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Heterogeneity of Sox2-expressing cells in mouse pituitary and their roles in postnatal gonadotroph differentiation
The role of stem/progenitor cells (hereafter referred to as stem cells) in the development of the embryonic pituitary is w...
The role of IGFBP7 in the immune regulation of PCOS-like symptoms based on spleen transcriptome and TCR β CDR3 repertoire analysis
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive age, characterized by h...
PACAP inhibits high fat-induced NLRP3 inflammasome-mediated pyroptosis in vascular endothelial cells by regulating the SIRT1/ROS pathway
Lipid metabolism disorders lead to elevated levels of free fatty acids (FFA) in plasma, which are closely associated with ...
4T1 breast cancer cells exposed to extracellular vesicles from MDA-MB-231 cells stimulated with Bisphenol A increase the growth of mammary tumors and metastasis in female Balb/cJ mice
Breast cancer is the most prevalent neoplasia in women worldwide. Triple negative breast cancer (TNBC) is a subtype charac...
Mitochondrial dysfunction and defective quality control mechanisms in the kidney are not reversed by high-fat diet withdrawal in early obese mice
High fat diet (HFD) induces glomerulopathy and proximal tubule injury. The precise pathophysiological mechanisms triggerin...
Sex-specific differences in the influence of maternal obesity on the oxidative and inflammatory status in the maternal-placental-fetal unit: new insights into the placental sphingolipid profile
Although maternal obesity influences placental and fetal development, the underlying molecular mechanisms have yet to be d...
Deciphering the allosteric control of androgen receptor DNA binding by its disordered N-terminal domain
The androgen receptor (AR) plays a pivotal role in male physiological development and is implicated in the pathogenesis of...
Breaking immune evasion in breast cancer by targeting COX-2/PGE2 pathway
Breast cancer (BC) is the most common malignancy among women worldwide and is associated with significant metabolic reprog...
The role of the mineralocorticoid receptor in skin
The mineralocorticoid receptor (MR) plays a pivotal role in skin homeostasis, inflammation, and repair, interacting closel...
Corrigendum to “The BRAFV600E mutation maintains the aggressiveness of papillary thyroid cancers requiring downregulation of primary cilia” [Mol. Cell. Endocrinol. 581 (2024) 112113]
Volume 608, 1 October 2025, 112626Author links open overlay panelCheng-Xu Ma a b, Xiao-Ni Ma a b, Jin-Jin Liu a b, Cong-Hu...
Adipose tissue-specific Yap knockout exacerbates diet-induced obesity through suppression of lipolysis
Obesity is a chronic metabolic disorder pathologically defined by sustained positive energy balance (energy intake > en...
Transcriptomic modifications in maternal pancreatic islets during the period around weaning in mice
Identifying the mechanisms and molecular factors that enhance beta-cell mass is crucial for developing strategies to comba...
MeCP2 attenuates inflammation and regulates T cell phenotype via SFRP4 suppression in preeclampsia
Preeclampsia (PE) is the second leading cause of maternal mortality worldwide and contributes significantly to maternal mo...
Epigenetic regulation of sex: the role of DNA methylation and zbtb38 in zebrafish sex differentiation and heat-induced masculinization
There is increasing evidence that global change can threaten biodiversity by inducing skewed sex ratios. Accumulating evid...
α-Linolenic acid rich-chia seed improves glucose tolerance, modulates gluconeogenic pathway and hepatic insulin signaling in an experimental model of metabolic syndrome
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the latest term for a steatotic liver disease associat...
The N-terminal region of HASPIN regulates phosphorylation of AURKA and meiotic progression in spermatocytes
Spermatogenesis is an extremely complex and tightly regulated biological process that generates streamlined sperm capable ...
Developmental programming: Differing impact of prenatal testosterone and prenatal bisphenol-A -treatment on hepatic methylome in female sheep
Steroid hormones are integral to pregnancy and fetal development, regulating processes such as metabolism, inflammation, a...
Impact of novel amino acid substituted and acylated spexin analogues on pancreatic beta-cell function, appetite and glucose homeostasis
ObjectiveThe neuropeptide spexin is recognised as a satiety-inducing hormone, but overall effects on metabolism are less c...
Three-dimensional (3D) pancreatic β-cell models reveal insulin-secretion enhancing potential of green synthesized silver nanoparticles
Diabetes is one of the rapidly increasing chronic diseases in the world, and according to International Diabetes Federatio...
Oocyte-specific Ahr deletion disrupts folliculogenesis and female fertility in mice
The aryl hydrocarbon receptor (AHR) is a nuclear transcription factor widely expressed in various organisms. Since its dis...
Endocrine Disruptors Chemicals: Impacts of Bisphenol A, Tributyltin and Lead on Thyroid Function
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Chemerin mediates exercise-induced improvements of bone microstructure and bone mass in diabetes or high fat diet mice
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Bisphenol A-Induced Cancer-Associated Adipocytes Promotes Breast Carcinogenesis Via CXCL12/AKT Signaling
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Dietary Advanced Glycation End Products and Superovulation with Gonadotropins Alters RAGE expression in the Ovaries Differently at Each Follicular Stage of Development
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The impact of obesity on mitochondrial dysfunction during pregnancy
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Housing temperature influences metabolic phenotype of heart failure with preserved ejection fraction in J vs N strain C57BL/6 mice
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Functional analysis of SRY variants in individuals with 46,XY differences of sex development
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EDNRB negatively regulates glycolysis to exhibit anti-tumor functions in prostate cancer by cGMP/PKG pathway
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A guide to pathophysiology, signaling pathways, and preclinical models of liver fibrosis
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Endocrine-disrupting chemical, methylparaben, in environmentally relevant exposure promotes hazardous effects on the hypothalamus-pituitary-thyroid axis
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