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A Phenome-Wide Comorbidity Atlas of Age-Related Hearing Loss, Speech-in-Noise Deficits, and Tinnitus: Distinguishing Causal Signals from Correlation
A Phenome-Wide Comorbidity Atlas of Age-Related Hearing Loss, Speech-in-Noise Deficits, and Tinnitus: Distinguishing Causal Signals from Correlation
The present study employed a data-driven and hypothesis-free approach to identify comorbidities associated with age-relate...
Suppression of Low-Frequency Tones in the Organ of Corti Vibrations of the Basal Turn in the Mongolian Gerbil Cochlea
Suppression of Low-Frequency Tones in the Organ of Corti Vibrations of the Basal Turn in the Mongolian Gerbil Cochlea
The basilar membrane (BM) motion evoked by single or two-tone stimuli shows nonlinearity largely confined to the region of...
Longitudinal Vibrations in the Organ of Corti are Limited to Its Core
Longitudinal Vibrations in the Organ of Corti are Limited to Its Core
The goal of this research was to determine where in the organ of Corti (ooC) sound–induced, longitudinal vibrations ...
Clinical Norms for Evaluating Hearing Difficulty in Patients with “Normal” Hearing Thresholds
Clinical Norms for Evaluating Hearing Difficulty in Patients with “Normal” Hearing Thresholds
Ethics Approval and Consent to Participate All methods were approve...
The Effects of Broadband Elicitor Duration on Transient-Evoked Otoacoustic Emissions and a Psychoacoustic Measure of Gain Reduction
The Effects of Broadband Elicitor Duration on Transient-Evoked Otoacoustic Emissions and a Psychoacoustic Measure of Gain Reduction
Measures of the human medial olivocochlear reflex (MOCR) typically rely on long duration (> 100 ms) ...
On the Sharpness of Auditory Filters: Considering Subclinical Deficits Reveals Sharper Otoacoustic Emission Estimates of Frequency Selectivity in Humans
On the Sharpness of Auditory Filters: Considering Subclinical Deficits Reveals Sharper Otoacoustic Emission Estimates of Frequency Selectivity in Humans
Frequency selectivity plays a crucial role in auditory perception, yet its precise characterization in humans remains deba...
Latencies of Pulsed Distortion-Product Otoacoustic Emissions and Their Relation to Auditory Brainstem Responses
Latencies of Pulsed Distortion-Product Otoacoustic Emissions and Their Relation to Auditory Brainstem Responses
To assess system properties of the human auditory system, such as cochlear gain, frequency selectivity, and their dependen...
Enhanced 40 and 80 Hz Auditory Steady State Responses in Patients with Idiopathic Tinnitus
Enhanced 40 and 80 Hz Auditory Steady State Responses in Patients with Idiopathic Tinnitus
This study aimed to investigate changes in auditory processing using auditory steady state responses (ASSR) in patients wi...
Aging in the Primary Auditory Cortex
Aging in the Primary Auditory Cortex
Age-related auditory dysfunction affects half of all individuals 60 years and older, yet its causes are poorly un...
Predicting Cochlear Synaptopathy in Mice with Varying Degrees of Outer Hair Cell Dysfunction Using Auditory Evoked Potentials
Predicting Cochlear Synaptopathy in Mice with Varying Degrees of Outer Hair Cell Dysfunction Using Auditory Evoked Potentials
Although human temporal bones suggest that cochlear synapse numbers decline with age and noise exposure, no validated diag...
Translational Potential of the Avian Cortex
Translational Potential of the Avian Cortex
Birds have contributed to important hearing-science discoveries. Examples include cochlear development, hair cell regenera...
Investigation of Vestibular Dysfunction Requires Renewed Research Enthusiasm
Investigation of Vestibular Dysfunction Requires Renewed Research Enthusiasm
Inner ear research has experienced exponential growth for the last fifty years spurring the creation of novel scientific a...
Anatomical Integrity of the Human Cochlea Estimated with Optical Coherence Tomography for Future Clinical Application
Anatomical Integrity of the Human Cochlea Estimated with Optical Coherence Tomography for Future Clinical Application
The human cochlea is encased within the otic capsule, the densest bone in the body, posing significant challenges for anat...
Regulatory Networks Driving the Specification, Differentiation, and Diversification of Neurons in the Mouse Inner Ear
Regulatory Networks Driving the Specification, Differentiation, and Diversification of Neurons in the Mouse Inner Ear
Vestibular and spiral ganglion neurons (VGNs and SGNs) developed in the inner ear, where they extend fibers to innervate t...
Differentiating Causes of Post-Surgical Conductive Hearing Loss with Optical Coherence Tomography Vibrometry
Differentiating Causes of Post-Surgical Conductive Hearing Loss with Optical Coherence Tomography Vibrometry
To evaluate whether optical coherence tomography (OCT) vibrometry can differentiate causes of conductive hearing loss (CHL...
Effects of Electrode Position on Vestibular Implant Performance in Rhesus Macaque
Effects of Electrode Position on Vestibular Implant Performance in Rhesus Macaque
Vestibular implants that target the three semicircular canal branches of the vestibular nerve can partially restore the 3-...
Correlation of Promontory Vibration and Sound Emission Recorded from the Skin Surface in Bone Conduction Stimulation
Correlation of Promontory Vibration and Sound Emission Recorded from the Skin Surface in Bone Conduction Stimulation
Sound pressure recordings at different positions at the head such as ear canal, nasal cavity, or on the skin are effective...
Effects of Gap Junctions and Inhibition on the Synchronization Behavior of a Biophysically Detailed Neural Network Model of Bushy Cells
Effects of Gap Junctions and Inhibition on the Synchronization Behavior of a Biophysically Detailed Neural Network Model of Bushy Cells
Auditory-nerve fiber (ANF) responses to sound are processed by several distinct neural circuits in the cochlear nucleus (C...
The Suppressibility of Otoacoustic Emissions and Loudness by Low-Frequency Biasing Tones as a Function of Probe Level
The Suppressibility of Otoacoustic Emissions and Loudness by Low-Frequency Biasing Tones as a Function of Probe Level
Biasing of the cochlear partition by tones below 100 Hz is commonly used to investigate cochlear non-linearity. T...
Neuronal Representation of Auditory Distance Percepts vs. Cues in Human Auditory Cortex
Neuronal Representation of Auditory Distance Percepts vs. Cues in Human Auditory Cortex
Perceiving the sound source distance is important in many everyday activities. For sources near the listener, two dominant...
Model-Based Inference of Electrode Distance and Neuronal Density from Measured Detection Thresholds in Cochlear Implant Listeners
Model-Based Inference of Electrode Distance and Neuronal Density from Measured Detection Thresholds in Cochlear Implant Listeners
Cochlear implants (CI) are a highly successful neural prosthesis that can restore hearing in individuals with sensorineura...
Evidence for the Auditory Nerve Generating Envelope Following Responses When Measured from Eardrum Electrodes
Evidence for the Auditory Nerve Generating Envelope Following Responses When Measured from Eardrum Electrodes
Steady-state auditory evoked potentials are useful for studying the human auditory system and diagnosing hearing disorders...
Evaluation of Cochlear Basal Turn Patency in Children with Hearing Loss
Evaluation of Cochlear Basal Turn Patency in Children with Hearing Loss
A patency at the cochlear basal turn (CBTP) can lead to an abrupt leakage of CSF, known as intraoperative CSF gusher. To d...
Crosstalk Signaling Between the Epithelial and Non-Epithelial Compartments of the Mouse Inner Ear
Crosstalk Signaling Between the Epithelial and Non-Epithelial Compartments of the Mouse Inner Ear
The otolith organs of the inner ear consist of the utricle and saccule that detect linear acceleration. These organs rely ...
Developing a Calibration Method to Minimize Variability in Auditory Evoked Potentials
Developing a Calibration Method to Minimize Variability in Auditory Evoked Potentials
To reduce amplitude variability of auditory evoked potentials (AEPs) we developed a circuit that generates an electric cal...
Temporal Pitch Perception of Multi-Channel Stimuli by Cochlear-Implant Users
Temporal Pitch Perception of Multi-Channel Stimuli by Cochlear-Implant Users
To explore the feasibility of cochlear-implant (CI) processing strategies that aim to improve pitch perception by presenti...
Contributions of Auditory Nerve Density and Synchrony to Speech Understanding in Older Cochlear Implant Users
Contributions of Auditory Nerve Density and Synchrony to Speech Understanding in Older Cochlear Implant Users
The majority of adult cochlear implant (CI) recipients are over the age of 65, and previous research in non-implanted olde...
Influence of Myosin Regulatory Light Chain and Myosin Light Chain Kinase on the Physiological Function of Inner Ear Hair Cells
Influence of Myosin Regulatory Light Chain and Myosin Light Chain Kinase on the Physiological Function of Inner Ear Hair Cells
In the receptor organs of the inner ear, hair cells detect mechanical stimuli such as sounds and accelerations by deflecti...
Age-Related Decline in Neural Phase-Locking to Envelope and Temporal Fine Structure Revealed by Frequency Following Responses: A Potential Signature of Cochlear Synaptopathy Impairing Speech Intelligibility
Age-Related Decline in Neural Phase-Locking to Envelope and Temporal Fine Structure Revealed by Frequency Following Responses: A Potential Signature of Cochlear Synaptopathy Impairing Speech Intelligibility
Assessing the contribution of cochlear synaptopathy (CS) to the variability in speech-in-noise intelligibility among indiv...
Cochlear Implantation Outcomes in Genotyped Subjects with Sensorineural Hearing Loss
Cochlear Implantation Outcomes in Genotyped Subjects with Sensorineural Hearing Loss
Cochlear implants (CIs) are an effective rehabilitation option for individuals with severe-to-profound sensorineural heari...
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