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Triptolide impacts CSF1R expression and reprograms the suppressive function of myeloid-derived suppressor cells via targeting the ER stress pathway
Hepatocellular carcinoma (HCC) is one of the most prevalent types of cancer and is the third leading cause of cancer-relat...
IRF4 exacerbates pulmonary inflammation in bronchopulmonary dysplasia mice model by regulating macrophage polarization and phagocytosis
Bronchopulmonary dysplasia (BPD) is a severe respiratory disorder that markedly impacts the survival [1] and long-term out...
Distinct cytokine signature in juvenile dermatomyositis: linking myositis-specific antibodies and clinical manifestations
Juvenile dermatomyositis (JDM) is an autoimmune myositis that primarily causes inflammation of the skin and skeletal muscl...
Combining single-cell analysis and Mendelian randomization to elucidate the molecular mechanisms of fibronectin-related genes in multiple sclerosis
ANOVAanalysis of varianceCD3ζT cell receptor T3 zeta chainCNScentral nervous systemDEGsdifferentially expressed genesEAEex...
Dissecting the effect of blood colony-stimulating factors and receptors on Alzheimer's disease: the role of myeloid traits and inflammation
Alzheimer's Disease (AD) is the most common neurodegenerative disorder, characterized by memory loss and cognitive impairm...
Association of toll-like receptors polymorphisms with atopy and asthma symptoms in Latin American children
The prevalence of allergic diseases and asthma is increasing worldwide and according to the Global Initiative for Asthma (...
Dysregulated inflammatory cytokines in MSM living with HIV who exhibited suboptimal immune reconstitution despite antiretroviral therapy (ART)
The advent of antiretroviral therapy (ART) has fundamentally transformed the clinical course of HIV infection, transformin...
The role of cytokines in immune cell-mediated multiple myeloma and the identification of therapeutic targets
Multiple Myeloma (MM) is a malignant hematological disease originating from plasma cells, characterized by the uncontrolle...
Ontogeny of plasma cytokine and chemokine concentrations across the first four months of human life in a Papua new Guinean cohort
The immune system in early-life is shaped by both intrinsic trajectories and environmental influences, reflecting a dynami...
FOXC1 ameliorates the disease progression of psoriasis through transcriptional upregulation of SOCS3
Psoriasis is a chronic and common immune-mediated skin disease [1,2] that occurs worldwide and can affect the skin, joints...
Drug repurposing for cytokine storm: baricitinib, ciclesonide, and acalabrutinib modulate cytokine release in a translational in vitro lymphoblastoid cell line model
Cytokine storm, a life-threatening hyperinflammatory response seen in severe infections like COVID-19, autoimmune diseases...
Natural killer cell-related gene signature predicts immune cell infiltration and improved survival in bladder cancer
Bladder cancer (BC) is one of the most common malignancies of the genitourinary system, ranking fourth in incidence among ...
TREM-1: A potential prognostic marker in newborns with late-onset sepsis
Neonatal sepsis is a prevalent condition among newborns (NB), particularly those born preterm, yet a consensus definition ...
Corrigendum to “Risk factors associated with short-term mortality in patients with candidemia and the predictive value of serum cytokine level” [Cytokine 185 (2025) 156803]
Volume 197, January 2026, 157077Author links open overlay panelXueqing Fang a c, Congling Su b c, Yan Luo d, Kai Pan e, Ji...
Promoter variants of tumor necrosis factor-alpha (G-308 a: rs1800629 and C-857 T:rs1799724) are linked to type 1 diabetes: A meta-analysis and trial sequential analysis
Type 1 diabetes (T1D) is a long-term autoimmune condition characterised by the destruction of insulin-producing beta cells...
SMAD signaling in cancer: integrative roles in tumor progression, immune evasion, and therapeutic resistance
Cancer progression is orchestrated by a series of signaling pathways that altogether regulate cell plasticity, immune evas...
Systemic immune inflammation index, systemic inflammatory response index and pan-immune inflammation value in the prediction of idiopathic late-onset fetal growth restriction
Fetal growth restriction (FGR) occurs in about 10 % of pregnancies and is characterized by fetal growth below the expected...
Macrophage USP14 suppresses Wnt/β-catenin signaling via NLK deubiquitination to enhance immune response
Macrophages are key immune effectors that shape host immunity and drive the initiation and progression of numerous disease...
IL-35 alleviates ferroptosis in macrophage by activating the NRF2/GPX4 pathway to improve sepsis-induced ARDS
Acute respiratory distress syndrome (ARDS) is defined as an acute progressive respiratory failure caused by a variety of f...
Dynamic changes in the frequency of classical CD14HighCD16- and inflammatory CD14++CD16+ monocyte subsets in patients with advanced liver fibrosis
Hepatitis C virus (HCV) infection is an important public health problem. According to estimates, the prevalence of hepatit...
Effects of botulinum toxin type a on nucleotide binding oligomerization domain-like receptor 3 inflammasome in trigeminal ganglion of a rat migraine model
In the clinic, migraine is a debilitating and common neurological condition and a primary central nervous system dysfuncti...
Shedding new light on BACE1-mediated modulation of IL-6 signaling: Implications for neural activity and synaptic plasticity in mice
Interleukin-6 (IL-6) is a pleiotropic cytokine that plays a pivotal role in various physiological and pathological process...
The synergistic effects of prostaglandin and IL-1β on myometrial and cervical stromal cells at the onset of labor
Labor is a complex physiological process. As pregnancy reaches its culmination, the myometrium undergoes a transformation ...
Exploring the genetic association between inflammatory cytokines and primary ovarian insufficiency: A Mendelian randomization study
Multiple genome-wide association study (GWAS) have been carried out recently, that have enhanced our awareness of the gene...
Novel genetic associations with childhood adipocytokines in Indian adolescents
Adipose tissue communicates with other organs by secreting endocrine molecules known as adipocytokines, such as leptin, ad...
Hydrogen combined with needle-embedding therapy alleviates traumatic brain injury by inhibiting NLRP3 inflammasome activation via STING signaling pathway
Traumatic brain injury (TBI) is one of the most frequent causes of mortality and disability worldwide, which has become a ...
Resveratrol interrupts Wnt/β-catenin signalling in cervical cancer by activating ten-eleven translocation 5-methylcytosine dioxygenase 1
Cervical Cancer (CC) is a significant health concern, and over 99.7 % of CC cases are attributed to high-risk papillomavir...
ADAM17/ACE2 interaction mediates cadmium-induced brain damage and neuroinflammation in Wistar rats
Heavy metal toxicity is a common health problem increasing globally owing to unavoidable environmental and occupational ex...
Corrigendum to “An update on the association between metabolic syndrome and osteoarthritis and on the potential role of leptin in osteoarthritis” [Cytokine 129 (2020) 155043]
Volume 190, June 2025, 156923Author links open overlay panelYu-Hang Gao a, Cheng-Wu Zhao b, Bo Liu c, Ning Dong d, Lu Ding...
Cytokine immune profiles among COVID 19 patients with different disease severities seeking treatment at Moi teaching and referral hospital, Kenya
The Coronavirus Disease 2019 (COVID-19) pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-...
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