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Effect of the porosity of the palladium shell in Au-core Pd-shell bimetallic nanoparticles for the radiosensitizing properties in simulated anticancer proton radiotherapy
The combination of radiotherapy and metallic nanoparticles (NPs) turns out to be a promising option for cancer treatment. ...
Optimised amine density via plasma treatment for covalent immobilisation of AMPs to promote osteoblasts and enhance antimicrobial activity
Bacterial infections remain a leading cause of failure in biomedical implants. To mitigate this, surface modification stra...
Gambogic acid and an NIR organic photothermal agent co-assembled nanoplatform to ignite immunogenic cell death / HSP90 suppression / ferroptosis for enhanced tumor mild-photothermal therapy
Photothermal therapy (PTT) has garnered significant attention as a noninvasive strategy for cancer treatment, primarily du...
Study on periodontal tissue regeneration induced by MXene-loaded electrospun oriented PCL fiber membranes
Periodontitis is a chronic disease of the periodontal tissues caused by the accumulation of bacteria in the periodontal ti...
Development of liposomal nanocarriers for granulosa cell interaction: Integrating physicochemical characterization with gene expression analysis
Liposomes (LPs) are nanoscale vesicles composed of one or more phospholipid bilayers that self-assemble in aqueous environ...
CD44-targeted NLCs improve trans-resveratrol in vitro cellular uptake and cytotoxicity in high-grade glioma cells.
High-grade gliomas (HGGs; WHO grades III and IV) encompass a heterogeneous group of malignant brain tumors characterized b...
Polynorepinephrine nanoagent enables targeted mitochondrial delivery for enhanced tumor therapy through ferroptosis
As a major cause of human mortality, cancer remains an immense challenge for which discovering a definitive cure is still ...
Rabbit monoclonal antibodies: Synergistic innovation and breakthrough based on B-cell development mechanism and single B-cell technology
The rabbit (Oryctolagus cuniculus) is an important species worldwide used as a laboratory animal and model for larger spec...
Tumor exosome-based drug delivery system targeting ferroptosis and apoptosis for glioblastoma therapy
Glioblastoma (GBM) is the deadliest brain tumor with a high mortality rate [1], [2], [3]. Even though adopting multimodal ...
Decoding fibrotic encapsulation in plastic surgery implants: From biological mechanisms to precision interventions frontiers
Plastic and reconstructive surgery relies heavily on implant-based devices, particularly implants used in breast augmentat...
Decoupling surface stiffness from surface chemistry: Impact on bacterial adhesion and retention under shear conditions
Bacterial colonization of abiotic surfaces is a critical initial step in biofilm formation, particularly in medical contex...
Multistage oral astaxanthin targeted delivery system: Increasing serotonin levels with a dual therapeutic effect for alleviating inflammatory bowel disease and psychiatric disorders
Inflammatory bowel disease (IBD) can induce persistent inflammation in the intestines, which can substantially diminish th...
Endometrial regenerative cell exosome-derived Sirtuin 6 alleviates ulcerative colitis by remodeling macrophage polarization
Ulcerative colitis (UC) and Crohn's disease (CD) are the two most common forms of inflammatory bowel disease (IBD), which ...
Modulating the biological response in vitro through hydrofluoric acid surface etching of ceria-stabilized zirconia/alumina/strontium hexa-aluminate composites
Dentistry has evolved astonishingly since the advent of osseointegrated dental implants. Owing to the convenient mechanica...
Carbon dots based nanozymes: Synthesis, structure, catalytic mechanisms and applications
Gao et al. [1] discovered that Fe3O4 nanoparticles exhibited peroxidase (POD)-like activity, overturning the traditional b...
Ultrasound molecular imaging of antibody-mediated rejection with CD16a-targeted probes in a complement-independent pathway
BackgroundAntibody-mediated rejection (AMR) is a critical cause of graft dysfunction after heart transplantation. The diag...
A composite jellyfish collagen hydrogel with skin-matched modulus enables programmed and high-quality wound healing
Skin is the largest immune organ of body, with multiple and critical functions such as signal transduction, temperature re...
Oleanolic acid-taxifolin self-assembled nanoparticles for effective treatment of S. aureus infections by inhibiting its internalization and reproduction
Staphylococcus aureus (S. aureus) is the typical opportunistic bacterium of numerous kinds of animal species, including hu...
Fe-Mn-IGF-AMD nanoparticles in accurate detection and treatment of liver cirrhosis via regulating relaxation coefficients and attenuating hepatocyte senescence
Organ fibrosis is a hallmark of chronic inflammatory disease and accounts for 45 % of deaths in the industrialized world [...
A dual-multivalent aptamer-DNA nanocarriers for enhancing antitumor effects of photodynamic-chemotherapy combined therapy
Cancer has become the first killer to human life and health in the 21 st century [1]. Photodynamic therapy (PDT) has displ...
Recent progress in alginate-based nanocomposites for bone tissue engineering applications
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Cobalt carbonate nanorods enhance chemotherapy via neutralization of acidic tumor microenvironment and generation of carbonate radical anions for necrosis
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Advances in nanoplatform-based multimodal combination therapy activating STING pathway for enhanced anti-tumor immunotherapy
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Tannic acid coating modification of polypropylene providing pH-responsive antibacterial and anti-inflammatory properties applicable to ostomy patches
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Construction of a methacrylated gelatine composite hydrogel based on tachyplesin II and its application in the repair of infected wounds
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Polycaprolactone (PCL)‐Gelatin Electrospun Meshes for Accelerated Gastric Wound Healing
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Hydrogels of diet-derived electron donors restore epithelial hypoxia and reduce iNOS synthesis to inhibit inflammation-induced overgrowth of facultatively anaerobic bacteria for gut homeostasis
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GRP94 mediates blood-brain barrier permeation and substantia nigra-specific drug distribution in Parkinson’s disease
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Inhalable lipid-based nanocarriers covered by polydopamine for effective mucus penetration and pulmonary retention
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Formulation and heat stability of self-assembled O/W food-grade microemulsions formulated with bile salts or tween 80 as surfactants
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