SCI Abstract

search
+
Effects of preoperative recombinant Interleukin 2-based immunomodulation on outcome after gastrointestinal cancer surgery: a systematic review and meta-analysis
Effects of preoperative recombinant Interleukin 2-based immunomodulation on outcome after gastrointestinal cancer surgery: a systematic review and meta-analysis
Patients undergoing gastrointestinal cancer surgery are often immunocompromised and susceptible to infectious complication...
Retraction Note: CDK5RAP3 as tumour suppressor negatively regulates self-renewal and invasion and is regulated by ERK1/2 signalling in human gastric cancer
The Editor-in-Chief has retracted this article because the authors have not provided documents confirming that appropriate...
Correction: Exposure-response relationship of cabozantinib in patients with metastatic renal cell carcinoma treated in routine care
Université de Paris, CNRS, INSERM, CiTCoM, U1268, F-75006, Paris, FranceBenoit Blanchet & Michel VidalBiologie du Médi...
Immunosuppressive immune microenvironment landscapes in VISTA-high gastric cancer
Immunosuppressive immune microenvironment landscapes in VISTA-high gastric cancer
V-domain Ig-containing suppressor of T cell activation (VISTA) is an immune checkpoint molecule predominantly expressed on...
Fasting-mimicking diet induces IFNβ secretion in tumor-associated macrophages via NRF1-mediated ubiquitin-dependent proteolysis of Trex1
Fasting-mimicking diet induces IFNβ secretion in tumor-associated macrophages via NRF1-mediated ubiquitin-dependent proteolysis of Trex1
Fasting-mimicking diet (FMD) is a safe and effective strategy in clinical oncology via metabolically restricting tumour gr...
Modelled impact of a multi-cancer early detection screening programme on the demand for diagnostics in England
Modelled impact of a multi-cancer early detection screening programme on the demand for diagnostics in England
People with a cancer signal detected via multi-cancer early detection (MCED) screening need timely access to confirmatory ...
Real-world use and survival outcomes of sacituzumab govitecan in metastatic triple-negative breast cancer and hormone receptor-positive/HER2-negative metastatic breast cancer
Real-world use and survival outcomes of sacituzumab govitecan in metastatic triple-negative breast cancer and hormone receptor-positive/HER2-negative metastatic breast cancer
Sacituzumab govitecan (SG) was granted early access in France as third-line therapy for metastatic triple-negative breast ...
Exposure-response relationship of nivolumab and ipilimumab in patients with metastatic renal cell carcinoma from the randomised phase 2 BIONIKK study
Exposure-response relationship of nivolumab and ipilimumab in patients with metastatic renal cell carcinoma from the randomised phase 2 BIONIKK study
We aimed to investigate the exposure-response (E/R) relationship for ipilimumab and nivolumab in metastatic clear cell ren...
Statin use and breast cancer-specific mortality and recurrence: a systematic review and meta-analysis including the role of immortal time bias and tumour characteristics
Statin use and breast cancer-specific mortality and recurrence: a systematic review and meta-analysis including the role of immortal time bias and tumour characteristics
The association between statins and breast cancer-specific mortality and recurrence has been examined in several previous ...
Growth kinetics of high-grade serous ovarian cancer: implications for early detection
Growth kinetics of high-grade serous ovarian cancer: implications for early detection
High-grade serous ovarian cancer (HGSOC) is the most lethal gynaecological cancer with patients routinely diagnosed at adv...
Association between methylation quantitative trait loci and colorectal cancer risk, survival and cancer recurrence
Association between methylation quantitative trait loci and colorectal cancer risk, survival and cancer recurrence
Epigenetic changes contribute to colorectal cancer (CRC) pathogenesis. We investigated whether methylation quantitative tr...
Increased cancer risk in kidney transplant patients in Scotland: a national registry linkage study
Increased cancer risk in kidney transplant patients in Scotland: a national registry linkage study
Cancer is a major contributor to morbidity following kidney transplantation. This study examines the incidence of cancer i...
Correction: Targeting autophagy reverses de novo resistance in homologous recombination repair proficient breast cancers to PARP inhibition
In Fig 5c, some of the representative images of treatments in MCF 7 cells we...
Correction: Multicenter phase Ib/II study of second-line durvalumab and tremelimumab in combination with paclitaxel in patients with biomarker-selected metastatic gastric cancer
Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine...
Correction: E2F7−EZH2 axis regulates PTEN/AKT/mTOR signalling and glioblastoma progression
Correction: E2F7−EZH2 axis regulates PTEN/AKT/mTOR signalling and glioblastoma progression
Key Laboratory of Precision Oncology of Shandong Higher Education, Institute of Precision Medicine, Jining Medical Univers...
VASN drives gastric tumorigenesis via activation of the COL4A1/PI3K/AKT axis during Helicobacter pylori infection
VASN drives gastric tumorigenesis via activation of the COL4A1/PI3K/AKT axis during Helicobacter pylori infection
Vasorin (VASN) is linked to tumor progression in various cancers, its role and regulatory mechanisms in gastric cancer (GC...
Integrated genomic and transcriptomic analysis reveals the activation of PI3K signaling pathway in HPV-independent cervical cancers
Integrated genomic and transcriptomic analysis reveals the activation of PI3K signaling pathway in HPV-independent cervical cancers
HPV-independent cervical cancers (HPV-ind CCs) are uncommon with worse prognosis and poorly understood. This study investi...
Metabolic heterogeneity affects trastuzumab response and survival in HER2-positive advanced gastric cancer
Metabolic heterogeneity affects trastuzumab response and survival in HER2-positive advanced gastric cancer
Trastuzumab is the only first-line treatment targeted against the human epidermal growth factor receptor 2 (HER2) approved...
Exposure-response relationship of cabozantinib in patients with metastatic renal cell carcinoma treated in routine care
Exposure-response relationship of cabozantinib in patients with metastatic renal cell carcinoma treated in routine care
Interindividual pharmacokinetic variability may influence the clinical benefit or toxicity of cabozantinib in metastatic r...
Urinary microbiome-based metagenomic signature for the noninvasive diagnosis of hepatocellular carcinoma
Urinary microbiome-based metagenomic signature for the noninvasive diagnosis of hepatocellular carcinoma
Gut microbial dysbiosis is implicated in chronic liver disease and hepatocellular carcinoma (HCC), but the role of microbi...
Farnesyl-transferase inhibitors show synergistic anticancer effects in combination with novel KRAS-G12C inhibitors
Farnesyl-transferase inhibitors show synergistic anticancer effects in combination with novel KRAS-G12C inhibitors
Inhibition of mutant KRAS challenged cancer research for decades. Recently, allele-specific inhibitors were approved for t...
wMKL: multi-omics data integration enables novel cancer subtype identification via weight-boosted multi-kernel learning
wMKL: multi-omics data integration enables novel cancer subtype identification via weight-boosted multi-kernel learning
Cancer is a heterogeneous disease driven by complex molecular alterations. Cancer subtypes determined from multi-omics dat...
Albendazole inhibits colon cancer progression and therapy resistance by targeting ubiquitin ligase RNF20
Albendazole inhibits colon cancer progression and therapy resistance by targeting ubiquitin ligase RNF20
The repurposing of FDA-approved drugs for anti-cancer therapies is appealing due to their established safety profiles and ...
Rethinking surgical revisions: impact of the MonarchE trial on axillary dissection in hormone-positive HER2-negative early breast cancer patients potentially eligible for abemaciclib
Rethinking surgical revisions: impact of the MonarchE trial on axillary dissection in hormone-positive HER2-negative early breast cancer patients potentially eligible for abemaciclib
The MonarchE trial explored the use of abemaciclib, a CDK4/6 inhibitor, as an adjuvant treatment in high-risk early-stage ...
The presenting symptom signatures of incident cancer: evidence from the English 2018 National Cancer Diagnosis Audit
The presenting symptom signatures of incident cancer: evidence from the English 2018 National Cancer Diagnosis Audit
Understanding relationships between presenting symptoms and subsequently diagnosed cancers can inform symptom awareness ca...
Epithelial ovarian cancer survival by race and ethnicity in an equal-access healthcare population
Previous studies in the general population observed that compared with non-Hispanic White women, Pacific Islander and Blac...
Correction: Efficacy of GV1001 with gemcitabine/capecitabine in previously untreated patients with advanced pancreatic ductal adenocarcinoma having high serum eotaxin levels (KG4/2015): an open-label, randomised, Phase 3 trial
Division of Gastroenterology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, ...
Fatal and non-fatal breast cancers in women targeted by BreastScreen Norway: a cohort study
Fatal and non-fatal breast cancers in women targeted by BreastScreen Norway: a cohort study
Many breast cancer survivors experience anxiety related to dying from their disease even if it is detected at an early sta...
Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia
Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia
Alterations of FLT3 are among the most common driver events in acute leukaemia with important clinical implications, since...
Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer
Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer
The determinants of metastasis in mismatch repair deficiency with high levels of microsatellite instability (MSI-H) in col...
Load More
format_indent_increase