Cx46 in its aggressiveness
Connexins in melanoma: Potential role of Cx46 in its aggressiveness
Abstract Melanoma is the most aggressive skin cancer, and in metastatic advanced states, it is completely refractory to ch...
Investigating DNA methylation as a potential mediator between pigmentation genes, pigmentary traits and skin cancer
Investigating DNA methylation as a potential mediator between pigmentation genes, pigmentary traits and skin cancer
Abstract Pigmentation characteristics are well-known risk factors for skin cancer. Polymorphisms in pigmentation genes hav...
Immune‐modulatory effects of lenalidomide inhibited the progression of lesions in a vitiligo mouse model
Immune‐modulatory effects of lenalidomide inhibited the progression of lesions in a vitiligo mouse model
Abstract Vitiligo, an autoimmune disorder, is associated with altered cytokine levels and T lymphocytes. Lenalidomide modu...
First‐line atezolizumab monotherapy in patients with advanced BRAFV600 wild‐type melanoma
First‐line atezolizumab monotherapy in patients with advanced BRAFV600 wild‐type melanoma
Abstract Anti-programmed death-1 agents are an established option for advanced melanoma, but the anti-programmed death-lig...
Germline variants in exonic regions have limited impact on immune checkpoint blockade clinical outcomes in advanced melanoma
Germline variants in exonic regions have limited impact on immune checkpoint blockade clinical outcomes in advanced melanoma
Abstract Immune checkpoint inhibition (ICI) treatments improve outcomes for metastatic melanoma; however, up to 60% of tre...
Strategies in DNA vaccine for melanoma cancer
Strategies in DNA vaccine for melanoma cancer
Abstract According to reports of the international agency for cancer on research, although malignant melanoma shows less p...
Neratinib kills B‐RAF V600E melanoma via ROS‐dependent autophagosome formation and death receptor signaling
Neratinib kills B‐RAF V600E melanoma via ROS‐dependent autophagosome formation and death receptor signaling
Abstract Melanoma cells expressing mutant B-RAF V600E are susceptible to treatment with the combination of a B-RAF inhibit...
Phenotypic plasticity of melanocytes derived from human adult skin
Phenotypic plasticity of melanocytes derived from human adult skin
Abstract We previously described a novel in vitro culture technique for dedifferentiated human adult skin melanocytes. Mel...
YAP facilitates melanoma migration through regulation of actin‐related protein 2/3 complex subunit 5 (ARPC5)
YAP facilitates melanoma migration through regulation of actin‐related protein 2/3 complex subunit 5 (ARPC5)
Abstract Yes-associated protein 1 (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are transcriptional c...
The Role of Ferroptosis in Melanoma
The Role of Ferroptosis in Melanoma
Abstract Melanoma is the deadliest form of skin cancer. Although treatment with targeted therapies and immune checkpoint i...
Drosophila yellow‐h encodes dopaminechrome tautomerase: A new enzyme in the eumelanin biosynthetic pathway
Drosophila yellow‐h encodes dopaminechrome tautomerase: A new enzyme in the eumelanin biosynthetic pathway
Abstract Melanin is a widely distributed phenolic pigment that is biosynthesized from tyrosine and its hydroxylated produc...
The impaired unfolded protein‐premelanosome protein and transient receptor potential channels‐autophagy axes in apoptotic melanocytes in vitiligo
The impaired unfolded protein‐premelanosome protein and transient receptor potential channels‐autophagy axes in apoptotic melanocytes in vitiligo
Abstract Vitiligo is an autoimmune skin disease, characterized by depigmentation and epidermal melanocytes loss. The speci...
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