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Advances in endometrial cancer screening: a comprehensive review of current methods and emerging technologies
Advances in endometrial cancer screening: a comprehensive review of current methods and emerging technologies
Endometrial cancer represents a major global health concern, with rising incidence particularly in developed countries des...
Microflora: a promising potential in the diagnosis and treatment of non-small cell lung cancer
Microflora: a promising potential in the diagnosis and treatment of non-small cell lung cancer
The incidence and mortality of non-small cell lung cancer (NSCLC) remain high in China. Recently, several studies have sho...
Real-world experience of circulating tumor DNA testing in resectable colorectal cancer: a Japanese single-institution observational study
Real-world experience of circulating tumor DNA testing in resectable colorectal cancer: a Japanese single-institution observational study
Assessment of molecular residual disease (MRD) using circulating tumor DNA (ctDNA) is a powerful prognostic tool for detec...
Prognostic and clinicopathological implications of mismatch-repair deficiency and promoter methylation status in endometrial carcinoma
Prognostic and clinicopathological implications of mismatch-repair deficiency and promoter methylation status in endometrial carcinoma
The prevalence of MSI-H and MLH1 promoter hypermethylation (MLH1-PHM) as well as Lynch syndrome in Japanese patients with ...
Radiotherapy with or without chemotherapy for T2N0 hypopharyngeal cancer: an analysis of the head and neck cancer registry of Japan
Radiotherapy with or without chemotherapy for T2N0 hypopharyngeal cancer: an analysis of the head and neck cancer registry of Japan
This retrospective study compared the outcomes of radiotherapy (RT) and chemoradiotherapy (CRT) in patients with T2N0 hypo...
Impact of baseline regular magnesium oxide administration on chemotherapy-induced constipation during cisplatin-containing treatment
Impact of baseline regular magnesium oxide administration on chemotherapy-induced constipation during cisplatin-containing treatment
Chemotherapy-induced constipation frequently occurs with cisplatin-containing treatments, partly because of concomitant ne...
Long-term progression-free survivors (“super responders”) to olaparib maintenance in recurrent ovarian cancer: a multicenter real-world study (KCOG-G2101s)
Long-term progression-free survivors (“super responders”) to olaparib maintenance in recurrent ovarian cancer: a multicenter real-world study (KCOG-G2101s)
PARP inhibitors have been shown to improve progression-free survival in patients with recurrent ovarian cancer. However, t...
The impact of neutropenia severity in the setting of recent chemotherapy on mortality in sepsis
The impact of neutropenia severity in the setting of recent chemotherapy on mortality in sepsis
Sepsis and septic shock are major causes of non-relapse mortality in cancer patients, with chemotherapy-induced neutropeni...
Cancer epidemiology in rare and hereditary colorectal diseases 2) anal canal cancer (cancer statistics)
Cancer epidemiology in rare and hereditary colorectal diseases 2) anal canal cancer (cancer statistics)
Anal canal carcinoma (ACC) is reported to be a rare cancer worldwide. In Japan, while the incidence rate is similarly low ...
Longitudinal assessment of health-related quality of life, sleep quality, and gustation in patients with advanced urothelial carcinoma receiving late-line enfortumab vedotin monotherapy
Longitudinal assessment of health-related quality of life, sleep quality, and gustation in patients with advanced urothelial carcinoma receiving late-line enfortumab vedotin monotherapy
To describe real-world data on health-related quality of life (HRQoL) in patients with locally advanced or metastatic urot...
Sequential changes in conditional survival of patients following surgical resection of colorectal cancer and indicators for follow-up beyond 5 years
Sequential changes in conditional survival of patients following surgical resection of colorectal cancer and indicators for follow-up beyond 5 years
The evolving prognosis of colorectal cancer (CRC) over extended periods following surgery has not been comprehensively cha...
Real-world effectiveness and safety of lisocabtagene maraleucel for relapsed/refractory large B cell lymphoma in Japan
Real-world effectiveness and safety of lisocabtagene maraleucel for relapsed/refractory large B cell lymphoma in Japan
Lisocabtagene maraleucel (liso-cel), an anti-CD19 CAR T cell therapy, has demonstrated efficacy in relapsed/refractory (R/...
Real-world safety and efficacy of immune checkpoint inhibitors in Japanese patients with persistent, recurrent, or metastatic cervical cancer: a multicenter prospective and retrospective study
Real-world safety and efficacy of immune checkpoint inhibitors in Japanese patients with persistent, recurrent, or metastatic cervical cancer: a multicenter prospective and retrospective study
To evaluate the real-world safety and efficacy of immune checkpoint inhibitors (ICIs) in Japanese patients with persistent...
Lack of molecular mimicry between HPV vaccine L1 antigen and human proteins by a computational analysis
Lack of molecular mimicry between HPV vaccine L1 antigen and human proteins by a computational analysis
Although human papillomavirus (HPV) vaccines effectively prevent cervical cancer, the HPV vaccination rates in Japan remai...
Current development and challenges of NK cell-based immunotherapy for gastrointestinal cancers
Current development and challenges of NK cell-based immunotherapy for gastrointestinal cancers
Despite multimodal treatment options, most gastrointestinal (GI) cancers remain associated with high mortality rates and p...
Efficacy and safety of subcutaneous mosunetuzumab in combination with lenalidomide and as a monotherapy in Japanese patients with relapsed/refractory follicular lymphoma
Efficacy and safety of subcutaneous mosunetuzumab in combination with lenalidomide and as a monotherapy in Japanese patients with relapsed/refractory follicular lymphoma
JO40295 (jRCT2080223801) evaluated the efficacy and safety of subcutaneous (SC) mosunetuzumab, in combination with lenalid...
F-PSMA-PET/CT in comparison with whole-body MRI and combination of conventional CT and bone scintigraphy for detection of recurrent disease in prostate cancer patients with rising PSA levels after initial definitive treatment
F-PSMA-PET/CT in comparison with whole-body MRI and combination of conventional CT and bone scintigraphy for detection of recurrent disease in prostate cancer patients with rising PSA levels after initial definitive treatment
The purpose of this study was to compare the diagnostic performance of radiolabeled prostate-specific membrane antigen-tar...
The prognostic factors and treatment patterns of the first recurrence of retroperitoneal liposarcoma
The prognostic factors and treatment patterns of the first recurrence of retroperitoneal liposarcoma
This study aimed to identify prognostic factors and treatment patterns at the first recurrence of retroperitoneal liposarc...
Efficacy and safety of epcoritamab in Japanese patients with relapsed or refractory diffuse large B-cell lymphoma: 3-year follow-up from the EPCORE NHL-3 trial
Efficacy and safety of epcoritamab in Japanese patients with relapsed or refractory diffuse large B-cell lymphoma: 3-year follow-up from the EPCORE NHL-3 trial
Primary results from the EPCORE NHL-3 trial (NCT04542824) showed deep, durable responses in Japanese patients with relapse...
Phase-Ib dose-finding and pharmacokinetic trial of metformin combined with nivolumab for refractory/recurrent solid tumors
Phase-Ib dose-finding and pharmacokinetic trial of metformin combined with nivolumab for refractory/recurrent solid tumors
Our previous findings showed that the addition of metformin to nivolumab resulted in remarkable tumor regression and incre...
Collaborative frontiers in pediatric neuro-oncology: establishing an international tumor board for enhanced care and global impact
Collaborative frontiers in pediatric neuro-oncology: establishing an international tumor board for enhanced care and global impact
Central nervous system tumors are the leading cause of cancer-related mortality in children, with significant disparities ...
Impact of medications on the efficacy of immune checkpoint inhibitors in patients with recurrent or metastatic head and neck cancer
Impact of medications on the efficacy of immune checkpoint inhibitors in patients with recurrent or metastatic head and neck cancer
Immune checkpoint inhibitors (ICIs) are standard treatments for recurrent or metastatic head and neck cancer (RM-HNC). How...
Impact of cancer type differences on chemotherapy-induced nausea and vomiting (CINV) incidence in oxaliplatin-based regimens for gastric and colorectal cancer: a retrospective study
Impact of cancer type differences on chemotherapy-induced nausea and vomiting (CINV) incidence in oxaliplatin-based regimens for gastric and colorectal cancer: a retrospective study
The incidence of chemotherapy-induced nausea and vomiting (CINV) when using an oxaliplatin-based regimen may vary accordin...
Percutaneous cryoablation versus robot-assisted partial nephrectomy for small renal cell carcinoma: a retrospective cost analysis at Japanese single-institution
Percutaneous cryoablation versus robot-assisted partial nephrectomy for small renal cell carcinoma: a retrospective cost analysis at Japanese single-institution
No direct cost comparison has been conducted between percutaneous cryoablation (PCA) and robot-assisted partial nephrectom...
Narrative review of focal boost to intraprostatic dominant lesion in intensity-modulated radiation therapy for localized or locally advanced prostate cancer
Narrative review of focal boost to intraprostatic dominant lesion in intensity-modulated radiation therapy for localized or locally advanced prostate cancer
Local intraprostatic recurrence is one of the important recurrence patterns following definitive intensity-modulated radia...
Different outcomes by sex in metastatic gastrointestinal stromal tumor patients receiving imatinib: a trial-level analysis
Different outcomes by sex in metastatic gastrointestinal stromal tumor patients receiving imatinib: a trial-level analysis
Among gastrointestinal stromal tumors patients, many authors have reported longer overall survival for female sex regardle...
Physical activity and cancer biology: a narrative review of molecular mechanisms and introduction of the SCRUM-MONSTAR LIFELOG study
Physical activity and cancer biology: a narrative review of molecular mechanisms and introduction of the SCRUM-MONSTAR LIFELOG study
Physical activity (PA) has been consistently associated with improved cancer outcomes across multiple epidemiological stud...
A perspective on patient-derived orthotopic xenograft (PDOX) mouse models for identification of novel and individualized treatment for sarcoma
A perspective on patient-derived orthotopic xenograft (PDOX) mouse models for identification of novel and individualized treatment for sarcoma
Sarcomas, including osteosarcoma and soft tissue sarcoma, are heterogeneous and rare diseases with limited treatment optio...
Systematic review and meta-analysis of photon radiotherapy versus proton beam therapy for pediatric rhabdomyosarcoma: TRP-rhabdomyosarcoma 2024
Systematic review and meta-analysis of photon radiotherapy versus proton beam therapy for pediatric rhabdomyosarcoma: TRP-rhabdomyosarcoma 2024
Childhood cancer treatment has increasingly achieved favorable long-term survival rates, shifting focus toward reducing lo...
Impact of second-line combination chemotherapy on post-progression survival in metastatic and recurrent pancreatic cancer
Impact of second-line combination chemotherapy on post-progression survival in metastatic and recurrent pancreatic cancer
This study aimed to evaluate the efficacy of the second-line combination chemotherapy (CC) for patients with metastatic or...
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