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Exceptional Response to Pembrolizumab for Treatment of Metastatic Chemorefractory Endometrial Carcinoma in a Patient with Lynch Syndrome: A Case Report
Exceptional Response to Pembrolizumab for Treatment of Metastatic Chemorefractory Endometrial Carcinoma in a Patient with Lynch Syndrome: A Case Report
Advanced endometrial cancer is associated with poor outcomes and few treatment options exist. Recently, the US Federal Dru...
Case Report: Evolutionary Clinical-Radiological Features of a Diffuse Hemispheric Glioma, H3 G34 Mutant with Over 5 Years of Survival
Case Report: Evolutionary Clinical-Radiological Features of a Diffuse Hemispheric Glioma, H3 G34 Mutant with Over 5 Years of Survival
Diffuse hemispheric glioma (DHG), H3 G34 mutant was included in the 5th edition of the World Health Organization Classific...
Digital Gangrene and Antiphospholipid Syndrome in a Retinoblastoma Patient with Chromosome 13q Deletion: A Case Report
Digital Gangrene and Antiphospholipid Syndrome in a Retinoblastoma Patient with Chromosome 13q Deletion: A Case Report
A 19-month-old girl with Cornelia de Lange-like dysmorphic features presented with left eye leukocoria. She was diagnosed ...
23-Year-Old Male with Testis Cancer with Spontaneous Ruptured Teratocarcinoma and No History of Trauma: A Case Report
23-Year-Old Male with Testis Cancer with Spontaneous Ruptured Teratocarcinoma and No History of Trauma: A Case Report
Teratocarcinoma is one type of testis cancer that can be represented in the youth population and usually shows itself with...
A Metastatic Breast Tumor of an Appendiceal Signet Ring Cell Carcinoma
A Metastatic Breast Tumor of an Appendiceal Signet Ring Cell Carcinoma
A 54-year-old woman with pseudomyxoma peritonei from an appendiceal signet ring cell carcinoma was referred to our hospita...
Identification of a Novel NRG1 Fusion with Targeted Therapeutic Implications in Locally Advanced Pediatric Cholangiocarcinoma: A Case Report
Identification of a Novel NRG1 Fusion with Targeted Therapeutic Implications in Locally Advanced Pediatric Cholangiocarcinoma: A Case Report
Locally advanced cholangiocarcinoma has a poor prognosis, with long-term survival only for patients where complete surgica...
The Development of Lenvatinib-Induced Pancreatitis in a Patient with Metastatic Neuroendocrine Tumor: A Case Report
The Development of Lenvatinib-Induced Pancreatitis in a Patient with Metastatic Neuroendocrine Tumor: A Case Report
Lenvatinib is a tyrosine kinase inhibitor that is being used to treat neuroendocrine tumors based on the success shown in ...
Mistaken Metastasis: Radiation-Induced Rib Fracture Mimicking Malignancy on Computerized Tomography Case Report
Mistaken Metastasis: Radiation-Induced Rib Fracture Mimicking Malignancy on Computerized Tomography Case Report
A 62-year-old woman with a 40-pack-year smoking history and severe chronic obstructive pulmonary disease with early-stage ...
Successful Preoperative QUAD SHOT for Bulky Parotid Carcinoma: Potential Preoperative Ultra-Hypofractionated Radiotherapy for Conversion Surgery
Successful Preoperative QUAD SHOT for Bulky Parotid Carcinoma: Potential Preoperative Ultra-Hypofractionated Radiotherapy for Conversion Surgery
QUAD SHOT is an ultra-hypofractionated radiotherapy (RT) technique that prescribes 14.0–14.8 Gy over 2 days. Although this...
Zanubrutinib in the Maintenance Treatment of Elderly People with Primary Central Nervous System Lymphoma: A Report of 2 Cases
Zanubrutinib in the Maintenance Treatment of Elderly People with Primary Central Nervous System Lymphoma: A Report of 2 Cases
Primary central nervous system lymphoma (PCNSL) is a rare and aggressive extranodal non-Hodgkin lymphoma. The predominant ...
Durable Response to Pazopanib in a Patient with Fumarate Hydratase-Mutant Tubulocystic Renal Cell Carcinoma
Durable Response to Pazopanib in a Patient with Fumarate Hydratase-Mutant Tubulocystic Renal Cell Carcinoma
Tubulocystic carcinoma of the kidney (TC-RCC) is a rare renal tumor and has been recently included as a distinct entity in...
Circulating Tumor DNA Testing Overcomes Limitations of Comprehensive Genomic Profiling from Tumor Tissue
Circulating Tumor DNA Testing Overcomes Limitations of Comprehensive Genomic Profiling from Tumor Tissue
“Liquid biopsy” is an established technique for examining circulating tumor DNA (ctDNA) from a routine blood draw and dete...
Brain-Only Metastasis and 10-Year Survival after Curative Gastric Cancer Resection: A Case Report
Brain-Only Metastasis and 10-Year Survival after Curative Gastric Cancer Resection: A Case Report
Gastric cancer (GC) usually metastasizes to locoregional lymph nodes, the peritoneum causing ascites, or to the liver and ...
Unilateral Axillary Lymphadenopathy in Cancer Patients Post-COVID-19 Vaccination: Review and Case Series
Unilateral Axillary Lymphadenopathy in Cancer Patients Post-COVID-19 Vaccination: Review and Case Series
Novel coronavirus-19 (COVID-19) variants continue to spread worldwide with the development of highly transmissible strains...
Sotorasib as First-Line Treatment for Advanced KRAS G12C-Mutated Non-Small Cell Lung Carcinoma: A Case Report
Sotorasib as First-Line Treatment for Advanced KRAS G12C-Mutated Non-Small Cell Lung Carcinoma: A Case Report
Mutations in the <i>KRAS</i> gene are the most common gain-of-function mutations found in lung adenocarcinomas...
Pembrolizumab Induced Sclerosing Cholangitis: Why You Need a Liver Biopsy
Pembrolizumab Induced Sclerosing Cholangitis: Why You Need a Liver Biopsy
The advent of checkpoint inhibitor immunotherapy has rapidly changed the landscape of the management of cancers. However, ...
Recurrent Transient Asymptomatic Pulmonary Opacity with Long-Term Afatinib: A Case Report
Recurrent Transient Asymptomatic Pulmonary Opacity with Long-Term Afatinib: A Case Report
Afatinib is the second generation EGFR-TKI. Recently, transient asymptomatic pulmonary opacity (TAPO) was reported in EGFR...
Case Report of AdAPT-001-Mediated Sensitization to a Previously Failed Checkpoint Inhibitor in a Metastatic Chordoma Patient
Case Report of AdAPT-001-Mediated Sensitization to a Previously Failed Checkpoint Inhibitor in a Metastatic Chordoma Patient
Chordoma is a rare, but aggressive bone tumor with a high recurrence rate that primarily arises at the cranial and caudal ...
A Giant Paratesticular Liposarcoma: Case Report and Literature Review
A Giant Paratesticular Liposarcoma: Case Report and Literature Review
Liposarcoma of the spermatic cord (LSC) is a very rare disease. In literature, are reported less than 350 cases. Genitouri...
Intraplacental Choriocarcinoma in Twin Pregnancy Causing Fetomaternal Haemorrhage and Single Twin Demise: Case Report
Intraplacental Choriocarcinoma in Twin Pregnancy Causing Fetomaternal Haemorrhage and Single Twin Demise: Case Report
Gestational choriocarcinoma is a rare aggressive form of gestational trophoblastic neoplasia. In cases of intraplacental c...
Primary Ovarian Neuroendocrine Carcinoid Tumor Arising in a Mature Cystic Teratoma
Primary Ovarian Neuroendocrine Carcinoid Tumor Arising in a Mature Cystic Teratoma
Primary ovarian neuroendocrine carcinoid tumors are extremely rare. However, their clinical course is good, and hence, fer...
The Benefit of Telemonitoring in the Prevention of Septic Shock in a Patient with Aggressive Non-Hodgkin’s Lymphoma
The Benefit of Telemonitoring in the Prevention of Septic Shock in a Patient with Aggressive Non-Hodgkin’s Lymphoma
Telemonitoring is a great tool for vital signs monitoring in patients at high risk of severe life-threatening infections, ...
Treatment of Unresectable Cutaneous Squamous Cell Carcinoma with Cemiplimab in a Patient on Dialysis
Treatment of Unresectable Cutaneous Squamous Cell Carcinoma with Cemiplimab in a Patient on Dialysis
Program death-1 inhibitors, a class of immune-checkpoint inhibitors, are now the standard of care in a variety of cancer s...
Cushing’s Syndrome in Adenocarcinoma of Lung Responding to Osilodrostat
Cushing’s Syndrome in Adenocarcinoma of Lung Responding to Osilodrostat
Cushing’s syndrome (CS), secondary to paraneoplastic syndrome, is more commonly seen in small cell lung cancer but never b...
Rapid Dissemination followed by Spontaneous Regression of Metastatic Hepatocellular Carcinoma after Liver Radiofrequency Thermal Ablation: A Case Report with Correlative Immune Assay
Rapid Dissemination followed by Spontaneous Regression of Metastatic Hepatocellular Carcinoma after Liver Radiofrequency Thermal Ablation: A Case Report with Correlative Immune Assay
Rapid intrahepatic and distant metastasis of hepatocellular carcinoma (HCC) after locoregional treatment for early stage t...
Two Very Rare Cases of Metastatic Thymic Carcinoma with Sjogren’s Syndrome: A Case Series
Two Very Rare Cases of Metastatic Thymic Carcinoma with Sjogren’s Syndrome: A Case Series
Thymic tumours are rare thoracic malignancies with thymic carcinoma accounting for approximately 12% of all thymic tumours...
Androgen Deprivation Therapy for Intracranial Metastasis of a Salivary Duct Carcinoma: Case Report
Androgen Deprivation Therapy for Intracranial Metastasis of a Salivary Duct Carcinoma: Case Report
Salivary duct carcinoma (SDC) is a rare subtype of salivary cancers associated with androgen receptor and human epidermal ...
Capsule Endoscopy-Based Diagnosis of Lung Squamous Cell Carcinoma Associated with Abdominal Pain and Metastasis to Small Intestine: A Case Report
Capsule Endoscopy-Based Diagnosis of Lung Squamous Cell Carcinoma Associated with Abdominal Pain and Metastasis to Small Intestine: A Case Report
Gastrointestinal metastases of lung cancer are relatively uncommon, yet occur at a higher frequency than would be expected...
Primary Pleural Angiosarcoma Treated with Nivolumab and Ipilimumab: A Case Report
Primary Pleural Angiosarcoma Treated with Nivolumab and Ipilimumab: A Case Report
Primary pleural angiosarcoma (PPA) is a rare and clinically fatal pleural tumor originating from vascular endothelial cell...
A Case of Bilateral Synchronous Paratesticular Leiomyoma
A Case of Bilateral Synchronous Paratesticular Leiomyoma
Bilateral synchronous paratesticular leiomyoma (BSPL) is a rare tumor that originates from smooth muscle cells in the para...
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