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Targeted stabilization of astrocytic Cx43 gap junctions reverses depression-like behaviors via dual restoration of syncytial networks and glutamatergic homeostasis

Neurochemistry International

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Let-7a-5p targets MAP3K1 to regulate the MAPK signaling pathway in a depression model

Neurochemistry International

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Electronic cigarette vapor exposure modifies stroke-induced transcriptional and microglial responses in a sex-dependent manner

Neurochemistry International

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Lrp10 insufficiency upregulates mRNA and protein of neurotoxic α-synuclein and causes degeneration of substantia nigra dopaminergic neurons in heterozygous or homozygous Lrp10 knockout mice

Neurochemistry International

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TDP-43 expression in the cytoplasm leads to early synaptic and mitochondrial abnormalities in an inducible mouse model of ALS/FTD

Neurochemistry International

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Soy lysolecithin attenuates hypertension and behavioral impairments in mice fed a high-salt diet through receptor-specific regulation of prostaglandin signaling and arachidonic acid-derived prostaglandin production

Neurochemistry International

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Paeonol ameliorates scopolamine- and β-amyloid 1–42 oligomer-induced cognitive impairments through modulation of the TGR5–PKA–cAMP response element-binding–brain-derived neurotrophic factor pathway and inhibition of acetylcholinesterase

Neurochemistry International

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Nature-origin phthalides for Parkinson's disease drug development

Neurochemistry International

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The impact of long-term feeding with curcuminoids phospholipids enriched diet on disease progression of fALS

Neurochemistry International

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Disturbed lipid metabolism in microglia after cerebral ischemia-reperfusion

Neurochemistry International

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An emerging therapeutic strategy for major depressive disorder: targeting the protein-protein interactions

Neurochemistry International

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Regular light-intensity exercise accelerates contextual fear extinction with reduced dorsal CA3 activation in male rats

Neurochemistry International

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Effects of chemogenetic regulation of CaMKⅡα positive neurons in the ventral hippocampus on working memory impairment in the hemiparkinsonian rat

Neurochemistry International

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Iron overload inhibits neuronal extracellular vesicles secretion via SNARE dysfunction

Neurochemistry International

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Epigenetic mechanisms of (electro)acupuncture in acute neuroprotection and rehabilitation of stroke

Neurochemistry International

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Phytochemical engineered quantum dots as potential therapy to counter alpha synuclein aggregation in Parkinson's disease

Neurochemistry International

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Neuro-nutraceutical role of Indian spices, spice mixes and their bio-actives: An update

Neurochemistry International

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The antidepressant venlafaxine induces upregulation of miR-92 and histological alterations in a chicken embryo model

Antidepressants are commonly prescribed for treating anxiety disorders and depression, including pregnant patients. These ...

Neurochemistry International

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Neuronutritional enhancement of antioxidant defense system through Nrf2/HO1/NQO1 axis in fibromyalgia

Fibromyalgia (FM) is a disorder characterized by chronic widespread musculoskeletal pain, and it is often accompanied by f...

Neurochemistry International

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Constant light exposure promotes pathogenic tau hyperphosphorylation and phenotypic manifestations in Drosophila disease models

Artificial light-mediated sleep disruption during night in urbanised establishments has emerged as a man-made hazard for i...

Neurochemistry International

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Spinal p38 MAPK/PGC-1α/SIRT3 signaling pathway mediates remifentanil-induced hyperalgesia in rats via ROS release and NR2B activation

Remifentanil, as a novel opioid drug of the 21st century, offers significant advantages including rapid onset, an ultrasho...

Neurochemistry International

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SPP1 expression after spinal cord compression injury and its effects on glial cell activation

Spinal cord injury (SCI) often caused permanent functional impairment, significantly burdening families and society (Yuan ...

Neurochemistry International

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Genetic and epigenetic architectures of stroke: Insights from GWAS to precision medicine

Stroke remains a leading cause of death and disability, driven by complex interactions among genetic, epigenetic, and envi...

Neurochemistry International

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Manganese stimulates ferroptosis to trigger neurotoxicity in mice and HT22 cells: the role of NCOA4-mediated ferritinophagy

Manganese (Mn) is a vital trace element that plays a significant role in several critical physiological processes within t...

Neurochemistry International

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Functional effects of heavy metal exposures on N6-methyladenosine (m6A) methylation and other Epitranscriptomic modifications in the central nervous system

This manuscript reviews recent work that may begin to shed light on how heavy metal exposures may affect m6A methylation, ...

Neurochemistry International

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Differences in presynaptic hippocampal GABAergic terminals at the early stage of life in female and male mice: effect of an acute early inflammatory challenge

GABA dictates the efficiency of synaptic connection, influencing its developmental complexity, but its role is tuned by de...

Neurochemistry International

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The potential of mulberry (Morus alba L.) leaf extract against pro-aggregant tau-mediated inflammation and mitochondrial dysfunction

Human Tau has been implicated in the pathogenesis of neurodegenerative tauopathies including Alzheimer's disease (AD), fro...

Neurochemistry International

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