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Serum microbiome-related metabolites—including short-chain fatty acids and indole derivatives—predict outcome and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: a two-timepoint LC–MS study
BackgroundDelayed cerebral ischemia (DCI) remains a major determinant of poor outcome after aneurysmal subarachnoid hemorr...
Anterolateral, lateral, and posterior corridors to complex skull base lesions in sphenocavernous and petroclival regions: microsurgical anatomy with three-dimensional reconstructions and illustrative cases
ObjectiveAccess to complex lesions in the sphenocavernous and petroclival regions are challenging due to their deep locati...
Association between systemic inflammatory markers and otosclerosis: a retrospective case–control study
ObjectiveOtosclerosis is a localized metabolic bone disease of the otic capsule with an inflammatory component. This study...
Antipsychotic effects of aqueous lyophilisate of Ficus mucuso on ketamine-induced schizophrenia
Nutraceuticals and medicinal plants have been studied for the treatment of schizophrenia. Ficus mucuso is a medicinal plan...
Schizophrenia and dementia across the lifespan: epidemiological links, cognitive trajectories, and the pathophysiological interplay
BackgroundSchizophrenia is a severe psychiatric disorder characterized by persistent cognitive impairment across multiple ...
Therapeutic potential of transcutaneous auricular vagus nerve stimulation in cognitive impairment: insights from preclinical and clinical studies
Transcutaneous auricular vagus nerve stimulation (taVNS) is being investigated as a non-invasive neuromodulatory approach ...
Research progress and clinical application of functional magnetic resonance imaging in otolaryngology-head and neck diseases
Functional magnetic resonance imaging (fMRI) is a non-invasive tool that detects neural activity via BOLD signals. In otol...
Multicenter experience of pipeline embolization device used in small caliber vessels (< 2 mm) for intracranial aneurysm treatment and mid-term results
BackgroundFlow diversion stents (FDS), particularly the Pipeline Embolization Device (PED), have been widely used for intr...
Does endolymphatic hydrops affect cochlear and vestibular nerve volumes? An MRI-based morphometric study
ObjectiveTo investigate the relationship between the severity of endolymphatic hydrops (EH) and volumetric changes in coch...
From clinical judgment to biology: a clinician's opinion on the use of blood-based biomarkers in Alzheimer's disease
The diagnosis of Alzheimer's disease (AD) has undergone a substantial transformation over the past two decades. The sh...
Association between systemic immune-inflammation index and all-cause mortality in ischemic stroke patients
ObjectivesThis study is designed to assess the association between the systemic immune-inflammation index (SII) and all-ca...
Early ambulation after surgery in children with cerebral arteriovenous malformations: associated factors and care strategies
BackgroundEarly postoperative ambulation plays a crucial role in accelerating postoperative recovery in pediatric patients...
Neuromodulation approaches and applications in the management of post-stroke pain: a comprehensive review
IntroductionPost-stroke pain (PSP) remains a common and profoundly debilitating consequence of stroke, both in terms of a ...
Impact of early enteral nutrition combined with bedside rehabilitation on functional outcomes and length of stay in patients with severe subarachnoid hemorrhage: a retrospective cohort study
ObjectiveEarly enteral nutrition (EEN) and early rehabilitation have individually demonstrated benefits in neurocritical c...
Mapping the research landscape and evolving hotspots of intensive care unit-acquired weakness: a dual-database bibliometric analysis
PurposeThis review aimed to summarize and map the existing literature to clarify the temporal and spatial distribution, in...
Endovascular treatment of in-stent restenosis after vertebral artery ostial stenting: incidence, risks and outcomes
IntroductionIn-stent restenosis (ISRS) is a major concern following vertebral artery (VA) ostial stenting, potentially lea...
The clinical significance of S100B, APP, and CHI3L1 in autoimmune GFAP astrocytopathy
BackgroundAutoimmune glial fibrillary acidic protein astrocytopathy (A-GFAP-A) is a recently defined immune-mediated disor...
Confirmatory factor analysis and Rasch analysis of the German revised version of the Niigata PPPD questionnaire: NPQ-R
IntroductionPersistent Postural-Perceptual Dizziness (PPPD) is a chronic functional vestibular disorder exacerbated by pos...
Association of physical activity volume with the risks of nervous system diseases: a retrospective cohort study
BackgroundPhysical activity volume (PAV) has been linked to a wide range of health outcomes; however, its association with...
Clinical efficacy and prognostic evaluation of endovascular treatment in acute basilar artery occlusion
ObjectiveTo compare the efficacy and prognosis of endovascular treatment (EVT) versus best medical management (BMM) in acu...
Enriched rehabilitation on brain functional connectivity in patients with post-stroke cognitive impairment
1 Introduction Post-stroke cognitive impairment (PSCI) is one of the most common sequelae of stroke (1). The cognitive c...
Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study
1 Introduction Repetitive head impact (RHI) exposure in sport is a topic of growing concern in clinical medicine, due to...
The clinical impact of recent amphetamine exposure in aneurysmal subarachnoid hemorrhage patients
Introduction Aneurysmal subarachnoid hemorrhage (SAH) accounts for approximately 5% of strokes with an annual incidence ...
Cognition and influencing factors of secondary prevention in patients with ischemic stroke 1 year after discharge in Southwest China: a cross-sectional survey
1 Introduction Stroke is the second leading cause of death worldwide and the leading cause of death in China, where one-...
Involvement of the posterior limb of the internal capsule independently predicts the prognosis of patients with basal ganglia and thalamic hemorrhage
1 Introduction Intracerebral hemorrhage (ICH) is the most lethal and devastating subtype of stroke (1, 2). Survivors have...
Alterations of gray matter volume and functional connectivity in patients with cognitive impairment induced by occupational aluminum exposure: a case-control study
1 Introduction Aluminum (AI) is the third most abundant element in the Earth’s crust and is commonly detected in stable ...
Impact of A1 segment asymmetry on hemodynamic conditions around the circle of Willis and anterior communicating artery aneurysm formation
Background: This study investigates how A1 segment asymmetry, known as A1 dominancy, influences the development of the ant...
Association between hypertension and hearing loss: a systemic review and meta-analysis
Introduction As an escalating concern in the realm of public health, hearing impairment has garnered global focus. As pe...
Retrospective cohort study based on the MIMIC-IV database: analysis of factors influencing all-cause mortality at 30 days, 90 days, 1 year, and 3 years in patients with different types of stroke
1 Introduction Stroke is a severe disease that poses a significant threat to human health. Globally, approximately 17 mi...
Prognostic analysis of endovascular mechanical thrombectomy in stroke patients with acute internal carotid artery obstruction based on circle of Willis variation
Introduction Acute ischemic stroke (AIS) resulting from the occlusion of a large vessel is a critical condition that can...
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