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STAT3 signaling is associated with neuroimmune dysregulation in a Dravet syndrome model and pediatric drug-resistant epilepsy
BackgroundDravet syndrome (DS) is a severe developmental and epileptic encephalopathy, mainly caused by SCN1A gene mutatio...
In silico exploration of electric field distribution in tDCS: integrating white matter anisotropy and subject-specific structural connectivity
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique with promising application in t...
Multimodal machine learning reveals neurobiological signatures of binge-type eating disorders
IntroductionBinge-type eating disorders, including bulimia nervosa (BN) and binge eating disorder (BED), are associated wi...
Decoding acupoint specificity: from neural patterns to bodily maps
The question of whether individual acupoints possess intrinsic functional specificity remains one of the most debated issu...
APOE4 carriers resistant to cognitive decline show unique relationships between cerebrovascular response to exercise and dual-task cognitive-balance performance
BackgroundCognitive-motor dual-tasking is an early marker for cognitive impairment, with particular implications for Apoli...
A multimodal imaging–based integrative framework for HIV-associated cognitive impairment and treatment response
IntroductionCombination antiretroviral therapy (cART) has been shown to reduce inflammation in persons with HIV (PWH), lea...
How yoga shapes the brain: a systematic review
Yoga is a mind–body practice that originated in India thousands of years ago, and which has extended throughout the world ...
Gut microbiota and ALS: cause, consequence or correlation? - a systematic review
BackgroundGut microbiome disturbances have been proposed as contributors to amyotrophic lateral sclerosis (ALS), a multisy...
The vicious cycle of neuroinflammation and ferroptosis in depression: mechanisms and therapeutic targets
Depression is one of the leading causes of disability worldwide, yet its underlying mechanisms remain elusive. Both neuroi...
Mild-cerebellar ataxia due to impaired mitochondrial function caused by the MSTO1 variations
BackgroundMSTO1 encodes a regulator of mitochondrial fusion. Mutations in MSTO1 are linked to a rare mitochondrial disorde...
Retrospective post-hoc subgroup analysis of adjunctive non-invasive vagus nerve stimulation in chronic mTBI with comorbid PTSD
IntroductionPersistent symptoms following mild traumatic brain injury (mTBI) remain a major clinical challenge. Patients w...
Interaction between Poly(ADP-ribose) polymerase-1 and α-synuclein pathology in Parkinson’s disease
Poly(ADP-ribose) polymerase-1 (PARP-1) activation and α-synuclein (α-syn) aggregation are neuropathological hallmarks of P...
Correction: The effect of musical sensory orientation training in improving consciousness level in patients with disorders of consciousness: a pilot study
Disorders of consciousness (DoC) are states of impaired consciousness resulting from serious brain injuries, and includes ...
A novel behavioral paradigm using mice to study predictive postural control
Postural control circuitry performs the essential function of maintaining balance and body position in response to perturb...
A calibration-aware hierarchical CNN-SWIN fusion framework for robust Cross-Dataset brain MRI analysis
IntroductionDeep learning approaches have become central to brain MRI analysis; however, their reliability under dataset s...
Immersive virtual reality as a novel approach to improve social cognition in multiple sclerosis: an EEG-based pilot study
IntroductionMultiple sclerosis (MS) affects different cognitive domains, including social cognition. Immersive Virtual Rea...
Retrospective longitudinal analysis of blood microRNA-7-5p as a possible progression biomarker in people with Parkinson’s disease
BackgroundMicroRNA-7-5p (miR-7-5p) may play a neuroprotective role in people with Parkinson’s disease (PwP), as it has bee...
Toward a dual-pathway model of neuroplastic adaptation in sport: neural efficiency and neural optimization
In recent years, the number of studies investigating the neural efficiency hypothesis (NEH) in athletes has increased subs...
Mitochondrial dysfunction, neuroinflammation, and associated mechanisms in sepsis-associated encephalopathy: from pathogenesis to emerging therapeutics
Sepsis-associated encephalopathy (SAE) is a devastating neurological complication of sepsis, leading to diffuse brain dysf...
Morinda officinalis oligosaccharides alleviate chronic unpredictable mild stress-induced depression through the BDNF/TrkB/CREB pathway and symptoms of sexual dysfunction in mice
1 Introduction Stressful stimuli are aplenty in modern society, and long-term chronic stressful stimuli are an important...
Neural differentiation in perspective: mitochondria as early programmers
Neural differentiation in perspective: mitochondria as early programmers
Introduction Cell differentiation, defined as an assumption of a specialised cellular task, is a hallmark of development...
Sleep patterns and cardiovascular disease risk in US participants: a comprehensive analysis
1 Introduction Cardiovascular disease (CVD), which includes congestive heart failure (CHF), coronary heart disease (CHD)...
Prediction of delirium occurrence using machine learning in acute stroke patients in intensive care unit
1 Introduction Delirium, an acute neuropsychiatric syndrome, is characterized by a sudden loss of attention, change in c...
Corrigendum: Cerebellar white and gray matter abnormalities in temporal lobe epilepsy: a voxel-based morphometry study
In the published article, there was an error in Figure 2 as published. Delete it. Please update the original Figure 3 to F...
Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK and ERK pathways
1 Introduction Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CN...
Meridional anisotropy in contrast sensitivity and visual evoked potential in adults with high myopic astigmatism
1 Introduction Refractive astigmatism is a prevalent refractive error, affecting over 20% (cylindrical errors >0.75 D...
Interplay of epilepsy and long-term potentiation: implications for memory
1 Introduction Long-term potentiation (LTP) stands as a fundamental concept in neuroscience, pivotal for understanding th...
Who is WithMe? EEG features for attention in a visual task, with auditory and rhythmic support
1 Introduction Understanding the human processing of multi-sensory stimuli in relation to attention has been of great int...
Altered static and dynamic spontaneous brain activity in patients with dysthyroid optic neuropathy: a resting-state fMRI study
1 Introduction Dysthyroid optic neuropathy (DON) is one of the most serious complications of thyroid-associated ophthalm...
Noise reduction in brain magnetic resonance imaging using adaptive wavelet thresholding based on linear prediction factor
1 Introduction Medical imaging plays a critical role in modern diagnostics, particularly magnetic resonance imaging (MRI)...
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