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AlphaFold3-guided optimization of a photoactivatable endonuclease for top-down genome engineering
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110762Author links open overlay panel, , , Recent adva...
Compartmentalized thymidine phosphorylation by mitochondrial nucleotide kinases TK2 and CMPK2
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110733Author links open overlay panel, , , , , , Deoxy...
The growth factor FGF21 maintains neuromuscular junction through histone deacetylase HDAC4 in denervation-induced skeletal muscle atrophy
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110756Author links open overlay panel, , , , , , , , S...
Molecular basis of IFN-γ–induced STAT3 phosphorylation stimulated by Sendai virus C protein
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110744Author links open overlay panel, , , , , , , , ,...
UBE2O, a host ubiquitin-conjugating enzyme, is a key regulator of hepatitis B virus maturation and egress
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110750Author links open overlay panel, , , , , , , , A...
NR4A1 is a HIF-dependent repressor of SLC30A10 transcription that controls manganese homeostasis
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110707Author links open overlay panel, , , , , The pri...
Rules of engagement: Determinants of chemokine receptor activation and selectivity by CCL27 and CCL28
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110736Author links open overlay panel, , , , , , , The...
A shared basis for nutrient limitation response in cyanobacteria
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110765Author links open overlay panel, , , , Cyanobact...
The ubiquitin ligase Nedd4-2 promotes localization of DNMBP/Tuba to P-bodies under hyperosmotic stress
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110738Author links open overlay panel, , , , The ubiqu...
Intrinsically disordered cytoplasmic tail in netrin receptor DCC binds the large ribosomal subunit to inhibit translation
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110741Author links open overlay panel, , , , , , Trans...
Systematic analysis of the RGS2 degron reveals characteristics of substrate recognition by the F-box protein FBXO44
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110757Author links open overlay panel, , , , , Regulat...
Structural basis for L-isoaspartyl-containing protein recognition by the human PCMTD1 cullin-RING E3 ubiquitin ligase
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110735Author links open overlay panel, , , , , , , , ,...
Deciphering mutational effects on inducible NO synthase conformational dynamics via quantitative cross-linking mass spectrometry and AlphaFold2 subsampling
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110673Author links open overlay panel, , , , Mammalian...
S2Tag, a novel affinity tag for the capture and immobilization of coiled-coil proteins: Application to the study of human β-cardiac myosin
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110776Author links open overlay panel, , , , Single-mo...
Missense mutations in intrinsically disordered protein regions link pathogenicity and phase separation
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110773Author links open overlay panel, , , The impact ...
The cytoplasmic domains of the CNNM family of transmembrane proteins modulate the ion channel-kinase TRPM7
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110720Author links open overlay panel, , , , , , , , ,...
An amino acid transporter in the small intestine mediates basolateral efflux of plant-derived nicotianamine iron complexes
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110731Author links open overlay panel, , , , , , , , N...
Human sperm KSper is physiologically activated by intracellular pH alkalization and CatSper-mediated Ca2+ signaling
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110752Author links open overlay panel, , , , , The hyp...
Differential modulation of polycystin-2 gain-of-function channels by cysteine-reactive compounds, amphiphilic substances, and S4-S5 linker mutations
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110766Author links open overlay panel, , , , Polycysti...
Correction: Arg-73 of the RNA endonuclease MazF in Salmonella enterica subsp. arizonae contributes to guanine and uracil recognition in the cleavage sequence
Journal of Biological ChemistryVolume 301, Issue 11, November 2025, 110767Author links open overlay panelTakuma Okabe, Rie...
Structure-function studies of a nucleoplasmin isoform from Plasmodium falciparum
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Substrate recognition in Bacillus anthracis sortase B beyond its canonical pentapeptide binding motif and use in sortase-mediated ligation
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Cardioprotective effect of genetic ablation of the G-protein coupled receptor kinase GRK2 in adult pancreatic β-cells during high fat diet
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Insights into the transcriptional regulation of CD22 in B cell chronic lymphocytic leukemia
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Human tau promotes Warburg effect-like glycolytic metabolism under acute hyperglycemia conditions
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Rational Design, Synthesis, and Evaluation of Novel Polypharmacological Compounds Targeting NaV1.5, KV1.5, and K2P Channels for Atrial Fibrillation
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The glycolytic enzyme PKM2 regulates inflammatory osteoclastogenesis by modulating STAT3 phosphorylation
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New routes for spermine biosynthesis
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Resveratrol reduces RVLM neuron activity via activating the AMPK/Sirt3 pathway in stress-induced hypertension
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Structural analyses of apolipoprotein A-IV polymorphisms Q360H and T347S elucidate the inhibitory effect against thrombosis
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