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BMP4 preserves the developmental potential of mESCs through - and -mediated chromosomal stability safeguarding
BMP4 preserves the developmental potential of mESCs through - and -mediated chromosomal stability safeguarding
Chemically defined medium is widely used for culturing mouse embryonic stem cells (mESCs), in which N2B27 works as a subst...
Metabolic reprogramming and epigenetic modifications on the path to cancer
Metabolic reprogramming and epigenetic modifications on the path to cancer
Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally regulate each other, are among the...
A world renowned psychophysiologist: Kaoliang Chow
A world renowned psychophysiologist: Kaoliang Chow
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Tsai Chiao: The founder of physiology and aviation, aerospace and navigation medicine in China
Tsai Chiao: The founder of physiology and aviation, aerospace and navigation medicine in China
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Qi Fang: Affective interweave with patients
Qi Fang: Affective interweave with patients
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The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics
The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics
Extracellular vesicles (EVs) are tiny biological nanovesicles ranging from approximately 30–1000 nm in diameter that...
Darwinian rebel: The legacy of Loh-Seng Tsai—Chinese animal psychologist
Darwinian rebel: The legacy of Loh-Seng Tsai—Chinese animal psychologist
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Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2
Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2
In the original publication the author’s name ‘Dimitri Lavillete’ is published incorrectly. The correct ...
Chia Chi Wang and his research on Protozoology
Chia Chi Wang and his research on Protozoology
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Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda
Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda
The fall armyworm (FAW), Spodoptera frugiperda, is a destructive pest native to America and has recently become an invasiv...
Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies
Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies
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Molecular basis and homeostatic regulation of Zinc taste
Molecular basis and homeostatic regulation of Zinc taste
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The hypothalamus for whole-body physiology: from metabolism to aging
The hypothalamus for whole-body physiology: from metabolism to aging
Obesity and aging are two important epidemic factors for metabolic syndrome and many other health issues, which contribute...
Correction to: Gonadal mosaicism mediated female-biased gender control in mice
Correction to: Gonadal mosaicism mediated female-biased gender control in mice
In the original article, there were some errors in the funding part and in this correction, the correct funding text is as...
Correction to: mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells
Correction to: mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells
State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 10...
The early days of structural biology at the Beijing Institute of Biophysics: In memory of Professor Zhengjiong Lin (1935–2022)
The early days of structural biology at the Beijing Institute of Biophysics: In memory of Professor Zhengjiong Lin (1935–2022)
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Connecting past and present: single-cell lineage tracing
Connecting past and present: single-cell lineage tracing
Central to the core principle of cell theory, depicting cells’ history, state and fate is a fundamental goal in mode...
Sicien H. Chen, one of the pioneers and founders of Chinese entomology
Sicien H. Chen, one of the pioneers and founders of Chinese entomology
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Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosis
Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosis
Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce cardiovascular mortality in patients with diabetes mellitus but t...
Comprehensive analysis of RNA-seq and whole genome sequencing data reveals no evidence for SARS-CoV-2 integrating into host genome
Comprehensive analysis of RNA-seq and whole genome sequencing data reveals no evidence for SARS-CoV-2 integrating into host genome
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The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication
The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication
Rice stripe virus (RSV) transmitted by the small brown planthopper causes severe rice yield losses in Asian countries. Alt...
Homology-based repair induced by CRISPR-Cas nucleases in mammalian embryo genome editing
Homology-based repair induced by CRISPR-Cas nucleases in mammalian embryo genome editing
Recent advances in genome editing, especially CRISPR-Cas nucleases, have revolutionized both laboratory research and clini...
Postnatal state transition of cardiomyocyte as a primary step in heart maturation
Postnatal state transition of cardiomyocyte as a primary step in heart maturation
Postnatal heart maturation is the basis of normal cardiac function and provides critical insights into heart repair and re...
FTO stabilizes MIS12 and counteracts senescence
FTO stabilizes MIS12 and counteracts senescence
We are grateful to Lei Bai, Ruijun Bai, Qun Chu, Shikun Ma, Jing Lu, Luyang Tian and Ying Yang for their administrative as...
Targeting papain-like protease for broad-spectrum coronavirus inhibition
Targeting papain-like protease for broad-spectrum coronavirus inhibition
The emergence of SARS-CoV-2 variants of concern and repeated outbreaks of coronavirus epidemics in the past two decades em...
SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation
SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation
The nucleocapsid (N) protein of SARS-CoV-2 has been reported to have a high ability of liquid-liquid phase separation, whi...
Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques
Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques
SARS-CoV-2 infection causes complicated clinical manifestations with variable multi-organ injuries, however, the underlyin...
New pathogenic insights from large animal models of neurodegenerative diseases
New pathogenic insights from large animal models of neurodegenerative diseases
Animal models are essential for investigating the pathogenesis and developing the treatment of human diseases. Identificat...
Gonadal mosaicism mediated female-biased gender control in mice
Gonadal mosaicism mediated female-biased gender control in mice
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Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells
Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells
The eukaryotic genome is folded into higher-order conformation accompanied with constrained dynamics for coordinated genom...
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