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A Higher Risk of Liver Cancer in Alcoholic Fatty Liver Disease than in Non-Alcoholic Fatty Liver Disease: an Analysis of the TriNetX Dabatase
A Higher Risk of Liver Cancer in Alcoholic Fatty Liver Disease than in Non-Alcoholic Fatty Liver Disease: an Analysis of the TriNetX Dabatase
Both alcohol fatty liver disease (AFLD) and non-alcohol fatty liver disease (NAFLD) are established risk factors for liver...
Predicting Tumor Regrowth in Patients Undergoing Non-Operative Management after Total Neoadjuvant Therapy
Predicting Tumor Regrowth in Patients Undergoing Non-Operative Management after Total Neoadjuvant Therapy
Total neoadjuvant treatment (TNT) has become the standard of care for locally advanced rectal cancer (LARC), leading to in...
Recurrent Cytokine Release Syndrome in Metastatic Gastric Cancer on Nivolumab-FOLFOX: A Case Report and Mechanistic Review
Recurrent Cytokine Release Syndrome in Metastatic Gastric Cancer on Nivolumab-FOLFOX: A Case Report and Mechanistic Review
Cytokine release syndrome (CRS) is a hyperinflammatory condition most commonly observed following chimeric antigen recepto...
The Association Between Proton Pump Inhibitor Use and Gastroenteropancreatic Neuroendocrine Tumors: A Systematic Review
The Association Between Proton Pump Inhibitor Use and Gastroenteropancreatic Neuroendocrine Tumors: A Systematic Review
This systematic review evaluated the site-specific association between long-term use of proton pump inhibitors (PPIs) and ...
Exploring Recurrence Patterns of Esophageal Carcinoma Post-Curative Resection: a Comprehensive Study from a High-Volume Oncology Center in India
Exploring Recurrence Patterns of Esophageal Carcinoma Post-Curative Resection: a Comprehensive Study from a High-Volume Oncology Center in India
Carcinoma esophagus is an aggressive malignancy with high recurrence rates even after curative resection. This study aimed...
Resection Margin and Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma: Does Margin Status Matter in Nodal Disease?
Resection Margin and Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma: Does Margin Status Matter in Nodal Disease?
Lymph node metastasis (LNM) is a poor prognostic factor in intrahepatic cholangiocarcinoma (iCCA). However, the clinical b...
Association of Preoperative and Postoperative Serum Albumin Levels with Colorectal Cancer Outcomes: a Retrospective Cohort Study
Association of Preoperative and Postoperative Serum Albumin Levels with Colorectal Cancer Outcomes: a Retrospective Cohort Study
To elucidate the correlation between perioperative serum albumin concentrations and clinical outcomes in patients with col...
Misdiagnosis of Suspected Cancer in Pancreatoduodenectomy: A Systematic Review and Prevalence Mata-Analysis
Misdiagnosis of Suspected Cancer in Pancreatoduodenectomy: A Systematic Review and Prevalence Mata-Analysis
Differentiating between pancreatic cancer (PC) and benign pancreatic lesions is challenging, leading to misdiagnosis and u...
Impact of Abdominal Aortic Calcification on Long-Term Outcome after Gastric Cancer Surgery: a Retrospective Study
Impact of Abdominal Aortic Calcification on Long-Term Outcome after Gastric Cancer Surgery: a Retrospective Study
This study examined the impact of abdominal aortic calcification, a known risk factor for cardiovascular disease, on the p...
Clinicopathological Factors and Nomogram Construction for Lymph Node Metastasis in Early-Onset Colorectal Cancer
Clinicopathological Factors and Nomogram Construction for Lymph Node Metastasis in Early-Onset Colorectal Cancer
Colorectal cancer (CRC) is the most prevalent malignant tumor of the digestive system globally, ranking third in incidence...
From Detection to Delay: Real-World Gaps in Post-Cologuard Colonoscopy Adherence
From Detection to Delay: Real-World Gaps in Post-Cologuard Colonoscopy Adherence
Colorectal cancer remains a leading cause of cancer deaths, highlighting the need for early detection. Cologuard®, a ...
Association of Spirometric Lung Age with Survival Outcomes in Elderly Patients Undergoing Radical Surgery for Gastric Cancer
Association of Spirometric Lung Age with Survival Outcomes in Elderly Patients Undergoing Radical Surgery for Gastric Cancer
The proportion of elderly patients among those diagnosed with gastric cancer (GC) is increasing worldwide. Given that phys...
Proton Pump Inhibitors Attenuate the Effectiveness of Nivolumab Monotherapy in Patients with Advanced Gastric Cancer: A Retrospective Study
Proton Pump Inhibitors Attenuate the Effectiveness of Nivolumab Monotherapy in Patients with Advanced Gastric Cancer: A Retrospective Study
This study aimed to investigate the effects of concomitant proton pump inhibitor (PPI) use on the effectiveness of nivolum...
Local Recurrence Rates in Locally Advanced Rectal Cancer Are Higher with KRAS Codon 13 Mutations
Local Recurrence Rates in Locally Advanced Rectal Cancer Are Higher with KRAS Codon 13 Mutations
Despite advances in oncology regimens and standardization of technical approaches such as total mesorectal excision (TME),...
Radioembolization in Hepatocellular Carcinoma: Indications and Outcomes
Radioembolization in Hepatocellular Carcinoma: Indications and Outcomes
Hepatocellular carcinoma (HCC) continues to rank among the most common causes of cancer-associated deaths, especially sinc...
The Dynamic Changes of Circulating Myeloid-Derived Suppressor Cells (MDSCs) Subsets in Colorectal Cancer Patients Undergoing Oxaliplatin-Based Chemotherapy
The Dynamic Changes of Circulating Myeloid-Derived Suppressor Cells (MDSCs) Subsets in Colorectal Cancer Patients Undergoing Oxaliplatin-Based Chemotherapy
Increased level of circulating myeloid -derived suppressor cells (MDSCs) in colorectal cancer (CRC) patients has been asso...
A Novel Diagnostic Model of Biomarkers in the Washing Fluid Obtained by EUS-FNA in Pancreatic Cancer
A Novel Diagnostic Model of Biomarkers in the Washing Fluid Obtained by EUS-FNA in Pancreatic Cancer
Currently, there are no biomarkers with high accuracy in the detection of pancreatic cancer. This article aims to evaluate...
Combined Chemotherapy-Immunotherapy for Advanced Biliary Tract Cancer (BTC): A Clinical, Genomic, and Biomarker Analysis
Combined Chemotherapy-Immunotherapy for Advanced Biliary Tract Cancer (BTC): A Clinical, Genomic, and Biomarker Analysis
Biliary tract cancer (BTC) represents a heterogeneous disease spectrum associated with an unfavorable prognosis. A combina...
Diagnostic Yield of Combining CT Colonoscopy and Endoscopy to Investigate Colorectal Cancer
Diagnostic Yield of Combining CT Colonoscopy and Endoscopy to Investigate Colorectal Cancer
The number of urgent referrals for suspected colorectal cancer in the NHS is constantly on the rise placing significant st...
Incidental Gallbladder Cancer: A Comprehensive Review
Incidental Gallbladder Cancer: A Comprehensive Review
Patients undergoing cholecystectomy for a presumed benign disease may present with histopathology report revealing carcino...
FGFR as a Predictive Marker for Targeted Therapy in Gastrointestinal Malignancies: A Systematic Review
FGFR as a Predictive Marker for Targeted Therapy in Gastrointestinal Malignancies: A Systematic Review
Gastrointestinal (GI) cancers constitute approximately 25% of cancers worldwide. The fibroblast growth factor receptor (FG...
Regulatory T Cell Infiltration-Driven Single-Cell Transcriptomic Analysis Identifies SAP18 as a Prognostic Marker for Esophageal Squamous Cell Carcinoma
Regulatory T Cell Infiltration-Driven Single-Cell Transcriptomic Analysis Identifies SAP18 as a Prognostic Marker for Esophageal Squamous Cell Carcinoma
Advanced esophageal squamous cell carcinoma (ESCC) is characterized by molecular heterogeneity and distinct patterns of im...
A Case Study on Complete Pathological Response in Advanced Rectal Cancer Patient with Oxaliplatin-based Chemotherapy without Cumulative Neurotoxicity
A Case Study on Complete Pathological Response in Advanced Rectal Cancer Patient with Oxaliplatin-based Chemotherapy without Cumulative Neurotoxicity
The pathological response in rectal cancer treatment provides insight into the molecular mechanisms, including genetic alt...
Supportive Care Needs and Related Interventions in Patients with Pancreatic Cancer and Their Informal Caregivers: A Scoping Review
Supportive Care Needs and Related Interventions in Patients with Pancreatic Cancer and Their Informal Caregivers: A Scoping Review
This scoping review aims to provide a comprehensive literature review regarding supportive care needs and related interven...
Surgical Resection Versus Microwave Ablation for Colorectal Liver Oligometastases: A Multicenter Cohort Study of 1027 Patients
Surgical Resection Versus Microwave Ablation for Colorectal Liver Oligometastases: A Multicenter Cohort Study of 1027 Patients
The choice between surgical resection (SR) and microwave ablation (MWA) as first-line treatments that prolong survival dur...
Identification of Novel Protein Biomarkers for Intrahepatic Cholangiocarcinoma by Integrating Human Plasma Proteome with Genome
Identification of Novel Protein Biomarkers for Intrahepatic Cholangiocarcinoma by Integrating Human Plasma Proteome with Genome
The proteome serves as a key source for the discovery of therapeutic targets. This study utilized proteome-wide Mendelian ...
Effects of Palliative Esophageal External Beam Radiation Therapy in Patients with Stent for Esophageal Cancer: A Retrospective Cohort Study
Effects of Palliative Esophageal External Beam Radiation Therapy in Patients with Stent for Esophageal Cancer: A Retrospective Cohort Study
Self-expandable metallic stents (SEMS) provide immediate but nondurable dysphagia relief in esophageal cancer, while exter...
Homologous Recombination Deficiency Is Associated with Shorter Survival in Colorectal Cancer Patients
Homologous Recombination Deficiency Is Associated with Shorter Survival in Colorectal Cancer Patients
Colorectal cancer (CRC) patients benefit more from immune checkpoint inhibitor therapy, but they only account for around 1...
Immune-Based Therapies in Pancreatic Cancer: a Systematic Review of Ongoing Clinical Trials (2020–2022)
Immune-Based Therapies in Pancreatic Cancer: a Systematic Review of Ongoing Clinical Trials (2020–2022)
Immune-based treatment strategies have emerged across solid organ malignancies largely with the development of immune chec...
Pancreatic Acinar Cell Carcinoma: Demographics, Treatment, and Survival Outcomes, A Retrospective Population-Based Study
Pancreatic Acinar Cell Carcinoma: Demographics, Treatment, and Survival Outcomes, A Retrospective Population-Based Study
Pancreatic acinar cell carcinoma accounts for 1–2% of pancreatic tumors, with increasing frequency in recent years, ...
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