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Ginkgetin alleviates UV-induced skin photoaging by reducing oxidative stress and promoting DNA repair via AKT-mediated homologous recombination repair
Skin photoaging caused by accumulated UV radiation manifests as uneven pigmentation, telangiectasia, rough texture, wrinkl...
Protective effects of okra (Abelmoschus esculentus (L.) Moench) seed extract against acute and chronic UV-induced skin damage, implicating PLD-associated lipid signaling
Occupying the greatest surface area of the human organism, the skin acts as a physical barrier to environmental insults wh...
Development of a self-assembling aggregation-induced emission nanoprobe for targeted therapy and real-time imaging in non-small cell lung cancer
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality worldwide, characterized by poor pr...
Antimicrobial effect and safety of 228 nm far-UVC light-emitting diodes
This is the first study to evaluate the antimicrobial effect and safety of a newly developed light-emitting diode (LED) th...
New conjugates of natural chlorins with doxorubicin featuring controlled release for combined photodynamic and chemotherapeutic treatment
Cancer is a disease of significant social importance whose treatment requires multidisciplinary expertise. Its distinguish...
Use of 940 nm diode laser irradiation on conventional and cerium oxide-reinforced orthodontic adhesive before light-activated polymerization on the degree of conversion, and adhesive strength of orthodontic brackets. A scanning Electron microscope assessment
In contemporary orthodontic practice, achieving consistent bond strength between brackets and tooth surfaces is crucial fo...
Near-infrared photobiomodulation can alleviate chemotherapy-induced peripheral neuropathy-associated sensory abnormalities
Cancer continues to be a significant global public health concern, ranking as the second leading cause of death in China [...
Development of CeO₂/Fe₂O₃ nanocomposite for photocatalytic and biological studies
The rapid evolution of nanotechnology in recent years has been particularly in the development of nanoparticles that exhib...
Inactivation kinetics for plasmonic photothermal based eradication of ESKAPE and Candida albicans pathogens
ESKAPE pathogens- comprising Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, ...
Glycosylation and ESIPT synergistically regulate the antioxidant activity of flavonoids
Flavonoids with photoluminescence, a class of organic compounds, exhibit diverse and significant biomedical properties, in...
Red/far-red light optogenetics: technological principles and biomedical applications
Optogenetics, an interdisciplinary field combining optical engineering and genetic principles, is a cutting-edge biotechno...
Contact-dependent regulation of UV-B/C-induced cell fate by neighboring intact cells
UV light damages macromolecules, such as DNA [1] and proteins [2], leading to a range of cellular phenotypes, including ox...
Effectiveness of photodynamic therapy against Escherichia coli: Influence of light dose fractionation in the presence of porphyrins, methylene blue and zinc phthalocyanine disulfonate
Excessive use of antibiotics contributes to the development of multidrug-resistant microorganisms, making bacterial infect...
Ultra-weak photon emission during ischemia–reperfusion: Characterizing response dynamics and reproducibility
ObjectiveUltra-weak Photon Emission (UPE) is thought to represent chemiluminescence from oxidative metabolic processes. Th...
Photobiomodulation therapy enhances pericyte coverage during skin regeneration in a murine diabetic model
Photobiomodulation (PBMT) speeds up wound healing, partly by attracting pericytes. However, its specific mechanisms in a d...
Filamentous fungi as eco-friendly precursors for the synthesis of luminescent green-emitting carbon dots
This study reports the synthesis and characterization of fungal carbon dots (F-CDs) derived from filamentous microfungi be...
Zr-modified TiO₂ nanocomposites with enhanced visible-light photocatalytic and photobiological performance
A broad class of materials with distinctive physicochemical characteristics, metal oxides are extremely beneficial in a wi...
Single-cell and spatial transcriptomics identify PGK1-sensitized hypoxia macrophages as a therapeutic target to overcome PDT resistance in glioma
Glioma represents the most prevalent and aggressive primary intracranial malignancy in adults, characterized by infiltrati...
Structural insights into photo-state-specific binding of affibody Aff6 to the photosensory core module of DrBphP
Light-inducible protein heterodimerization systems, which are based on genetically encoded light-sensitive proteins and th...
Subcellular photoprotection through precision nutraceuticals: Divergent actions of rutin and punicalagin on redox and mitochondrial homeostasis in human dermal fibroblasts
Excessive ultraviolet A (UVA) exposure is a major environmental factor contributing to skin photoaging and oxidative damag...
Synthesis and photophysical properties of a chlorin conjugate with a photoswitchable local anesthetic
Currently, oncology treatment widely involves surgery, chemotherapy, and radiation therapy. However, all these approaches ...
Prolonged DNA damage at suberythemal UV dose – Dependency on skin type and age
Ultraviolet radiation (UVR) is the primary risk factor for skin cancer, inducing DNA damage such as cyclobutane pyrimidine...
Photobiomodulation mitigates DHT-induced apoptosis in dermal papilla cells via mitochondrial rescue and Wnt/TGF-β/BMP signaling modulation
Alopecia (hair loss), particularly androgenetic alopecia (AGA) [1], is a widespread condition that poses significant chall...
Phthalocyanine-based nanosensitizers for enhanced sonodynamic therapy activity of hypoxic tumor with dual apoptosis/ferroptosis pathways
Sonodynamic therapy (SDT) is an emerging and promising cancer treatment modality, which employs ultrasound (US) to stimula...
Enhanced photodynamic therapy with riboflavin@ dual minerals doped hydroxyapatite nanoparticles: A promising in vitro approach for bladder cancer
High incidence and death rates define bladder cancer, a major worldwide health burden. Ranked ninth most common cancer and...
Photobiomodulation mediates endoplasmic reticulum-mitochondria contact and ameliorates lipotoxicity in MASLD via Mfn2 upregulation
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAF...
A hydroxyl coumarin-chalcone-based fluorescent probe for sensing copper ions in plant and living cells
Heavy metal and transition metal ions are widely present in the natural world and have significant implications for human ...
Natural-synthetic hybrid nanoparticles: Polydopamine-Phycocyanin composites for enhanced antibacterial phototherapy against bacterial pathogens
Since 3.5 billion years ago, bacteria have continuously evolved to survive in harsh conditions. With the discovery of peni...
Femtosecond laser-induced myocardial incision: Preclinical study towards new tools for precision cardiac surgery
Femtosecond laser technology has emerged as an efficient therapeutic tool, demonstrating significant potential across vari...
Therapeutic potential of near-infrared polychromatic light in hyperglycemic human cell models: Toward improved diabetic wound healing
Diabetes is a metabolic disorder characterized by insulin resistance or impaired insulin secretion. Chronic hyperglycemia ...
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