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Randomized, double-blind, controlled trial of a combination of alpha-lipoic acid and pregabalin for neuropathic pain: the PAIN-CARE trial
Randomized, double-blind, controlled trial of a combination of alpha-lipoic acid and pregabalin for neuropathic pain: the PAIN-CARE trial
We compared a combination of the nonsedating antioxidant, alpha-lipoic acid (ALA), with the sedating
Placebo analgesia and nocebo hyperalgesia in patients with Alzheimer disease and healthy participants
Placebo analgesia and nocebo hyperalgesia in patients with Alzheimer disease and healthy participants
The role of placebo analgesia and nocebo hyperalgesia in patients with Alzheimer disease (AD) is lar
Alzheimer disease may compromise patients' ability for expectancy-based pain modulation. Now what?
Alzheimer disease may compromise patients' ability for expectancy-based pain modulation. Now what?
The observation that positive treatment expectations can improve treatment outcome by engaging powerful pain modulatory me...
Gut microbiota dysbiosis alters chronic pain behaviors in a humanized transgenic mouse model of sickle cell disease
Gut microbiota dysbiosis alters chronic pain behaviors in a humanized transgenic mouse model of sickle cell disease
Pain is the most common symptom experienced by patients with sickle cell disease (SCD) throughout th
Communication and activation in pain to enhance relationships and treat pain with equity (COOPERATE): a randomized clinical trial
Communication and activation in pain to enhance relationships and treat pain with equity (COOPERATE): a randomized clinical trial
Racialized disparities in chronic pain care are well-documented and persist despite national priorit
Improving the art and science of communication in people living with chronic pain
Improving the art and science of communication in people living with chronic pain
aThe City University of New York School of Medicine, New York, NY, United States bCity College of New York, N...
Overview of the economic burden of musculoskeletal pain in children and adolescents: a systematic review with meta-analysis
Overview of the economic burden of musculoskeletal pain in children and adolescents: a systematic review with meta-analysis
Studies suggest a high economic burden among children and adolescents with musculoskeletal pain. The
Sensing the body matters: profiles of interoceptive sensibility in chronic pain adjustment
Sensing the body matters: profiles of interoceptive sensibility in chronic pain adjustment
Interoception is critical to health regulation and is often disrupted in individuals with chronic pa
How should we measure the relationship between pain and interoception?
How should we measure the relationship between pain and interoception?
aDepartment of Psychology, Queen's University, Kingston, ON, Canada bFaculty of Dentistry, University of Toro...
Association of abdominal aortic calcification and lower back pain in patients with degenerative spondylolisthesis
Association of abdominal aortic calcification and lower back pain in patients with degenerative spondylolisthesis
Abdominal aortic calcification (AAC) is hypothesized to lead to ischemic pain of the lower back. Thi
Neuronal–immune axis alters pain and sensory afferent damage during dental pulp injury
Neuronal–immune axis alters pain and sensory afferent damage during dental pulp injury
Dental pulp tissue is densely innervated by afferent fibers of the trigeminal ganglion. When bacteri
The desire for side-effect information in pain treatment: an experimental analysis of contextual and individual difference factors
The desire for side-effect information in pain treatment: an experimental analysis of contextual and individual difference factors
Informing patients about potential side effects of pain treatment is a requirement that protects pat
Informing about side effects: putting patients (preferences) first
Informing about side effects: putting patients (preferences) first
Informed consent procedures and information about potential side effects of newly prescribed treatments present a classic ...
Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance: Erratum
Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance: Erratum
It was brought to our attention that the Western blot images for nitrated MnSOD in Figure 3A and p-p38 Figure 5B were iden...
Acid-sensing ion channel 3 mediates pain hypersensitivity associated with high-fat diet consumption in mice
Acid-sensing ion channel 3 mediates pain hypersensitivity associated with high-fat diet consumption in mice
Lipid-rich diet is the major cause of obesity, affecting 13% of the worldwide adult population. Obes
Reply to Li et al.
Reply to Li et al.
aDepartment of Nursing and Physiotherapy, Universidad Cardenal Herrera-CEU, CEU Universities, Spain bDepartme...
Correspondence on “The dose-dependent effects of transcutaneous electrical nerve stimulation for pain relief in individuals with fibromyalgia: a systematic review and meta-analysis”
Correspondence on “The dose-dependent effects of transcutaneous electrical nerve stimulation for pain relief in individuals with fibromyalgia: a systematic review and meta-analysis”
aNurse Practitioner, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan bDepartment of Public Health, Chu...
Open-label placebo is an evidence-based treatment option for many chronic conditions
Open-label placebo is an evidence-based treatment option for many chronic conditions
aDivision of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, United States bDepartment of...
Reply to Ballou and Kube
Reply to Ballou and Kube
aSydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia bDepartment of W...
GluCl.CreON enables selective inhibition of molecularly defined pain circuits
GluCl.CreON enables selective inhibition of molecularly defined pain circuits
Insight into nociceptive circuits will ultimately build our understanding of pain processing and aid
Neuropilin-1 is essential for vascular endothelial growth factor A–mediated increase of sensory neuron activity and development of pain-like behaviors
Neuropilin-1 is essential for vascular endothelial growth factor A–mediated increase of sensory neuron activity and development of pain-like behaviors
Neuropilin-1 (NRP-1) is a transmembrane glycoprotein that binds numerous ligands including vascular
Mechanisms of education and graded sensorimotor retraining in people with chronic low back pain: a mediation analysis
Mechanisms of education and graded sensorimotor retraining in people with chronic low back pain: a mediation analysis
An improved understanding of the biopsychosocial influences that contribute to and maintain pain has
The prevalence of persistent post-traumatic headache in adult civilian traumatic brain injury: a systematic review and meta-analysis on the past 14 years
The prevalence of persistent post-traumatic headache in adult civilian traumatic brain injury: a systematic review and meta-analysis on the past 14 years
The most recent prevalence estimate of post-traumatic headache (PTH) after traumatic brain injury (T
Cognitive fatigue weakens the effects of distraction on pain
Cognitive fatigue weakens the effects of distraction on pain
Perceived pain can be viewed because of a competition between nociceptive inputs and other competing
The impact of the social context on the development of secondary hyperalgesia: an experimental study
The impact of the social context on the development of secondary hyperalgesia: an experimental study
Social support has been shown to reduce pain ratings and physiological responses to acute pain stimu
Temporal stability in the prevalence and pattern of co-occurring musculoskeletal pain among people with persistent low back pain: population-based data from the Norwegian HUNT Study, 1995 to 2019
Temporal stability in the prevalence and pattern of co-occurring musculoskeletal pain among people with persistent low back pain: population-based data from the Norwegian HUNT Study, 1995 to 2019
People with persistent low back pain (LBP) often report co-occurring persistent musculoskeletal (MSK
Topical coapplication of hyaluronan with transdermal drug delivery enhancers attenuates inflammatory and neuropathic pain
Topical coapplication of hyaluronan with transdermal drug delivery enhancers attenuates inflammatory and neuropathic pain
We have previously shown that intradermal injection of high-molecular-weight hyaluronan (500-1200 kD
A female-specific role for trigeminal dynorphin in orofacial pain comorbidity
A female-specific role for trigeminal dynorphin in orofacial pain comorbidity
Migraine is commonly reported in patients with temporomandibular disorders (TMDs), but little is kno
“I felt uncertain about my whole future”—a qualitative investigation of people's experiences of navigating uncertainty when seeking care for their low back pain
“I felt uncertain about my whole future”—a qualitative investigation of people's experiences of navigating uncertainty when seeking care for their low back pain
Uncertainty pervades low back pain (LBP). This study aimed to explore individuals' experiences of na
External validation and updating of prognostic prediction models for nonrecovery among older adults seeking primary care for back pain
External validation and updating of prognostic prediction models for nonrecovery among older adults seeking primary care for back pain
Prognostic prediction models for 3 different definitions of nonrecovery were developed in the Back C
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